Project measure / variable:   Yuan3   Na_M12

ID, description, units MPD:24447   Na_M12   sodium (serum Na)   [mmol/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Yuan3 - sodium (serum Na) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means155   mmol/L 156   mmol/L
Median of the strain means154   mmol/L 155   mmol/L
SD of the strain means± 5.21 ± 4.91
Coefficient of variation (CV)0.0337 0.0315
Min–max range of strain means142   –   165   mmol/L 146   –   165   mmol/L
Mean sample size per strain7.3   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 123.1942 123.1942 5.6486 0.018
strain 28 7383.1906 263.6854 12.0902 < 0.0001
sex:strain 28 3297.6298 117.7725 5.4 < 0.0001
Residuals 367 8004.1831 21.8098


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 152.0 3.25   8 1.15 0.0213 149.0, 160.0 -0.5
129S1/SvImJ m 146.0 3.89   8 1.38 0.0267 139.0, 151.0 -2.02
A/J f 153.0 4.5   6 1.84 0.0294 148.0, 159.0 -0.31
A/J m 159.0 2.91   16 0.729 0.0184 153.0, 163.0 0.62
AKR/J f 154.0 0.707   2   0.5 0.00461 153.0, 154.0 -0.12
AKR/J m 153.0 3.46   3 2.0 0.0226 151.0, 157.0 -0.6
BALB/cByJ f 154.0 3.01   8 1.06 0.0196 150.0, 158.0 -0.12
BALB/cByJ m 151.0 3.81   8 1.35 0.0252 142.0, 154.0 -1.0
BTBR T+ Itpr3tf/J f 163.0 5.44   8 1.92 0.0334 155.0, 170.0 1.61
BTBR T+ Itpr3tf/J m 163.0 5.34   7 2.02 0.0327 154.0, 169.0 1.44
BUB/BnJ f 161.0 3.79   6 1.55 0.0236 155.0, 165.0 1.23
BUB/BnJ m 155.0 4.36   9 1.45 0.0282 149.0, 162.0 -0.19
C3H/HeJ f 148.0 1.77   8 0.627 0.0119 147.0, 152.0 -1.27
C3H/HeJ m 153.0 2.21   7 0.837 0.0144 151.0, 157.0 -0.6
C57BL/10J f 147.0 3.2   8 1.13 0.0217 143.0, 154.0 -1.46
C57BL/10J m 165.0 5.05   7 1.91 0.0306 155.0, 169.0 1.85
C57BL/6J f 148.0 1.98   8 0.701 0.0134 146.0, 152.0 -1.27
C57BL/6J m 154.0 2.67   8 0.944 0.0174 150.0, 159.0 -0.39
C57BLKS/J f 161.0 5.5   8 1.95 0.0342 154.0, 169.0 1.23
C57BLKS/J m 163.0 5.9   8 2.09 0.0361 159.0, 177.0 1.44
C57BR/cdJ f 154.0 6.2   8 2.19 0.0403 144.0, 161.0 -0.12
C57BR/cdJ m 163.0 5.36   8 1.89 0.0328 157.0, 172.0 1.44
C57L/J f 154.0 6.7   7 2.53 0.0436 145.0, 163.0 -0.12
C57L/J m 150.0 5.73   8 2.03 0.0381 141.0, 156.0 -1.21
CAST/EiJ f 149.0 4.55   8 1.61 0.0306 142.0, 156.0 -1.08
CBA/J f 142.0 5.09   7 1.92 0.0358 135.0, 152.0 -2.42
CBA/J m 152.0 1.72   6 0.703 0.0113 150.0, 155.0 -0.8
DBA/2J f 152.0 6.5   6 2.65 0.0427 147.0, 165.0 -0.5
DBA/2J m 155.0 3.92   7 1.48 0.0253 149.0, 161.0 -0.19
FVB/NJ f 157.0 5.33   8 1.88 0.034 151.0, 166.0 0.46
FVB/NJ m 154.0 3.81   8 1.35 0.0248 150.0, 162.0 -0.39
KK/HlJ f 154.0 2.62   8 0.926 0.017 150.0, 158.0 -0.12
KK/HlJ m 152.0 3.55   8 1.25 0.0234 146.0, 158.0 -0.8
LP/J f 152.0 1.5   7 0.565 0.00982 151.0, 155.0 -0.5
