Project measure / variable:   Yuan3   TBIL_M12

ID, description, units MPD:24467   TBIL_M12   bilirubin (serum TBIL)   [µmol/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
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  STRAIN COMPARISON PLOT
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Yuan3 - bilirubin (serum TBIL) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means0.404   µmol/L 0.436   µmol/L
Median of the strain means0.396   µmol/L 0.419   µmol/L
SD of the strain means± 0.0974 ± 0.0682
Coefficient of variation (CV)0.241 0.156
Min–max range of strain means0.221   –   0.603   µmol/L 0.337   –   0.588   µmol/L
Mean sample size per strain7.1   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0887 0.0887 8.9104 0.003
strain 28 1.3316 0.0476 4.7767 < 0.0001
sex:strain 28 1.0888 0.0389 3.9059 < 0.0001
Residuals 345 3.4348 0.01


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.376 0.0578   8 0.0204 0.154 0.29, 0.45 -0.28
129S1/SvImJ m 0.419 0.107   8 0.0379 0.256 0.28, 0.56 -0.25
A/J f 0.288 0.0968   6 0.0395 0.336 0.15, 0.39 -1.19
A/J m 0.511 0.0687   15 0.0177 0.135 0.38, 0.6 1.1
AKR/J f 0.575 0.0919   2   0.065 0.16 0.51, 0.64 1.76
AKR/J m 0.337 0.168   3 0.0968 0.498 0.23, 0.53 -1.45
BALB/cByJ f 0.289 0.0795   7 0.03 0.275 0.17, 0.41 -1.18
BALB/cByJ m 0.426 0.141   8 0.0497 0.33 0.29, 0.7 -0.15
BTBR T+ Itpr3tf/J f 0.449 0.0975   8 0.0345 0.217 0.33, 0.64 0.47
BTBR T+ Itpr3tf/J m 0.463 0.073   7 0.0276 0.158 0.39, 0.59 0.39
BUB/BnJ f 0.522 0.178   6 0.0726 0.341 0.38, 0.86 1.22
BUB/BnJ m 0.426 0.0803   9 0.0268 0.189 0.35, 0.62 -0.15
C3H/HeJ f 0.341 0.108   8 0.0383 0.317 0.16, 0.47 -0.64
C3H/HeJ m 0.469 0.136   7 0.0514 0.29 0.37, 0.77 0.48
C57BL/10J f 0.396 0.104   8 0.0367 0.262 0.2, 0.53 -0.08
C57BL/10J m 0.403 0.166   7 0.0629 0.413 0.14, 0.59 -0.48
C57BL/6J f 0.474 0.141   8 0.0499 0.298 0.3, 0.64 0.72
C57BL/6J m 0.577 0.085   6 0.0347 0.147 0.42, 0.65 2.07
C57BLKS/J f 0.603 0.126   8 0.0444 0.208 0.46, 0.8 2.05
C57BLKS/J m 0.409 0.0429   8 0.0152 0.105 0.35, 0.48 -0.4
C57BR/cdJ f 0.349 0.0895   8 0.0316 0.257 0.18, 0.49 -0.56
C57BR/cdJ m 0.476 0.0602   8 0.0213 0.126 0.4, 0.57 0.59
C57L/J f 0.278 0.168   6 0.0687 0.605 0.03, 0.46 -1.29
C57L/J m 0.408 0.0886   8 0.0313 0.217 0.3, 0.54 -0.41
CAST/EiJ f 0.221 0.157   8 0.0555 0.71 0.01, 0.41 -1.88
CBA/J f 0.37 0.114   7 0.0429 0.307 0.17, 0.53 -0.35
CBA/J m 0.4 0.116   6 0.0475 0.291 0.2, 0.5 -0.53
DBA/2J f 0.483 0.081   4 0.0405 0.168 0.39, 0.56 0.81
DBA/2J m 0.37 0.0869   6 0.0355 0.235 0.27, 0.52 -0.97
FVB/NJ f 0.491 0.0449   8 0.0159 0.0913 0.43, 0.56 0.9
