Project measure / variable:   Yuan3   TBIL_M18

ID, description, units MPD:24468   TBIL_M18   bilirubin (serum TBIL)   [µmol/L]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
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  STRAIN COMPARISON PLOT
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Yuan3 - bilirubin (serum TBIL) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains27 strains
Mean of the strain means0.370   µmol/L 0.390   µmol/L
Median of the strain means0.373   µmol/L 0.377   µmol/L
SD of the strain means± 0.0672 ± 0.0672
Coefficient of variation (CV)0.182 0.172
Min–max range of strain means0.208   –   0.510   µmol/L 0.255   –   0.530   µmol/L
Mean sample size per strain7.1   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0326 0.0326 2.7258 0.0998
strain 26 0.8276 0.0318 2.6649 < 0.0001
sex:strain 26 0.5758 0.0221 1.8539 0.0081
Residuals 305 3.6431 0.0119


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.396 0.0568   7 0.0215 0.144 0.32, 0.49 0.39
129S1/SvImJ m 0.394 0.16   7 0.0605 0.406 0.05, 0.53 0.06
A/J f 0.408 0.0688   8 0.0243 0.169 0.31, 0.53 0.57
A/J m 0.488 0.128   6 0.0521 0.261 0.36, 0.69 1.46
BALB/cByJ f 0.457 0.129   7 0.0487 0.282 0.36, 0.65 1.3
BALB/cByJ m 0.38 0.0458   5 0.0205 0.121 0.33, 0.42 -0.14
BTBR T+ Itpr3tf/J f 0.487 0.165   6 0.0674 0.339 0.31, 0.74 1.75
BTBR T+ Itpr3tf/J m 0.354 0.0688   5 0.0308 0.194 0.25, 0.43 -0.53
BUB/BnJ f 0.372 0.0409   5 0.0183 0.11 0.32, 0.43 0.04
C3H/HeJ f 0.313 0.0859   6 0.0351 0.274 0.15, 0.4 -0.84
C3H/HeJ m 0.296 0.136   8 0.0481 0.459 0.1, 0.5 -1.39
C57BL/10J f 0.393 0.0725   7 0.0274 0.185 0.28, 0.5 0.35
C57BL/10J m 0.48 0.18   7 0.0679 0.374 0.19, 0.72 1.34
C57BL/6J f 0.326 0.0875   8 0.0309 0.268 0.16, 0.46 -0.65
C57BL/6J m 0.473 0.154   7 0.0581 0.325 0.26, 0.74 1.24
C57BLKS/J f 0.373 0.0753   6 0.0307 0.202 0.25, 0.44 0.05
C57BLKS/J m 0.379 0.0727   7 0.0275 0.192 0.27, 0.48 -0.16
C57BR/cdJ f 0.323 0.128   8 0.0454 0.398 0.22, 0.58 -0.69
C57BR/cdJ m 0.345 0.0862   8 0.0305 0.25 0.21, 0.48 -0.66
C57L/J f 0.409 0.097   8 0.0343 0.237 0.23, 0.55 0.59
C57L/J m 0.447 0.0723   6 0.0295 0.162 0.32, 0.53 0.85
CBA/J f 0.413 0.0696   8 0.0246 0.169 0.31, 0.53 0.65
CBA/J m 0.377 0.116   6 0.0474 0.308 0.24, 0.57 -0.19
DBA/2J f 0.388 0.216   5 0.0965 0.556 0.01, 0.55 0.28
DBA/2J m 0.46 0.122   8 0.0432 0.266 0.33, 0.66 1.05
FVB/NJ f 0.434 0.0725   8 0.0256 0.167 0.35, 0.53 0.96
