Phenotype measure:   Yuan3   HDL_M06

ID, description, units MPD:24471   HDL_M06   HDL cholesterol (plasma HDL)   [mg/dL]  at age 6mo
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 26wks
Procedure lipid profile
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - HDL cholesterol (plasma HDL) at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains27 strains
Mean of the strain means85.8   mg/dL 111   mg/dL
Median of the strain means77.2   mg/dL 108   mg/dL
SD of the strain means± 29.8 ± 36.6
Coefficient of variation (CV)0.348 0.328
Min–max range of strain means48.0   –   167   mg/dL 60.9   –   198   mg/dL
Mean sample size per strain7.6   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 71186.6204 71186.6204 653.4872 < 0.0001
strain 24 379358.723 15806.6135 145.1034 < 0.0001
sex:strain 24 33058.4167 1377.434 12.6447 < 0.0001
Residuals 346 37690.9762 108.9335


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 94.7 8.5   8 3.0 0.0897 81.6, 106.0 0.3
129S1/SvImJ m 128.0 12.4   8 4.39 0.0971 110.0, 146.0 0.46
A/J f 68.2 5.41   7 2.05 0.0794 62.9, 76.3 -0.59
A/J m 70.7 8.12   8 2.87 0.115 60.5, 80.1 -1.11
AKR/J f 75.3 12.6   8 4.46 0.168 52.0, 93.6 -0.35
BALB/cByJ f 72.8 8.33   8 2.94 0.114 59.0, 85.4 -0.44
BALB/cByJ m 119.0 10.9   8 3.84 0.0912 105.0, 134.0 0.21
BTBR T+ Itpr3tf/J f 106.0 5.95   8 2.1 0.0562 98.4, 115.0 0.68
BTBR T+ Itpr3tf/J m 114.0 11.0   8 3.88 0.0961 98.6, 129.0 0.07
BUB/BnJ f 57.2 9.44   8 3.34 0.165 40.9, 74.3 -0.96
BUB/BnJ m 84.5 7.33   8 2.59 0.0868 79.5, 102.0 -0.73
C3H/HeJ f 82.7 2.91   8 1.03 0.0352 78.7, 86.9 -0.1
C3H/HeJ m 108.0 7.87   16 1.97 0.0725 98.0, 127.0 -0.09
C57BL/10J f 71.8 17.5   8 6.18 0.243 54.8, 101.0 -0.47
C57BL/10J m 71.4 4.28   8 1.51 0.0599 64.7, 77.7 -1.09
C57BL/6J f 57.9 3.95   4 1.98 0.0683 52.9, 61.2 -0.93
C57BL/6J m 84.3 9.62   2   6.8 0.114 77.5, 91.1 -0.74
C57BLKS/J f 68.2 19.7   8 6.95 0.288 48.7, 112.0 -0.59
C57BLKS/J m 63.6 7.77   8 2.75 0.122 51.9, 70.4 -1.31
C57BR/cdJ f 77.2 7.55   8 2.67 0.0978 66.1, 90.2 -0.29
C57BR/cdJ m 95.7 13.9   8 4.92 0.145 71.5, 114.0 -0.43
CAST/EiJ f 58.9 12.2   6 4.97 0.207 38.4, 68.4 -0.9
CBA/J m 94.6 9.26   8 3.28 0.0979 79.9, 109.0 -0.46
DBA/2J f 53.8 10.3   8 3.65 0.192 33.0, 63.7 -1.07
DBA/2J m 89.1 3.38   7 1.28 0.0379 85.5, 92.9 -0.61
FVB/NJ f 126.0 13.1   8 4.62 0.104 104.0, 146.0 1.35
FVB/NJ m 170.0 11.8   8 4.16 0.0691 159.0, 194.0 1.6
KK/HlJ f 137.0 11.2   8 3.97 0.0822 120.0, 151.0 1.72
