Project measure / variable:   Yuan3   K_M12

ID, description, units MPD:24442   K_M12   potassium (serum K)   [mmol/L]  at age 12mo  
Data set, strains Yuan3   inbred   31 strains     sex: both     age: 52wks
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  STRAIN COMPARISON PLOT
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Yuan3 - potassium (serum K) at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains29 strains
Mean of the strain means6.22   mmol/L 6.41   mmol/L
Median of the strain means6.15   mmol/L 6.35   mmol/L
SD of the strain means± 0.519 ± 0.501
Coefficient of variation (CV)0.0834 0.0781
Min–max range of strain means5.35   –   7.38   mmol/L 5.53   –   7.39   mmol/L
Mean sample size per strain7.3   mice 7.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5.7086 5.7086 17.4019 < 0.0001
strain 28 108.7713 3.8847 11.842 < 0.0001
sex:strain 28 12.2309 0.4368 1.3316 0.1245
Residuals 366 120.0639 0.328


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.43 0.356   8 0.126 0.0656 4.93, 5.99 -1.53
129S1/SvImJ m 5.53 0.32   8 0.113 0.0578 5.13, 6.07 -1.76
A/J f 6.2 0.524   6 0.214 0.0845 5.73, 7.09 -0.04
A/J m 7.31 0.575   16 0.144 0.0787 6.41, 8.31 1.79
AKR/J f 6.15 0.382   2   0.27 0.0621 5.88, 6.42 -0.14
AKR/J m 6.58 0.68   3 0.392 0.103 6.03, 7.34 0.33
BALB/cByJ f 6.2 0.517   8 0.183 0.0834 5.23, 6.99 -0.04
BALB/cByJ m 6.79 0.934   8 0.33 0.137 5.21, 7.91 0.75
BTBR T+ Itpr3tf/J f 6.6 0.424   8 0.15 0.0643 5.87, 7.23 0.73
BTBR T+ Itpr3tf/J m 6.35 0.612   7 0.231 0.0963 5.63, 7.35 -0.13
BUB/BnJ f 5.82 0.294   6 0.12 0.0506 5.48, 6.26 -0.78
BUB/BnJ m 5.73 0.337   9 0.112 0.0588 5.14, 6.22 -1.36
C3H/HeJ f 5.35 0.281   8 0.0994 0.0526 4.93, 5.83 -1.68
C3H/HeJ m 5.91 0.462   7 0.174 0.0782 5.23, 6.53 -1.0
C57BL/10J f 6.13 0.358   8 0.127 0.0585 5.67, 6.75 -0.18
C57BL/10J m 6.99 0.315   7 0.119 0.045 6.55, 7.43 1.15
C57BL/6J f 5.51 0.39   8 0.138 0.0707 4.97, 6.15 -1.37
C57BL/6J m 5.62 0.6   8 0.212 0.107 4.66, 6.58 -1.58
C57BLKS/J f 6.05 0.884   8 0.313 0.146 4.42, 7.34 -0.33
C57BLKS/J m 5.93 0.361   8 0.128 0.0609 5.47, 6.43 -0.96
C57BR/cdJ f 6.15 0.707   8 0.25 0.115 5.22, 7.12 -0.14
C57BR/cdJ m 6.28 0.864   8 0.305 0.138 5.05, 7.91 -0.27
C57L/J f 6.09 0.419   7 0.159 0.0689 5.76, 6.84 -0.26
C57L/J m 6.3 0.532   8 0.188 0.0844 5.62, 7.08 -0.23
CAST/EiJ f 6.43 0.632   8 0.224 0.0984 5.5, 7.61 0.4
CBA/J f 5.62 0.372   7 0.141 0.0663 5.12, 6.12 -1.16
CBA/J m 6.25 0.347   6 0.142 0.0556 5.84, 6.76 -0.33
DBA/2J f 6.7 1.07   6 0.436 0.159 5.9, 8.84 0.92
DBA/2J m 6.88 0.562   7 0.212 0.0817 5.79, 7.45 0.93