FVB/NJ m 0.367 0.0902   3 0.0521 0.246 0.28, 0.46 -0.34
KK/HlJ f 0.346 0.123   10 0.039 0.356 0.1, 0.55 -0.35
KK/HlJ m 0.473 0.0925   7 0.035 0.196 0.33, 0.57 1.24
LP/J f 0.329 0.152   7 0.0574 0.462 0.14, 0.55 -0.6
LP/J m 0.311 0.165   8 0.0585 0.532 0.05, 0.57 -1.17
MRL/MpJ f 0.27 0.113   2   0.08 0.419 0.19, 0.35 -1.48
MRL/MpJ m 0.53 0.101   5 0.0451 0.19 0.4, 0.63 2.09
NOD.B10Sn-H2b/J f 0.307 0.0862   7 0.0326 0.281 0.22, 0.44 -0.93
NOD.B10Sn-H2b/J m 0.35 0.0469   4 0.0235 0.134 0.3, 0.39 -0.59
NON/ShiLtJ f 0.356 0.102   14 0.0274 0.288 0.2, 0.52 -0.2
NON/ShiLtJ m 0.419 0.0782   7 0.0296 0.187 0.29, 0.52 0.44
NZO/HlLtJ f 0.278 0.122   9 0.0408 0.44 0.13, 0.46 -1.36
NZW/LacJ f 0.336 0.0688   5 0.0308 0.205 0.27, 0.44 -0.5
NZW/LacJ m 0.337 0.134   7 0.0507 0.398 0.05, 0.45 -0.78
P/J f 0.51 0.0962   5 0.043 0.189 0.4, 0.66 2.09
P/J m 0.255 0.132   4 0.0659 0.517 0.12, 0.43 -2.0
PL/J f 0.208 0.118   6 0.0483 0.567 0.06, 0.37 -2.4
PL/J m 0.302 0.0236   4 0.0118 0.0781 0.27, 0.32 -1.3
PWD/PhJ f 0.399 0.106   7 0.0401 0.266 0.24, 0.53 0.44
PWD/PhJ m 0.42 0.0552   5 0.0247 0.131 0.34, 0.48 0.45
RIIIS/J f 0.467 0.135   7 0.0512 0.29 0.31, 0.66 1.45
RIIIS/J m 0.444 0.0852   8 0.0301 0.192 0.36, 0.59 0.81
SJL/J f 0.336 0.109   8 0.0386 0.325 0.23, 0.57 -0.5
SJL/J m 0.36 0.0756   6 0.0309 0.21 0.27, 0.47 -0.44
SM/J f 0.391 0.131   7 0.0496 0.336 0.29, 0.66 0.32
SM/J m 0.348 0.0217   5 0.0097 0.0623 0.32, 0.37 -0.62
SWR/J f 0.38 0.0715   8 0.0253 0.188 0.27, 0.49 0.16
SWR/J m 0.368 0.134   6 0.0549 0.365 0.14, 0.54 -0.32
WSB/EiJ f 0.311 0.0753   8 0.0266 0.242 0.21, 0.43 -0.87
WSB/EiJ m 0.364 0.0744   7 0.0281 0.204 0.28, 0.5 -0.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3957 0.0413 0.477 0.3144
129S1/SvImJ m 0.3943 0.0413 0.4756 0.313
A/J f 0.4075 0.0386 0.4835 0.3315
A/J m 0.4883 0.0446 0.5761 0.4005
BALB/cByJ f 0.4571 0.0413 0.5384 0.3759
BALB/cByJ m 0.38 0.0489 0.4762 0.2838
BTBR T+ Itpr3tf/J f 0.4867 0.0446 0.5745 0.3989
BTBR T+ Itpr3tf/J m 0.354 0.0489 0.4502 0.2578
C3H/HeJ f 0.3133 0.0446 0.4011 0.2255
C3H/HeJ m 0.2962 0.0386 0.3723 0.2202
C57BL/10J f 0.3929 0.0413 0.4741 0.3116
C57BL/10J m 0.48 0.0413 0.5613 0.3987
C57BL/6J f 0.3263 0.0386 0.4023 0.2502
C57BL/6J m 0.4729 0.0413 0.5541 0.3916
C57BLKS/J f 0.3733 0.0446 0.4611 0.2855
C57BLKS/J m 0.3786 0.0413 0.4599 0.2973
C57BR/cdJ f 0.3225 0.0386 0.3985 0.2465
C57BR/cdJ m 0.345 0.0386 0.421 0.269
C57L/J f 0.4088 0.0386 0.4848 0.3327
