Project measure / variable:   Yuan3   CO2_M18

ID, description, units MPD:24463   CO2_M18   dissolved-ionized carbon dioxide (CO2)   [mmol/L]  at age 18mo  
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - dissolved-ionized carbon dioxide (CO2) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means20.0   mmol/L 19.9   mmol/L
Median of the strain means19.8   mmol/L 19.9   mmol/L
SD of the strain means± 2.22 ± 2.05
Coefficient of variation (CV)0.111 0.103
Min–max range of strain means15.9   –   25.4   mmol/L 16.2   –   24.8   mmol/L
Mean sample size per strain7.1   mice 6.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.1079 0.1079 0.0173 0.8955
strain 26 1093.4147 42.0544 6.7383 < 0.0001
sex:strain 26 380.8676 14.6488 2.3471 0.0003
Residuals 313 1953.4684 6.2411


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.3 2.93   7 1.11 0.144 16.1, 23.9 0.15
129S1/SvImJ m 20.6 4.91   8 1.73 0.238 12.1, 24.9 0.33
A/J f 21.0 2.13   8 0.753 0.102 18.5, 23.7 0.47
A/J m 17.8 3.06   6 1.25 0.171 12.9, 22.1 -1.04
BALB/cByJ f 20.5 1.89   7 0.716 0.0924 18.1, 23.7 0.24
BALB/cByJ m 20.9 3.03   6 1.24 0.145 17.7, 25.1 0.48
BTBR T+ Itpr3tf/J f 20.7 0.845   6 0.345 0.0408 19.6, 21.6 0.33
BTBR T+ Itpr3tf/J m 22.2 1.7   5 0.76 0.0767 20.2, 23.4 1.12
BUB/BnJ f 21.5 2.66   5 1.19 0.124 19.4, 26.0 0.69
C3H/HeJ f 22.8 1.73   6 0.708 0.0761 19.8, 24.2 1.27
C3H/HeJ m 21.1 3.92   8 1.39 0.186 14.8, 26.0 0.58
C57BL/10J f 19.5 1.41   7 0.534 0.0723 17.4, 21.8 -0.21
C57BL/10J m 18.3 2.11   7 0.799 0.115 14.1, 20.1 -0.79
C57BL/6J f 17.8 1.17   8 0.413 0.0655 16.4, 20.0 -0.97
C57BL/6J m 17.5 2.93   7 1.11 0.167 13.2, 21.4 -1.18
C57BLKS/J f 16.7 2.89   7 1.09 0.173 12.2, 20.8 -1.47
C57BLKS/J m 21.9 2.78   8 0.983 0.127 17.8, 25.8 0.97
C57BR/cdJ f 17.8 2.17   8 0.768 0.122 14.4, 20.4 -0.97
C57BR/cdJ m 16.7 2.4   8 0.85 0.144 11.6, 19.2 -1.57
C57L/J f 22.3 0.68   8 0.24 0.0305 21.5, 23.3 1.05
C57L/J m 21.9 1.2   6 0.492 0.055 20.6, 23.6 0.97
CBA/J f 20.2 1.87   8 0.66 0.0924 16.4, 22.0 0.11
CBA/J m 18.9 1.52   6 0.619 0.0804 17.4, 21.2 -0.5
DBA/2J f 19.8 3.08   5 1.38 0.156 16.2, 24.0 -0.07
DBA/2J m 18.9 2.19   7 0.827 0.116 16.4, 21.8 -0.5
FVB/NJ f 19.2 1.96   7 0.741 0.102 16.6, 21.6 -0.34
FVB/NJ m 19.3 0.837   5 0.374 0.0434 18.5, 20.7 -0.3
KK/HlJ f 19.3 4.63   10 1.47 0.24 13.0, 25.5 -0.3
KK/HlJ m 18.5 3.25   7 1.23 0.176 14.6, 22.4 -0.69
LP/J f 21.1 1.57   7 0.594 0.0746 18.5, 22.8 0.51