LP/J m 151.0 4.28   8 1.51 0.0283 143.0, 157.0 -1.0
MRL/MpJ f 156.0 2.67   8 0.944 0.0171 151.0, 160.0 0.27
MRL/MpJ m 162.0 3.82   8 1.35 0.0236 155.0, 166.0 1.24
NOD.B10Sn-H2b/J f 159.0 2.28   6 0.931 0.0143 156.0, 161.0 0.84
NOD.B10Sn-H2b/J m 158.0 6.68   8 2.36 0.0423 147.0, 164.0 0.42
NON/ShiLtJ f 158.0 3.21   8 1.13 0.0202 154.0, 164.0 0.65
NON/ShiLtJ m 155.0 7.81   7 2.95 0.0504 139.0, 161.0 -0.19
NZO/HlLtJ f 153.0 5.71   7 2.16 0.0372 144.0, 160.0 -0.31
NZO/HlLtJ m 162.0 5.13   6 2.09 0.0316 154.0, 169.0 1.24
NZW/LacJ f 154.0 1.89   8 0.666 0.0122 152.0, 157.0 -0.12
NZW/LacJ m 156.0 1.77   8 0.627 0.0114 153.0, 158.0 0.01
P/J f 156.0 2.23   8 0.789 0.0143 153.0, 160.0 0.27
PL/J f 150.0 2.65   3 1.53 0.0176 148.0, 153.0 -0.88
PL/J m 151.0 2.07   5 0.927 0.0137 148.0, 153.0 -1.0
PWD/PhJ f 153.0 1.25   8 0.441 0.00814 151.0, 155.0 -0.31
PWD/PhJ m 152.0 7.47   8 2.64 0.0491 139.0, 158.0 -0.8
RIIIS/J f 165.0 5.1   8 1.8 0.031 156.0, 174.0 1.99
RIIIS/J m 160.0 8.23   8 2.91 0.0515 147.0, 170.0 0.83
SJL/J f 155.0 1.83   6 0.749 0.0119 153.0, 158.0 0.07
SJL/J m 151.0 3.77   4 1.89 0.025 148.0, 156.0 -1.0
SM/J f 159.0 1.98   7 0.747 0.0124 156.0, 161.0 0.84
SM/J m 161.0 3.09   9 1.03 0.0192 156.0, 166.0 1.03
SWR/J f 165.0 12.3   9 4.11 0.0747 154.0, 187.0 1.99
SWR/J m 159.0 3.2   7 1.21 0.0202 154.0, 163.0 0.62
WSB/EiJ f 155.0 2.7   7 1.02 0.0174 150.0, 158.0 0.07
WSB/EiJ m 156.0 4.16   7 1.57 0.0266 150.0, 161.0 0.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 152.5 1.6511 155.7469 149.2531
129S1/SvImJ m 146.0 1.6511 149.2469 142.7531
A/J f 153.3333 1.9066 157.0825 149.5842
A/J m 158.6875 1.1675 160.9834 156.3916
AKR/J f 153.5 3.3023 159.9937 147.0063
AKR/J m 153.0 2.6963 158.3021 147.6979
BALB/cByJ f 153.75 1.6511 156.9969 150.5031
BALB/cByJ m 151.25 1.6511 154.4969 148.0031
BTBR T+ Itpr3tf/J f 163.25 1.6511 166.4969 160.0031
BTBR T+ Itpr3tf/J m 163.1429 1.7651 166.6139 159.6718
BUB/BnJ f 161.0 1.9066 164.7491 157.2509
BUB/BnJ m 154.6667 1.5567 157.7278 151.6055
C3H/HeJ f 148.5 1.6511 151.7469 145.2531
C3H/HeJ m 153.2857 1.7651 156.7568 149.8147
C57BL/10J f 147.375 1.6511 150.6219 144.1281
C57BL/10J m 165.1429 1.7651 168.6139 161.6718
C57BL/6J f 148.25 1.6511 151.4969 145.0031
C57BL/6J m 153.625 1.6511 156.8719 150.3781
C57BLKS/J f 161.0 1.6511 164.2469 157.7531
C57BLKS/J m 163.375 1.6511 166.6219 160.1281
C57BR/cdJ f 153.875 1.6511 157.1219 150.6281
C57BR/cdJ m 163.125 1.6511 166.3719 159.8781
C57L/J f 153.7143 1.7651 157.1853 150.2432
C57L/J m 150.5 1.6511 153.7469 147.2531
CBA/J f 142.2857 1.7651 145.7568 138.8147
CBA/J m 152.1667 1.9066 155.9158 148.4175
DBA/2J f 152.3333 1.9066 156.0825 148.5842
DBA/2J m 155.0 1.7651 158.471 151.529