LP/J f 115.0 5.4   5 2.42 0.0471 109.0, 121.0 0.98
LP/J m 112.0 10.7   8 3.77 0.0954 96.1, 124.0 0.02
MOLF/EiJ f 57.0 3.54   7 1.34 0.062 52.0, 62.5 -0.97
MOLF/EiJ m 60.9 6.49   8 2.29 0.107 52.0, 70.3 -1.38
MRL/MpJ m 149.0 9.56   8 3.38 0.0642 134.0, 158.0 1.03
NOD.B10Sn-H2b/J f 91.7 7.4   9 2.47 0.0807 76.9, 100.0 0.2
NOD.B10Sn-H2b/J m 118.0 4.47   7 1.69 0.0377 116.0, 128.0 0.18
NON/ShiLtJ f 104.0 12.4   8 4.38 0.119 79.0, 117.0 0.61
NON/ShiLtJ m 170.0 23.6   8 8.35 0.139 136.0, 198.0 1.6
NZO/HlLtJ f 167.0 9.38   8 3.32 0.056 153.0, 183.0 2.72
NZO/HlLtJ m 198.0 22.6   7 8.53 0.114 156.0, 221.0 2.37
NZW/LacJ f 145.0 10.8   8 3.82 0.0746 130.0, 158.0 1.98
NZW/LacJ m 175.0 9.05   8 3.2 0.0518 165.0, 192.0 1.74
P/J f 106.0 8.03   8 2.84 0.0756 96.6, 119.0 0.68
PL/J f 78.6 10.2   7 3.84 0.129 58.5, 89.7 -0.24
PL/J m 116.0 12.5   13 3.47 0.108 98.1, 147.0 0.13
PWD/PhJ f 86.0 6.77   8 2.39 0.0787 73.3, 94.5 0.01
PWD/PhJ m 108.0 12.3   8 4.36 0.115 84.3, 121.0 -0.09
RIIIS/J f 58.7 5.83   8 2.06 0.0993 50.0, 68.0 -0.91
RIIIS/J m 65.6 11.0   8 3.88 0.167 55.3, 88.6 -1.25
SJL/J f 62.2 8.42   8 2.98 0.135 48.6, 76.3 -0.79
SJL/J m 92.4 9.59   6 3.91 0.104 83.0, 106.0 -0.52
SM/J f 68.5 6.6   16 1.65 0.0964 59.2, 78.7 -0.58
SM/J m 95.3 9.03   8 3.19 0.0948 81.7, 106.0 -0.44
SWR/J f 48.0 5.85   8 2.07 0.122 37.6, 54.1 -1.27
SWR/J m 107.0 8.76   8 3.1 0.0815 98.7, 125.0 -0.12
WSB/EiJ f 92.6 9.21   5 4.12 0.0994 87.7, 109.0 0.23
WSB/EiJ m 146.0 11.6   6 4.73 0.0793 131.0, 159.0 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 94.675 3.6901 101.9328 87.4172
129S1/SvImJ m 127.75 3.6901 135.0078 120.4922
A/J f 68.1571 3.9449 75.9161 60.3982
A/J m 70.725 3.6901 77.9828 63.4672
BALB/cByJ f 72.775 3.6901 80.0328 65.5172
BALB/cByJ m 119.25 3.6901 126.5078 111.9922
BTBR T+ Itpr3tf/J f 105.7625 3.6901 113.0203 98.5047
BTBR T+ Itpr3tf/J m 114.325 3.6901 121.5828 107.0672
BUB/BnJ f 57.1875 3.6901 64.4453 49.9297
BUB/BnJ m 84.45 3.6901 91.7078 77.1922
C3H/HeJ f 82.7 3.6901 89.9578 75.4422
C3H/HeJ m 108.5 2.6093 113.632 103.368
C57BL/10J f 71.8125 3.6901 79.0703 64.5547
C57BL/10J m 71.4125 3.6901 78.6703 64.1547
C57BL/6J f 57.875 5.2186 68.1391 47.6109
C57BL/6J m 84.3 7.3802 98.8156 69.7844
C57BLKS/J f 68.25 3.6901 75.5078 60.9922
C57BLKS/J m 63.6375 3.6901 70.8953 56.3797
C57BR/cdJ f 77.2 3.6901 84.4578 69.9422
C57BR/cdJ m 95.6625 3.6901 102.9203 88.4047
DBA/2J f 53.8375 3.6901 61.0953 46.5797