FVB/NJ f 7.27 0.814   8 0.288 0.112 5.99, 8.33 2.02
FVB/NJ m 7.36 0.551   8 0.195 0.0748 6.72, 8.48 1.89
KK/HlJ f 5.98 0.352   8 0.125 0.0589 5.41, 6.55 -0.47
KK/HlJ m 5.81 0.614   8 0.217 0.106 5.14, 6.96 -1.2
LP/J f 5.8 0.438   7 0.166 0.0756 5.01, 6.37 -0.82
LP/J m 6.47 0.493   8 0.174 0.0762 5.94, 7.38 0.11
MRL/MpJ f 6.18 0.741   8 0.262 0.12 5.16, 7.48 -0.08
MRL/MpJ m 6.31 0.649   8 0.23 0.103 5.35, 7.31 -0.21
NOD.B10Sn-H2b/J f 6.42 0.412   6 0.168 0.0642 5.94, 6.96 0.38
NOD.B10Sn-H2b/J m 6.77 0.35   7 0.132 0.0517 6.34, 7.24 0.71
NON/ShiLtJ f 7.11 1.14   8 0.404 0.161 5.53, 8.89 1.71
NON/ShiLtJ m 6.74 0.608   7 0.23 0.0903 5.99, 7.67 0.65
NZO/HlLtJ f 6.08 0.589   7 0.223 0.0969 5.18, 7.14 -0.28
NZO/HlLtJ m 6.19 0.349   6 0.142 0.0564 5.75, 6.63 -0.45
NZW/LacJ f 6.47 0.385   8 0.136 0.0595 6.03, 7.23 0.48
NZW/LacJ m 6.48 0.781   8 0.276 0.121 5.64, 7.88 0.13
P/J f 6.87 0.598   8 0.211 0.0871 5.83, 7.49 1.25
PL/J f 6.39 0.151   3 0.0874 0.0237 6.28, 6.56 0.32
PL/J m 6.61 0.406   5 0.182 0.0614 6.08, 7.02 0.39
PWD/PhJ f 5.58 0.409   8 0.145 0.0734 4.95, 6.33 -1.24
PWD/PhJ m 6.02 0.382   8 0.135 0.0634 5.41, 6.63 -0.79
RIIIS/J f 6.95 0.832   8 0.294 0.12 5.85, 8.35 1.4
RIIIS/J m 6.83 0.44   8 0.156 0.0644 6.27, 7.61 0.83
SJL/J f 6.18 0.35   6 0.143 0.0567 5.71, 6.63 -0.08
SJL/J m 6.36 0.393   4 0.196 0.0617 5.91, 6.85 -0.11
SM/J f 5.97 0.327   7 0.124 0.0548 5.57, 6.51 -0.49
SM/J m 6.11 0.476   9 0.159 0.0779 5.45, 6.81 -0.61
SWR/J f 7.38 0.714   9 0.238 0.0968 6.22, 8.43 2.23
SWR/J m 7.39 0.794   7 0.3 0.107 6.4, 8.6 1.95
WSB/EiJ f 5.86 0.507   7 0.192 0.0866 5.17, 6.59 -0.7
WSB/EiJ m 6.09 0.456   7 0.172 0.0749 5.39, 6.79 -0.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.43 0.2025 5.8282 5.0318
129S1/SvImJ m 5.535 0.2025 5.9332 5.1368
A/J f 6.1967 0.2338 6.6565 5.7369
A/J m 7.3075 0.1432 7.5891 7.0259
AKR/J f 6.15 0.405 6.9464 5.3536
AKR/J m 6.58 0.3307 7.2303 5.9297
BALB/cByJ f 6.2 0.2025 6.5982 5.8018
BALB/cByJ m 6.7925 0.2025 7.1907 6.3943
BTBR T+ Itpr3tf/J f 6.6025 0.2025 7.0007 6.2043
BTBR T+ Itpr3tf/J m 6.3529 0.2165 6.7786 5.9272
BUB/BnJ f 5.8167 0.2338 6.2765 5.3569
BUB/BnJ m 5.7344 0.1909 6.1099 5.359
C3H/HeJ f 5.345 0.2025 5.7432 4.9468
C3H/HeJ m 5.9071 0.2165 6.3328 5.4814
C57BL/10J f 6.13 0.2025 6.5282 5.7318
C57BL/10J m 6.9871 0.2165 7.4128 6.5614
C57BL/6J f 5.51 0.2025 5.9082 5.1118
C57BL/6J m 5.6175 0.2025 6.0157 5.2193
C57BLKS/J f 6.0475 0.2025 6.4457 5.6493
C57BLKS/J m 5.9275 0.2025 6.3257 5.5293
C57BR/cdJ f 6.1525 0.2025 6.5507 5.7543
C57BR/cdJ m 6.2775 0.2025 6.6757 5.8793
C57L/J f 6.0857 0.2165 6.5114 5.66