FVB/NJ m 0.451 0.072   7 0.0272 0.159 0.35, 0.55 0.22
KK/HlJ f 0.591 0.124   8 0.0438 0.209 0.38, 0.82 1.92
KK/HlJ m 0.588 0.161   6 0.0657 0.274 0.34, 0.73 2.23
LP/J f 0.311 0.145   7 0.0548 0.465 0.1, 0.44 -0.95
LP/J m 0.384 0.125   7 0.0472 0.325 0.19, 0.53 -0.76
MRL/MpJ f 0.325 0.0481   8 0.017 0.148 0.27, 0.4 -0.81
MRL/MpJ m 0.535 0.102   8 0.0361 0.191 0.42, 0.74 1.45
NOD.B10Sn-H2b/J f 0.342 0.0223   6 0.0091 0.0652 0.31, 0.37 -0.63
NOD.B10Sn-H2b/J m 0.387 0.0774   7 0.0293 0.2 0.27, 0.49 -0.72
NON/ShiLtJ f 0.485 0.0687   8 0.0243 0.142 0.36, 0.56 0.84
NON/ShiLtJ m 0.403 0.0824   7 0.0311 0.205 0.29, 0.49 -0.48
NZO/HlLtJ f 0.504 0.0553   7 0.0209 0.11 0.41, 0.57 1.03
NZO/HlLtJ m 0.385 0.0885   6 0.0361 0.23 0.29, 0.5 -0.75
NZW/LacJ f 0.329 0.11   8 0.0387 0.333 0.16, 0.51 -0.77
NZW/LacJ m 0.42 0.0676   8 0.0239 0.161 0.29, 0.49 -0.24
P/J f 0.404 0.0723   8 0.0256 0.179 0.31, 0.49 0.0
PL/J f 0.44 0.0608   3 0.0351 0.138 0.4, 0.51 0.37
PL/J m 0.532 0.1   5 0.0448 0.188 0.42, 0.63 1.41
PWD/PhJ f 0.368 0.0821   8 0.029 0.223 0.25, 0.51 -0.37
PWD/PhJ m 0.37 0.103   7 0.0389 0.278 0.23, 0.52 -0.97
RIIIS/J f 0.396 0.101   8 0.0357 0.255 0.29, 0.57 -0.08
RIIIS/J m 0.426 0.0912   8 0.0322 0.214 0.24, 0.53 -0.15
SJL/J f 0.312 0.121   6 0.0492 0.387 0.13, 0.44 -0.94
SJL/J m 0.368 0.0263   4 0.0131 0.0716 0.33, 0.39 -1.0
SM/J f 0.461 0.0882   7 0.0333 0.191 0.32, 0.61 0.59
SM/J m 0.389 0.0801   9 0.0267 0.206 0.28, 0.51 -0.69
SWR/J f 0.33 0.062   6 0.0253 0.188 0.26, 0.41 -0.76
SWR/J m 0.359 0.0853   7 0.0323 0.238 0.22, 0.45 -1.13
WSB/EiJ f 0.411 0.074   7 0.028 0.18 0.34, 0.52 0.08
WSB/EiJ m 0.555 0.148   2   0.105 0.268 0.45, 0.66 1.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.3762 0.0353 0.4456 0.3069
129S1/SvImJ m 0.4187 0.0353 0.4881 0.3494
A/J f 0.2883 0.0407 0.3685 0.2082
A/J m 0.5107 0.0258 0.5613 0.46
AKR/J f 0.575 0.0706 0.7138 0.4362
AKR/J m 0.3367 0.0576 0.45 0.2234
BALB/cByJ f 0.2886 0.0377 0.3627 0.2144
BALB/cByJ m 0.4263 0.0353 0.4956 0.3569
BTBR T+ Itpr3tf/J f 0.4487 0.0353 0.5181 0.3794
BTBR T+ Itpr3tf/J m 0.4629 0.0377 0.537 0.3887
BUB/BnJ f 0.5217 0.0407 0.6018 0.4415
BUB/BnJ m 0.4256 0.0333 0.491 0.3601
C3H/HeJ f 0.3412 0.0353 0.4106 0.2719
C3H/HeJ m 0.4686 0.0377 0.5427 0.3944
C57BL/10J f 0.3962 0.0353 0.4656 0.3269
C57BL/10J m 0.4029 0.0377 0.477 0.3287
C57BL/6J f 0.4737 0.0353 0.5431 0.4044
C57BL/6J m 0.5767 0.0407 0.6568 0.4965
C57BLKS/J f 0.6025 0.0353 0.6719 0.5331
C57BLKS/J m 0.4088 0.0353 0.4781 0.3394
C57BR/cdJ f 0.3487 0.0353 0.4181 0.2794
C57BR/cdJ m 0.4762 0.0353 0.5456 0.4069
