Phenotype measure:   Yuan3   Cl_M18

ID, description, units MPD:24423   Cl_M18   chloride (serum Cl)   [mmol/L]  at age 18mo
Data set, strains Yuan3   inbred   29 strains     sex: both     age: 78wks
Procedure metabolic panel
Ontology mappings

  STRAIN COMPARISON PLOT
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Yuan3 - chloride (serum Cl) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains28 strains
Mean of the strain means116   mmol/L 115   mmol/L
Median of the strain means115   mmol/L 116   mmol/L
SD of the strain means± 3.64 ± 4.99
Coefficient of variation (CV)0.0314 0.0434
Min–max range of strain means110   –   125   mmol/L 101   –   124   mmol/L
Mean sample size per strain7.1   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 102.086 102.086 7.1433 0.0079
strain 26 4390.6886 168.8726 11.8166 < 0.0001
sex:strain 26 1762.4944 67.7882 4.7434 < 0.0001
Residuals 315 4501.6944 14.2911


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 115.0 3.44   7 1.3 0.0298 110.0, 120.0 -0.26
129S1/SvImJ m 112.0 3.0   8 1.06 0.0268 108.0, 117.0 -0.59
A/J f 119.0 3.33   8 1.18 0.0279 113.0, 123.0 0.84
A/J m 124.0 4.17   6 1.7 0.0336 118.0, 129.0 1.82
BALB/cByJ f 119.0 3.13   7 1.18 0.0264 115.0, 123.0 0.84
BALB/cByJ m 122.0 1.37   6 0.558 0.0112 121.0, 124.0 1.42
BTBR T+ Itpr3tf/J f 115.0 2.56   6 1.05 0.0223 112.0, 118.0 -0.26
BTBR T+ Itpr3tf/J m 114.0 1.1   5 0.49 0.00959 113.0, 116.0 -0.19
BUB/BnJ f 118.0 3.81   5 1.7 0.0323 114.0, 124.0 0.57
C3H/HeJ f 116.0 3.73   6 1.52 0.0323 113.0, 122.0 0.02
C3H/HeJ m 118.0 3.23   8 1.14 0.0274 113.0, 122.0 0.62
C57BL/10J f 114.0 3.3   7 1.25 0.029 110.0, 118.0 -0.53
C57BL/10J m 116.0 2.5   7 0.944 0.0216 112.0, 120.0 0.21
C57BL/6J f 115.0 2.67   8 0.945 0.0232 112.0, 121.0 -0.26
C57BL/6J m 116.0 3.15   7 1.19 0.0271 111.0, 120.0 0.21
C57BLKS/J f 120.0 3.65   7 1.38 0.0304 116.0, 127.0 1.12
C57BLKS/J m 115.0 2.2   8 0.778 0.0192 111.0, 118.0 0.01
C57BR/cdJ f 120.0 2.73   8 0.964 0.0228 116.0, 123.0 1.12
C57BR/cdJ m 120.0 1.98   8 0.701 0.0165 117.0, 123.0 1.02
C57L/J f 121.0 3.69   8 1.31 0.0305 115.0, 128.0 1.39
C57L/J m 110.0 2.88   6 1.17 0.0262 106.0, 114.0 -0.99
CBA/J f 114.0 2.38   8 0.84 0.0208 110.0, 117.0 -0.53
CBA/J m 113.0 2.34   6 0.955 0.0206 110.0, 116.0 -0.39
DBA/2J f 113.0 2.0   5 0.894 0.0177 110.0, 115.0 -0.8
DBA/2J m 114.0 1.89   8 0.666 0.0165 112.0, 116.0 -0.19
FVB/NJ f 114.0 2.73   8 0.964 0.0238 109.0, 118.0 -0.53
FVB/NJ m 116.0 2.12   5 0.949 0.0183 114.0, 119.0 0.21
KK/HlJ f 113.0 9.29   9 3.1 0.0822 102.0, 127.0 -0.8
KK/HlJ m 116.0 3.53   7 1.34 0.0305 109.0, 120.0 0.21
LP/J f 114.0 3.5   7 1.32 0.0308 108.0, 119.0 -0.53
LP/J m 110.0 2.33   8 0.824 0.0211 107.0, 114.0 -0.99
MRL/MpJ f 110.0 9.19   2   6.5 0.0832 104.0, 117.0 -1.63
MRL/MpJ m 117.0 3.74   5 1.67 0.032 112.0, 122.0 0.42
NOD.B10Sn-H2b/J f 118.0 2.48   7 0.937 0.021 115.0, 122.0 0.57
NOD.B10Sn-H2b/J m 111.0 0.957   4 0.479 0.00861 110.0, 112.0 -0.79
NON/ShiLtJ f 121.0 6.99   14 1.87 0.0579 111.0, 133.0 1.39
NON/ShiLtJ m 119.0 7.11   7 2.69 0.0599 103.0, 124.0 0.82
NZO/HlLtJ f 112.0 7.86   9 2.62 0.0705 100.0, 120.0 -1.08
NZO/HlLtJ m 113.0 0.0   1   0.0 0.0 113.0, 113.0 -0.39
NZW/LacJ f 112.0 3.27   5 1.46 0.0292 109.0, 117.0 -1.08