FVB/NJ f 156.875 1.6511 160.1219 153.6281
FVB/NJ m 153.625 1.6511 156.8719 150.3781
KK/HlJ f 154.0 1.6511 157.2469 150.7531
KK/HlJ m 151.5 1.6511 154.7469 148.2531
LP/J f 152.2857 1.7651 155.7568 148.8147
LP/J m 151.0 1.6511 154.2469 147.7531
MRL/MpJ f 156.375 1.6511 159.6219 153.1281
MRL/MpJ m 162.0 1.6511 165.2469 158.7531
NOD.B10Sn-H2b/J f 159.0 1.9066 162.7491 155.2509
NOD.B10Sn-H2b/J m 158.0 1.6511 161.2469 154.7531
NON/ShiLtJ f 158.5 1.6511 161.7469 155.2531
NON/ShiLtJ m 155.0 1.7651 158.471 151.529
NZO/HlLtJ f 153.2857 1.7651 156.7568 149.8147
NZO/HlLtJ m 162.3333 1.9066 166.0825 158.5842
NZW/LacJ f 154.125 1.6511 157.3719 150.8781
NZW/LacJ m 155.5 1.6511 158.7469 152.2531
PL/J f 150.0 2.6963 155.3021 144.6979
PL/J m 151.4 2.0885 155.507 147.293
PWD/PhJ f 153.125 1.6511 156.3719 149.8781
PWD/PhJ m 152.125 1.6511 155.3719 148.8781
RIIIS/J f 164.625 1.6511 167.8719 161.3781
RIIIS/J m 159.625 1.6511 162.8719 156.3781
SJL/J f 154.8333 1.9066 158.5825 151.0842
SJL/J m 150.75 2.335 155.3417 146.1583
SM/J f 159.2857 1.7651 162.7568 155.8147
SM/J m 160.5556 1.5567 163.6167 157.4944
SWR/J f 164.8889 1.5567 167.9501 161.8277
SWR/J m 158.7143 1.7651 162.1853 155.2432
WSB/EiJ f 155.4286 1.7651 158.8996 151.9575
WSB/EiJ m 156.4286 1.7651 159.8996 152.9575


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 149.25 1.1675 151.5459 146.9541
A/J both 156.0104 1.1178 158.2085 153.8123
AKR/J both 153.25 2.1316 157.4417 149.0583
BALB/cByJ both 152.5 1.1675 154.7959 150.2041
BTBR T+ Itpr3tf/J both 163.1964 1.2085 165.5729 160.82
BUB/BnJ both 157.8333 1.2307 160.2534 155.4133
C3H/HeJ both 150.8929 1.2085 153.2693 148.5164
C57BL/10J both 156.2589 1.2085 158.6354 153.8825
C57BL/6J both 150.9375 1.1675 153.2334 148.6416
C57BLKS/J both 162.1875 1.1675 164.4834 159.8916
C57BR/cdJ both 158.5 1.1675 160.7959 156.2041
C57L/J both 152.1071 1.2085 154.4836 149.7307
CBA/J both 147.2262 1.2991 149.7808 144.6716
DBA/2J both 153.6667 1.2991 156.2213 151.1121
FVB/NJ both 155.25 1.1675 157.5459 152.9541
KK/HlJ both 152.75 1.1675 155.0459 150.4541
LP/J both 151.6429 1.2085 154.0193 149.2664
MRL/MpJ both 159.1875 1.1675 161.4834 156.8916
NOD.B10Sn-H2b/J both 158.5 1.2611 160.9798 156.0202
NON/ShiLtJ both 156.75 1.2085 159.1265 154.3735
NZO/HlLtJ both 157.8095 1.2991 160.3641 155.2549
NZW/LacJ both 154.8125 1.1675 157.1084 152.5166
PL/J both 150.7 1.7053 154.0533 147.3467
PWD/PhJ both 152.625 1.1675 154.9209 150.3291
RIIIS/J both 162.125 1.1675 164.4209 159.8291
SJL/J both 152.7917 1.5073 155.7556 149.8277
SM/J both 159.9206 1.1768 162.2347 157.6066
SWR/J both 161.8016 1.1768 164.1156 159.4876
WSB/EiJ both 155.9286 1.2481 158.383 153.4742




  GWAS USING LINEAR MIXED MODELS