C57L/J m 6.3 0.2025 6.6982 5.9018
CBA/J f 5.62 0.2165 6.0457 5.1943
CBA/J m 6.2467 0.2338 6.7065 5.7869
DBA/2J f 6.6967 0.2338 7.1565 6.2369
DBA/2J m 6.8814 0.2165 7.3071 6.4557
FVB/NJ f 7.2725 0.2025 7.6707 6.8743
FVB/NJ m 7.3625 0.2025 7.7607 6.9643
KK/HlJ f 5.9825 0.2025 6.3807 5.5843
KK/HlJ m 5.8075 0.2025 6.2057 5.4093
LP/J f 5.7957 0.2165 6.2214 5.37
LP/J m 6.47 0.2025 6.8682 6.0718
MRL/MpJ f 6.1775 0.2025 6.5757 5.7793
MRL/MpJ m 6.315 0.2025 6.7132 5.9168
NOD.B10Sn-H2b/J f 6.42 0.2338 6.8798 5.9602
NOD.B10Sn-H2b/J m 6.7743 0.2165 7.2 6.3486
NON/ShiLtJ f 7.11 0.2025 7.5082 6.7118
NON/ShiLtJ m 6.7386 0.2165 7.1643 6.3129
NZO/HlLtJ f 6.08 0.2165 6.5057 5.6543
NZO/HlLtJ m 6.1933 0.2338 6.6531 5.7335
NZW/LacJ f 6.4725 0.2025 6.8707 6.0743
NZW/LacJ m 6.4775 0.2025 6.8757 6.0793
PL/J f 6.3867 0.3307 7.0369 5.7364
PL/J m 6.612 0.2561 7.1157 6.1083
PWD/PhJ f 5.5775 0.2025 5.9757 5.1793
PWD/PhJ m 6.0225 0.2025 6.4207 5.6243
RIIIS/J f 6.9475 0.2025 7.3457 6.5493
RIIIS/J m 6.8325 0.2025 7.2307 6.4343
SJL/J f 6.1767 0.2338 6.6365 5.7169
SJL/J m 6.365 0.2864 6.9281 5.8019
SM/J f 5.9671 0.2165 6.3928 5.5414
SM/J m 6.1122 0.1909 6.4877 5.7368
SWR/J f 7.3756 0.1909 7.751 7.0001
SWR/J m 7.3914 0.2165 7.8171 6.9657
WSB/EiJ f 5.8586 0.2165 6.2843 5.4329
WSB/EiJ m 6.09 0.2165 6.5157 5.6643


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.4825 0.1432 5.7641 5.2009
A/J both 6.7521 0.1371 7.0217 6.4825
AKR/J both 6.365 0.2614 6.8791 5.8509
BALB/cByJ both 6.4962 0.1432 6.7778 6.2147
BTBR T+ Itpr3tf/J both 6.4777 0.1482 6.7691 6.1862
BUB/BnJ both 5.7756 0.1509 6.0724 5.4788
C3H/HeJ both 5.6261 0.1482 5.9175 5.3346
C57BL/10J both 6.5586 0.1482 6.85 6.2671
C57BL/6J both 5.5637 0.1432 5.8453 5.2822
C57BLKS/J both 5.9875 0.1432 6.2691 5.7059
C57BR/cdJ both 6.215 0.1432 6.4966 5.9334
C57L/J both 6.1929 0.1482 6.4843 5.9014
CBA/J both 5.9333 0.1593 6.2466 5.62
DBA/2J both 6.789 0.1593 7.1024 6.4757
FVB/NJ both 7.3175 0.1432 7.5991 7.0359
KK/HlJ both 5.895 0.1432 6.1766 5.6134
LP/J both 6.1329 0.1482 6.4243 5.8414
MRL/MpJ both 6.2462 0.1432 6.5278 5.9647
NOD.B10Sn-H2b/J both 6.5971 0.1593 6.9104 6.2838
NON/ShiLtJ both 6.9243 0.1482 7.2157 6.6328
NZO/HlLtJ both 6.1367 0.1593 6.45 5.8234
NZW/LacJ both 6.475 0.1432 6.7566 6.1934
PL/J both 6.4993 0.2091 6.9106 6.0881
PWD/PhJ both 5.8 0.1432 6.0816 5.5184
RIIIS/J both 6.89 0.1432 7.1716 6.6084
SJL/J both 6.2708 0.1849 6.6343 5.9073
SM/J both 6.0397 0.1443 6.3235 5.7559
SWR/J both 7.3835 0.1443 7.6673 7.0997
WSB/EiJ both 5.9743 0.1531 6.2753 5.6733




  GWAS USING LINEAR MIXED MODELS