Project measure / variable:   Petkova1   CD8_effector_M24

ID, description, units MPD:24274   CD8_effector_M24   CD8 T cells, effector, as percentage of total CD8 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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Petkova1 - CD8 T cells, effector, as percentage of total CD8 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means21.9   % 17.0   %
Median of the strain means20.7   % 15.1   %
SD of the strain means± 13.1 ± 12.6
Coefficient of variation (CV)0.599 0.741
Min–max range of strain means6.07   –   48.4   % 3.07   –   41.4   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 60.7356 60.7356 0.8115 0.3695
strain 9 8802.787 978.0874 13.0682 < 0.0001
sex:strain 9 6879.0305 764.3367 10.2122 < 0.0001
Residuals 121 9056.2584 74.8451


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 6.07 3.59   6 1.47 0.592 2.79, 11.9 -1.21
129S1/SvImJ m 41.4 8.05   7 3.04 0.194 34.1, 57.3 1.93
BALB/cByJ f 48.4 26.3   7 9.94 0.544 22.9, 90.8 2.01
C3H/HeJ m 3.07 1.67   8 0.59 0.544 0.55, 5.74 -1.11
C57BL/10J f 11.9 8.63   8 3.05 0.723 3.02, 26.7 -0.76
C57BL/10J m 5.19 3.0   6 1.22 0.577 2.49, 10.3 -0.94
C57BL/6J f 13.4 5.98   8 2.11 0.447 3.55, 21.5 -0.65
C57BL/6J m 16.3 9.94   8 3.51 0.61 6.55, 30.2 -0.06
C57BLKS/J f 11.8 6.15   6 2.51 0.52 5.34, 23.1 -0.77
C57BLKS/J m 5.75 3.1   7 1.17 0.538 1.27, 9.82 -0.89
C57BR/cdJ f 35.9 9.16   7 3.46 0.255 19.9, 46.4 1.06
C57BR/cdJ m 12.8 7.88   9 2.63 0.618 1.32, 26.8 -0.33
LP/J f 25.9 15.7   8 5.56 0.608 3.24, 59.2 0.3
LP/J m 32.4 12.9   6 5.26 0.398 22.9, 58.0 1.22
NON/ShiLtJ f 20.7 7.39   8 2.61 0.357 11.4, 29.7 -0.09
NON/ShiLtJ m 15.1 10.5   7 3.98 0.698 6.58, 32.5 -0.15
NZW/LacJ f 8.62 7.77   6 3.17 0.901 2.93, 23.7 -1.01
NZW/LacJ m 5.72 1.91   7 0.72 0.333 4.05, 8.59 -0.9
PWD/PhJ f 28.6 6.84   7 2.59 0.239 22.0, 42.3 0.51
PWD/PhJ m 20.8 9.73   7 3.68 0.467 4.38, 33.7 0.3
WSB/EiJ f 30.0 11.1   6 4.53 0.37 18.4, 47.0 0.61
WSB/EiJ m 28.6 8.63   7 3.26 0.302 14.6, 41.5 0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 6.0683 3.5319 13.0606 0.0
129S1/SvImJ m 41.3714 3.2699 47.845 34.8978
C57BL/10J f 11.9362 3.0587 17.9918 5.8807
C57BL/10J m 5.1917 3.5319 12.184 0.0
C57BL/6J f 13.3663 3.0587 19.4218 7.3107
C57BL/6J m 16.2863 3.0587 22.3418 10.2307
C57BLKS/J f 11.8183 3.5319 18.8106 4.826
C57BLKS/J m 5.7529 3.2699 12.2265 0.0
C57BR/cdJ f 35.8714 3.2699 42.345 29.3978
C57BR/cdJ m 12.75 2.8838 18.4592 7.0408
LP/J f 25.8925 3.0587 31.948 19.837
LP/J m 32.35 3.5319 39.3423 25.3577
NON/ShiLtJ f 20.7 3.0587 26.7555 14.6445
NON/ShiLtJ m 15.11 3.2699 21.5836 8.6364
NZW/LacJ f 8.625 3.5319 15.6173 1.6327
NZW/LacJ m 5.7186 3.2699 12.1922 0.0
PWD/PhJ f 28.5857 3.2699 35.0593 22.1121
PWD/PhJ m 20.8257 3.2699 27.2993 14.3521
WSB/EiJ f 30.0333 3.5319 37.0256 23.041
WSB/EiJ m 28.6 3.2699 35.0736 22.1264


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 23.7199 2.4066 28.4843 18.9554
C57BL/10J both 8.564 2.3361 13.1889 3.939
C57BL/6J both 14.8263 2.1628 19.1081 10.5444
C57BLKS/J both 8.7856 2.4066 13.55 4.0212
C57BR/cdJ both 24.3107 2.1799 28.6264 19.995
LP/J both 29.1212 2.3361 33.7462 24.4963
NON/ShiLtJ both 17.905 2.2387 22.3372 13.4728
NZW/LacJ both 7.1718 2.4066 11.9362 2.4073
PWD/PhJ both 24.7057 2.3122 29.2832 20.1282
WSB/EiJ both 29.3167 2.4066 34.0811 24.5522




  GWAS USING LINEAR MIXED MODELS