LP/J m 20.4 2.71   8 0.959 0.133 16.6, 23.8 0.24
MRL/MpJ f 25.4 4.53   2   3.2 0.178 22.2, 28.6 2.44
MRL/MpJ m 24.8 1.26   5 0.566 0.051 23.0, 26.2 2.39
NOD.B10Sn-H2b/J f 21.8 5.23   7 1.98 0.241 13.9, 30.5 0.83
NOD.B10Sn-H2b/J m 20.4 3.12   4 1.56 0.153 16.5, 23.7 0.24
NON/ShiLtJ f 18.4 2.07   14 0.553 0.112 14.8, 23.0 -0.7
NON/ShiLtJ m 16.2 1.74   7 0.657 0.107 12.7, 18.1 -1.82
NZO/HlLtJ f 17.7 4.22   9 1.41 0.238 10.5, 22.5 -1.02
NZO/HlLtJ m 21.3 0.0   1   0.0 0.0 21.3, 21.3 0.68
NZW/LacJ f 23.6 1.51   5 0.677 0.0641 21.1, 24.7 1.63
NZW/LacJ m 21.9 1.21   7 0.457 0.0552 20.2, 23.4 0.97
P/J f 19.0 1.74   5 0.776 0.0914 16.9, 21.7 -0.43
P/J m 21.6 2.29   4 1.14 0.106 19.3, 24.7 0.82
PL/J f 19.3 1.35   6 0.551 0.0699 17.0, 21.0 -0.3
PL/J m 18.9 2.07   4 1.03 0.11 16.3, 21.3 -0.5
PWD/PhJ f 20.5 0.863   7 0.326 0.0421 19.6, 22.0 0.24
PWD/PhJ m 21.1 1.84   8 0.649 0.0869 18.2, 24.2 0.58
RIIIS/J f 18.9 3.99   8 1.41 0.21 13.8, 27.4 -0.48
RIIIS/J m 18.8 1.73   8 0.611 0.0918 15.8, 21.4 -0.55
SJL/J f 23.2 1.8   8 0.636 0.0775 20.6, 26.5 1.45
SJL/J m 18.8 2.36   6 0.965 0.126 16.1, 22.1 -0.55
SM/J f 18.2 2.56   7 0.968 0.141 14.2, 21.2 -0.79
SM/J m 23.0 1.81   5 0.811 0.079 19.8, 24.4 1.51
SWR/J f 16.6 2.18   8 0.769 0.131 12.9, 19.6 -1.51
SWR/J m 18.6 2.15   6 0.879 0.116 15.6, 20.2 -0.64
WSB/EiJ f 15.9 1.87   8 0.662 0.118 13.2, 18.0 -1.83
WSB/EiJ m 17.4 0.82   7 0.31 0.047 16.4, 18.4 -1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.3286 0.9442 22.1864 18.4707
129S1/SvImJ m 20.6 0.8833 22.3379 18.8621
A/J f 20.975 0.8833 22.7129 19.2371
A/J m 17.8333 1.0199 19.84 15.8266
BALB/cByJ f 20.5 0.9442 22.3579 18.6421
BALB/cByJ m 20.9 1.0199 22.9067 18.8933
BTBR T+ Itpr3tf/J f 20.7333 1.0199 22.74 18.7266
BTBR T+ Itpr3tf/J m 22.16 1.1172 24.3582 19.9618
C3H/HeJ f 22.8 1.0199 24.8067 20.7933
C3H/HeJ m 21.05 0.8833 22.7879 19.3121
C57BL/10J f 19.5429 0.9442 21.4007 17.685
C57BL/10J m 18.3286 0.9442 20.1864 16.4707
C57BL/6J f 17.825 0.8833 19.5629 16.0871
C57BL/6J m 17.5429 0.9442 19.4007 15.685
C57BLKS/J f 16.7429 0.9442 18.6007 14.885
C57BLKS/J m 21.9 0.8833 23.6379 20.1621
C57BR/cdJ f 17.8 0.8833 19.5379 16.0621
C57BR/cdJ m 16.725 0.8833 18.4629 14.9871
C57L/J f 22.325 0.8833 24.0629 20.5871
C57L/J m 21.9 1.0199 23.9067 19.8933
CBA/J f 20.2 0.8833 21.9379 18.4621
CBA/J m 18.8667 1.0199 20.8734 16.86
DBA/2J f 19.76 1.1172 21.9582 17.5618
DBA/2J m 18.8857 0.9442 20.7436 17.0279