NZW/LacJ m 111.0 1.95   7 0.738 0.0176 108.0, 114.0 -0.79
P/J f 119.0 2.55   5 1.14 0.0214 116.0, 122.0 0.84
P/J m 101.0 3.38   4 1.69 0.0334 97.7, 105.0 -2.79
PL/J f 110.0 8.69   7 3.28 0.0791 100.0, 120.0 -1.63
PL/J m 107.0 0.5   4 0.25 0.00468 106.0, 107.0 -1.59
PWD/PhJ f 112.0 2.23   7 0.841 0.0199 108.0, 114.0 -1.08
PWD/PhJ m 112.0 2.71   8 0.959 0.0243 108.0, 115.0 -0.59
RIIIS/J f 116.0 2.64   8 0.934 0.0228 113.0, 121.0 0.02
RIIIS/J m 117.0 1.81   8 0.639 0.0155 113.0, 119.0 0.42
SJL/J f 119.0 4.07   8 1.44 0.0343 112.0, 123.0 0.84
SJL/J m 119.0 1.47   6 0.601 0.0124 117.0, 121.0 0.82
SM/J f 114.0 3.55   7 1.34 0.0313 110.0, 120.0 -0.53
SM/J m 113.0 2.28   5 1.02 0.0202 110.0, 116.0 -0.39
SWR/J f 114.0 4.57   8 1.61 0.0399 109.0, 120.0 -0.53
SWR/J m 118.0 2.73   6 1.12 0.0232 115.0, 122.0 0.62
WSB/EiJ f 125.0 2.7   8 0.953 0.0216 122.0, 131.0 2.49
WSB/EiJ m 124.0 2.87   7 1.08 0.0232 119.0, 127.0 1.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 115.1429 1.4288 117.9541 112.3316
129S1/SvImJ m 111.875 1.3366 114.5047 109.2453
A/J f 119.25 1.3366 121.8797 116.6203
A/J m 124.1667 1.5433 127.2032 121.1301
BALB/cByJ f 118.8571 1.4288 121.6684 116.0459
BALB/cByJ m 122.3333 1.5433 125.3699 119.2968
BTBR T+ Itpr3tf/J f 115.1667 1.5433 118.2032 112.1301
BTBR T+ Itpr3tf/J m 114.2 1.6906 117.5263 110.8737
C3H/HeJ f 115.5 1.5433 118.5365 112.4635
C3H/HeJ m 117.875 1.3366 120.5047 115.2453
C57BL/10J f 113.7143 1.4288 116.5256 110.903
C57BL/10J m 115.7143 1.4288 118.5256 112.903
C57BL/6J f 115.0 1.3366 117.6297 112.3703
C57BL/6J m 116.2857 1.4288 119.097 113.4744
C57BLKS/J f 120.0 1.4288 122.8113 117.1887
C57BLKS/J m 114.625 1.3366 117.2547 111.9953
C57BR/cdJ f 119.5 1.3366 122.1297 116.8703
C57BR/cdJ m 120.25 1.3366 122.8797 117.6203
C57L/J f 121.25 1.3366 123.8797 118.6203
C57L/J m 109.6667 1.5433 112.7032 106.6301
CBA/J f 114.25 1.3366 116.8797 111.6203
CBA/J m 113.3333 1.5433 116.3699 110.2968
DBA/2J f 113.0 1.6906 116.3263 109.6737
DBA/2J m 114.125 1.3366 116.7547 111.4953
FVB/NJ f 114.5 1.3366 117.1297 111.8703
FVB/NJ m 116.0 1.6906 119.3263 112.6737
KK/HlJ f 113.1111 1.2601 115.5904 110.6318
KK/HlJ m 115.8571 1.4288 118.6684 113.0459
LP/J f 113.7143 1.4288 116.5256 110.903
LP/J m 110.5 1.3366 113.1297 107.8703
MRL/MpJ f 110.5 2.6731 115.7594 105.2406
MRL/MpJ m 117.0 1.6906 120.3263 113.6737
NOD.B10Sn-H2b/J f 117.8571 1.4288 120.6684 115.0459
NOD.B10Sn-H2b/J m 111.25 1.8902 114.969 107.531
NON/ShiLtJ f 120.6429 1.0103 122.6307 118.655
NON/ShiLtJ m 118.7143 1.4288 121.5256 115.903
NZW/LacJ f 112.2 1.6906 115.5263 108.8737
NZW/LacJ m 110.8571 1.4288 113.6684 108.0459
P/J f 119.0 1.6906 122.3263 115.6737
P/J m 101.2 1.8902 104.919 97.481
PL/J f 109.8571 1.4288 112.6684 107.0459
PL/J m 106.75 1.8902 110.469 103.031
PWD/PhJ f 111.5714 1.4288 114.3827 108.7602
PWD/PhJ m 111.75 1.3366 114.3797 109.1203
RIIIS/J f 115.875 1.3366 118.5047 113.2453
RIIIS/J m 116.875 1.3366 119.5047 114.2453
SJL/J f 118.625 1.3366 121.2547 115.9953
SJL/J m 119.1667 1.5433 122.2032 116.1301
SM/J f 113.5714 1.4288 116.3827 110.7602
SM/J m 112.8 1.6906 116.1263 109.4737
SWR/J f 114.375 1.3366 117.0047 111.7453
SWR/J m 117.6667 1.5433 120.7032 114.6301
WSB/EiJ f 124.875 1.3366 127.5047 122.2453
WSB/EiJ m 123.7143 1.4288 126.5256 120.903