C57L/J m 0.4467 0.0446 0.5345 0.3589
CBA/J f 0.4125 0.0386 0.4885 0.3365
CBA/J m 0.3767 0.0446 0.4645 0.2889
DBA/2J f 0.388 0.0489 0.4842 0.2918
DBA/2J m 0.46 0.0386 0.536 0.384
FVB/NJ f 0.4338 0.0386 0.5098 0.3577
FVB/NJ m 0.3667 0.0631 0.4908 0.2425
KK/HlJ f 0.346 0.0346 0.414 0.278
KK/HlJ m 0.4729 0.0413 0.5541 0.3916
LP/J f 0.3286 0.0413 0.4099 0.2473
LP/J m 0.3112 0.0386 0.3873 0.2352
MRL/MpJ f 0.27 0.0773 0.4221 0.1179
MRL/MpJ m 0.53 0.0489 0.6262 0.4338
NOD.B10Sn-H2b/J f 0.3071 0.0413 0.3884 0.2259
NOD.B10Sn-H2b/J m 0.35 0.0546 0.4575 0.2425
NON/ShiLtJ f 0.3564 0.0292 0.4139 0.299
NON/ShiLtJ m 0.4186 0.0413 0.4999 0.3373
NZW/LacJ f 0.336 0.0489 0.4322 0.2398
NZW/LacJ m 0.3371 0.0413 0.4184 0.2559
P/J f 0.51 0.0489 0.6062 0.4138
P/J m 0.255 0.0546 0.3625 0.1475
PL/J f 0.2083 0.0446 0.2961 0.1205
PL/J m 0.3025 0.0546 0.41 0.195
PWD/PhJ f 0.3986 0.0413 0.4799 0.3173
PWD/PhJ m 0.42 0.0489 0.5162 0.3238
RIIIS/J f 0.4671 0.0413 0.5484 0.3859
RIIIS/J m 0.4438 0.0386 0.5198 0.3677
SJL/J f 0.3362 0.0386 0.4123 0.2602
SJL/J m 0.36 0.0446 0.4478 0.2722
SM/J f 0.3914 0.0413 0.4727 0.3101
SM/J m 0.348 0.0489 0.4442 0.2518
SWR/J f 0.38 0.0386 0.456 0.304
SWR/J m 0.3683 0.0446 0.4561 0.2805
WSB/EiJ f 0.3113 0.0386 0.3873 0.2352
WSB/EiJ m 0.3643 0.0413 0.4456 0.283


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.395 0.0292 0.4525 0.3375
A/J both 0.4479 0.0295 0.506 0.3898
BALB/cByJ both 0.4186 0.032 0.4815 0.3556
BTBR T+ Itpr3tf/J both 0.4203 0.0331 0.4854 0.3552
C3H/HeJ both 0.3048 0.0295 0.3629 0.2467
C57BL/10J both 0.4364 0.0292 0.4939 0.379
C57BL/6J both 0.3996 0.0283 0.4552 0.3439
C57BLKS/J both 0.376 0.0304 0.4358 0.3161
C57BR/cdJ both 0.3338 0.0273 0.3875 0.28
C57L/J both 0.4277 0.0295 0.4858 0.3696
CBA/J both 0.3946 0.0295 0.4527 0.3365
DBA/2J both 0.424 0.0312 0.4853 0.3627
FVB/NJ both 0.4002 0.037 0.473 0.3274
KK/HlJ both 0.4094 0.0269 0.4624 0.3564
LP/J both 0.3199 0.0283 0.3756 0.2643
MRL/MpJ both 0.4 0.0457 0.49 0.31
NOD.B10Sn-H2b/J both 0.3286 0.0343 0.396 0.2612
NON/ShiLtJ both 0.3875 0.0253 0.4373 0.3377
NZW/LacJ both 0.3366 0.032 0.3995 0.2736
P/J both 0.3825 0.0367 0.4546 0.3104
PL/J both 0.2554 0.0353 0.3248 0.186
PWD/PhJ both 0.4093 0.032 0.4722 0.3463
RIIIS/J both 0.4554 0.0283 0.5111 0.3998
SJL/J both 0.3481 0.0295 0.4062 0.2901
SM/J both 0.3697 0.032 0.4327 0.3068
SWR/J both 0.3742 0.0295 0.4322 0.3161
WSB/EiJ both 0.3378 0.0283 0.3934 0.2821




  GWAS USING LINEAR MIXED MODELS