C57L/J f 0.2783 0.0407 0.3585 0.1982
C57L/J m 0.4075 0.0353 0.4769 0.3381
CBA/J f 0.37 0.0377 0.4442 0.2958
CBA/J m 0.4 0.0407 0.4801 0.3199
DBA/2J f 0.4825 0.0499 0.5806 0.3844
DBA/2J m 0.37 0.0407 0.4501 0.2899
FVB/NJ f 0.4912 0.0353 0.5606 0.4219
FVB/NJ m 0.4514 0.0377 0.5256 0.3773
KK/HlJ f 0.5912 0.0353 0.6606 0.5219
KK/HlJ m 0.5883 0.0407 0.6685 0.5082
LP/J f 0.3114 0.0377 0.3856 0.2373
LP/J m 0.3843 0.0377 0.4585 0.3101
MRL/MpJ f 0.325 0.0353 0.3944 0.2556
MRL/MpJ m 0.535 0.0353 0.6044 0.4656
NOD.B10Sn-H2b/J f 0.3417 0.0407 0.4218 0.2615
NOD.B10Sn-H2b/J m 0.3871 0.0377 0.4613 0.313
NON/ShiLtJ f 0.485 0.0353 0.5544 0.4156
NON/ShiLtJ m 0.4029 0.0377 0.477 0.3287
NZO/HlLtJ f 0.5043 0.0377 0.5785 0.4301
NZO/HlLtJ m 0.385 0.0407 0.4651 0.3049
NZW/LacJ f 0.3287 0.0353 0.3981 0.2594
NZW/LacJ m 0.42 0.0353 0.4894 0.3506
PL/J f 0.44 0.0576 0.5533 0.3267
PL/J m 0.532 0.0446 0.6198 0.4442
PWD/PhJ f 0.3675 0.0353 0.4369 0.2981
PWD/PhJ m 0.37 0.0377 0.4442 0.2958
RIIIS/J f 0.3962 0.0353 0.4656 0.3269
RIIIS/J m 0.4262 0.0353 0.4956 0.3569
SJL/J f 0.3117 0.0407 0.3918 0.2315
SJL/J m 0.3675 0.0499 0.4656 0.2694
SM/J f 0.4614 0.0377 0.5356 0.3873
SM/J m 0.3889 0.0333 0.4543 0.3235
SWR/J f 0.33 0.0407 0.4101 0.2499
SWR/J m 0.3586 0.0377 0.4327 0.2844
WSB/EiJ f 0.4114 0.0377 0.4856 0.3373
WSB/EiJ m 0.555 0.0706 0.6938 0.4162


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3975 0.0249 0.4466 0.3484
A/J both 0.3995 0.0241 0.4469 0.3521
AKR/J both 0.4558 0.0455 0.5454 0.3663
BALB/cByJ both 0.3574 0.0258 0.4082 0.3066
BTBR T+ Itpr3tf/J both 0.4558 0.0258 0.5066 0.405
BUB/BnJ both 0.4736 0.0263 0.5253 0.4219
C3H/HeJ both 0.4049 0.0258 0.4557 0.3541
C57BL/10J both 0.3996 0.0258 0.4503 0.3488
C57BL/6J both 0.5252 0.0269 0.5782 0.4722
C57BLKS/J both 0.5056 0.0249 0.5547 0.4566
C57BR/cdJ both 0.4125 0.0249 0.4616 0.3634
C57L/J both 0.3429 0.0269 0.3959 0.2899
CBA/J both 0.385 0.0278 0.4396 0.3304
DBA/2J both 0.4262 0.0322 0.4896 0.3629
FVB/NJ both 0.4713 0.0258 0.5221 0.4206
KK/HlJ both 0.5898 0.0269 0.6428 0.5368
LP/J both 0.3479 0.0267 0.4003 0.2954
MRL/MpJ both 0.43 0.0249 0.4791 0.3809
NOD.B10Sn-H2b/J both 0.3644 0.0278 0.419 0.3098
NON/ShiLtJ both 0.4439 0.0258 0.4947 0.3931
NZO/HlLtJ both 0.4446 0.0278 0.4992 0.3901
NZW/LacJ both 0.3744 0.0249 0.4234 0.3253
PL/J both 0.486 0.0364 0.5577 0.4143
PWD/PhJ both 0.3687 0.0258 0.4195 0.318
RIIIS/J both 0.4112 0.0249 0.4603 0.3622
SJL/J both 0.3396 0.0322 0.4029 0.2762
SM/J both 0.4252 0.0251 0.4746 0.3757
SWR/J both 0.3443 0.0278 0.3989 0.2897
WSB/EiJ both 0.4832 0.04 0.5619 0.4045




  GWAS USING LINEAR MIXED MODELS