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 113.5089 0.9783 115.4337 111.5842
A/J both 121.7083 1.0208 123.7168 119.6999
BALB/cByJ both 120.5952 1.0516 122.6643 118.5262
BTBR T+ Itpr3tf/J both 114.6833 1.1446 116.9353 112.4314
C3H/HeJ both 116.6875 1.0208 118.696 114.679
C57BL/10J both 114.7143 1.0103 116.7022 112.7264
C57BL/6J both 115.6429 0.9783 117.5676 113.7181
C57BLKS/J both 117.3125 0.9783 119.2372 115.3878
C57BR/cdJ both 119.875 0.9451 121.7345 118.0155
C57L/J both 115.4583 1.0208 117.4668 113.4499
CBA/J both 113.7917 1.0208 115.8001 111.7832
DBA/2J both 113.5625 1.0776 115.6826 111.4424
FVB/NJ both 115.25 1.0776 117.3701 113.1299
KK/HlJ both 114.4841 0.9526 116.3583 112.6099
LP/J both 112.1071 0.9783 114.0319 110.1824
MRL/MpJ both 113.75 1.5814 116.8615 110.6385
NOD.B10Sn-H2b/J both 114.5536 1.1847 116.8846 112.2226
NON/ShiLtJ both 119.6786 0.875 121.4001 117.957
NZW/LacJ both 111.5286 1.1068 113.7062 109.351
P/J both 110.1 1.268 112.5948 107.6052
PL/J both 108.3036 1.1847 110.6346 105.9726
PWD/PhJ both 111.6607 0.9783 113.5855 109.736
RIIIS/J both 116.375 0.9451 118.2345 114.5155
SJL/J both 118.8958 1.0208 120.9043 116.8874
SM/J both 113.1857 1.1068 115.3633 111.0081
SWR/J both 116.0208 1.0208 118.0293 114.0124
WSB/EiJ both 124.2946 0.9783 126.2194 122.3699




  GWAS USING LINEAR MIXED MODELS