DBA/2J m 89.1 3.9449 96.8589 81.3411
FVB/NJ f 126.125 3.6901 133.3828 118.8672
FVB/NJ m 170.25 3.6901 177.5078 162.9922
LP/J f 114.8 4.6676 123.9805 105.6195
LP/J m 111.8625 3.6901 119.1203 104.6047
MOLF/EiJ f 57.0 3.9449 64.7589 49.2411
MOLF/EiJ m 60.8625 3.6901 68.1203 53.6047
NOD.B10Sn-H2b/J f 91.7111 3.479 98.5538 84.8684
NOD.B10Sn-H2b/J m 118.4286 3.9449 126.1875 110.6696
NON/ShiLtJ f 104.075 3.6901 111.3328 96.8172
NON/ShiLtJ m 169.5 3.6901 176.7578 162.2422
NZO/HlLtJ f 167.375 3.6901 174.6328 160.1172
NZO/HlLtJ m 198.1429 3.9449 205.9018 190.3839
NZW/LacJ f 144.875 3.6901 152.1328 137.6172
NZW/LacJ m 174.75 3.6901 182.0078 167.4922
PL/J f 78.5571 3.9449 86.3161 70.7982
PL/J m 116.1615 2.8947 121.855 110.468
PWD/PhJ f 86.0 3.6901 93.2578 78.7422
PWD/PhJ m 107.575 3.6901 114.8328 100.3172
RIIIS/J f 58.6875 3.6901 65.9453 51.4297
RIIIS/J m 65.5875 3.6901 72.8453 58.3297
SJL/J f 62.25 3.6901 69.5078 54.9922
SJL/J m 92.3833 4.2609 100.7639 84.0027
SM/J f 68.4625 2.6093 73.5945 63.3305
SM/J m 95.2625 3.6901 102.5203 88.0047
SWR/J f 47.9875 3.6901 55.2453 40.7297
SWR/J m 107.4625 3.6901 114.7203 100.2047
WSB/EiJ f 92.6 4.6676 101.7805 83.4195
WSB/EiJ m 146.0 4.2609 154.3806 137.6194


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 111.2125 2.6093 116.3445 106.0805
A/J both 69.4411 2.7009 74.7532 64.1289
BALB/cByJ both 96.0125 2.6093 101.1445 90.8805
BTBR T+ Itpr3tf/J both 110.0437 2.6093 115.1758 104.9117
BUB/BnJ both 70.8188 2.6093 75.9508 65.6867
C3H/HeJ both 95.6 2.2597 100.0445 91.1555
C57BL/10J both 71.6125 2.6093 76.7445 66.4805
C57BL/6J both 71.0875 4.5194 79.9765 62.1985
C57BLKS/J both 65.9438 2.6093 71.0758 60.8117
C57BR/cdJ both 86.4313 2.6093 91.5633 81.2992
DBA/2J both 71.4687 2.7009 76.7809 66.1566
FVB/NJ both 148.1875 2.6093 153.3195 143.0555
LP/J both 113.3312 2.975 119.1827 107.4798
MOLF/EiJ both 58.9312 2.7009 64.2434 53.6191
NOD.B10Sn-H2b/J both 105.0698 2.6299 110.2425 99.8972
NON/ShiLtJ both 136.7875 2.6093 141.9195 131.6555
NZO/HlLtJ both 182.7589 2.7009 188.0711 177.4468
NZW/LacJ both 159.8125 2.6093 164.9445 154.6805
PL/J both 97.3593 2.4465 102.1712 92.5475
PWD/PhJ both 96.7875 2.6093 101.9195 91.6555
RIIIS/J both 62.1375 2.6093 67.2695 57.0055
SJL/J both 77.3167 2.8183 82.8599 71.7734
SM/J both 81.8625 2.2597 86.307 77.418
SWR/J both 77.725 2.6093 82.857 72.593
WSB/EiJ both 119.3 3.16 125.5152 113.0848




  GWAS USING LINEAR MIXED MODELS