FVB/NJ f 19.2286 0.9442 21.0864 17.3707
FVB/NJ m 19.3 1.1172 21.4982 17.1018
KK/HlJ f 19.33 0.79 20.8844 17.7756
KK/HlJ m 18.5 0.9442 20.3579 16.6421
LP/J f 21.0571 0.9442 22.915 19.1993
LP/J m 20.45 0.8833 22.1879 18.7121
MRL/MpJ f 25.4 1.7665 28.8757 21.9243
MRL/MpJ m 24.8 1.1172 26.9982 22.6018
NOD.B10Sn-H2b/J f 21.7571 0.9442 23.615 19.8993
NOD.B10Sn-H2b/J m 20.4 1.2491 22.8577 17.9423
NON/ShiLtJ f 18.4286 0.6677 19.7423 17.1149
NON/ShiLtJ m 16.2143 0.9442 18.0721 14.3564
NZW/LacJ f 23.62 1.1172 25.8182 21.4218
NZW/LacJ m 21.9143 0.9442 23.7721 20.0564
P/J f 18.98 1.1172 21.1782 16.7818
P/J m 21.6 1.2491 24.0577 19.1423
PL/J f 19.3 1.0199 21.3067 17.2933
PL/J m 18.85 1.2491 21.3077 16.3923
PWD/PhJ f 20.5143 0.9442 22.3721 18.6564
PWD/PhJ m 21.125 0.8833 22.8629 19.3871
RIIIS/J f 18.95 0.8833 20.6879 17.2121
RIIIS/J m 18.825 0.8833 20.5629 17.0871
SJL/J f 23.225 0.8833 24.9629 21.4871
SJL/J m 18.7833 1.0199 20.79 16.7766
SM/J f 18.1714 0.9442 20.0293 16.3136
SM/J m 22.96 1.1172 25.1582 20.7618
SWR/J f 16.5625 0.8833 18.3004 14.8246
SWR/J m 18.5667 1.0199 20.5734 16.56
WSB/EiJ f 15.9 0.8833 17.6379 14.1621
WSB/EiJ m 17.4286 0.9442 19.2864 15.5707


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 20.4643 0.6465 21.7363 19.1923
A/J both 19.4042 0.6746 20.7315 18.0768
BALB/cByJ both 20.7 0.6949 22.0673 19.3327
BTBR T+ Itpr3tf/J both 21.4467 0.7564 22.9349 19.9584
C3H/HeJ both 21.925 0.6746 23.2523 20.5977
C57BL/10J both 18.9357 0.6677 20.2494 17.622
C57BL/6J both 17.6839 0.6465 18.9559 16.4119
C57BLKS/J both 19.3214 0.6465 20.5934 18.0494
C57BR/cdJ both 17.2625 0.6246 18.4914 16.0336
C57L/J both 22.1125 0.6746 23.4398 20.7852
CBA/J both 19.5333 0.6746 20.8607 18.206
DBA/2J both 19.3229 0.7314 20.7619 17.8838
FVB/NJ both 19.2643 0.7314 20.7034 17.8252
KK/HlJ both 18.915 0.6156 20.1262 17.7038
LP/J both 20.7536 0.6465 22.0256 19.4816
MRL/MpJ both 25.1 1.0451 27.1563 23.0437
NOD.B10Sn-H2b/J both 21.0786 0.7829 22.619 19.5381
NON/ShiLtJ both 17.3214 0.5782 18.4591 16.1837
NZW/LacJ both 22.7671 0.7314 24.2062 21.3281
P/J both 20.29 0.8379 21.9387 18.6413
PL/J both 19.075 0.8063 20.6614 17.4886
PWD/PhJ both 20.8196 0.6465 22.0916 19.5477
RIIIS/J both 18.8875 0.6246 20.1164 17.6586
SJL/J both 21.0042 0.6746 22.3315 19.6768
SM/J both 20.5657 0.7314 22.0048 19.1266
SWR/J both 17.5646 0.6746 18.8919 16.2373
WSB/EiJ both 16.6643 0.6465 17.9363 15.3923




  GWAS USING LINEAR MIXED MODELS