Project measure / variable:   Petkova1   CD8_effector_M18

ID, description, units MPD:24273   CD8_effector_M18   CD8 T cells, effector, as percentage of total CD8 T cells   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, effector, as percentage of total CD8 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means17.7   % 20.7   %
Median of the strain means15.5   % 11.1   %
SD of the strain means± 15.0 ± 20.7
Coefficient of variation (CV)0.849 0.999
Min–max range of strain means2.74   –   83.7   % 2.62   –   81.7   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 318.1813 318.1813 1.774 0.184
strain 22 95411.4695 4336.885 24.1797 < 0.0001
sex:strain 22 17647.9316 802.1787 4.4724 < 0.0001
Residuals 278 49862.1708 179.3603


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 12.9 3.77   7 1.42 0.293 8.49, 17.3 -0.32
129S1/SvImJ m 17.2 5.8   8 2.05 0.336 11.1, 29.2 -0.17
A/J f 10.1 3.74   8 1.32 0.372 6.13, 15.9 -0.51
BALB/cByJ f 17.5 4.9   8 1.73 0.28 6.7, 22.5 -0.01
BALB/cByJ m 47.2 15.0   6 6.11 0.317 19.5, 64.2 1.28
BTBR T+ Itpr3tf/J f 3.88 1.87   8 0.661 0.483 2.26, 7.89 -0.92
BTBR T+ Itpr3tf/J m 4.75 2.73   5 1.22 0.574 1.68, 8.53 -0.77
BUB/BnJ f 2.74 1.72   8 0.608 0.627 0.8, 5.27 -1.0
BUB/BnJ m 10.8 6.11   6 2.5 0.564 4.3, 22.2 -0.48
C3H/HeJ f 4.2 1.06   8 0.374 0.252 2.73, 5.73 -0.9
C3H/HeJ m 5.74 2.12   8 0.75 0.37 2.44, 9.08 -0.72
C57BL/10J f 17.1 8.27   7 3.12 0.484 7.99, 32.5 -0.04
C57BL/10J m 6.78 0.0   1   0.0 0.0 6.78, 6.78 -0.67
C57BL/6J f 8.47 4.76   8 1.68 0.562 4.67, 17.6 -0.61
C57BL/6J m 10.5 4.18   7 1.58 0.4 4.94, 16.6 -0.49
C57BLKS/J f 12.3 4.17   7 1.58 0.339 7.16, 18.0 -0.36
C57BR/cdJ f 33.6 8.9   8 3.15 0.265 18.2, 49.5 1.06
C57BR/cdJ m 32.7 9.68   8 3.42 0.296 19.5, 43.5 0.58
C57L/J f 19.9 7.68   8 2.71 0.385 9.56, 33.7 0.15
C57L/J m 15.1 5.26   6 2.15 0.349 8.62, 24.2 -0.27
CBA/J f 12.3 14.7   8 5.2 1.2 1.49, 42.5 -0.36
CBA/J m 2.62 2.45   6 0.999 0.933 0.78, 7.42 -0.87
DBA/2J f 9.63 5.5   7 2.08 0.571 2.6, 20.1 -0.54
DBA/2J m 3.47 1.97   8 0.695 0.567 0.63, 6.05 -0.83
FVB/NJ f 8.3 11.5   8 4.08 1.39 1.11, 36.5 -0.63
KK/HlJ f 28.0 13.7   7 5.19 0.49 7.93, 42.9 0.69
KK/HlJ m 19.0 9.62   7 3.63 0.507 11.2, 37.4 -0.08
LP/J f 15.5 17.6   7 6.67 1.14 4.76, 52.6 -0.15
LP/J m 18.6 8.15   8 2.88 0.437 8.05, 28.0 -0.1
MOLF/EiJ f 83.7 7.35   9 2.45 0.0878 69.8, 92.4 4.39
MOLF/EiJ m 81.7 6.18   7 2.34 0.0757 75.5, 90.0 2.94
MRL/MpJ f 14.8 10.6   6 4.31 0.715 2.17, 26.7 -0.19
MRL/MpJ m 31.0 23.2   8 8.19 0.746 2.76, 56.0 0.49
NOD.B10Sn-H2b/J f 24.2 15.2   7 5.75 0.628 13.0, 57.0 0.43
NOD.B10Sn-H2b/J m 11.1 4.82   6 1.97 0.435 6.88, 18.6 -0.47
NON/ShiLtJ f 11.7 3.58   7 1.35 0.306 6.32, 17.8 -0.4
NON/ShiLtJ m 31.6 21.6   7 8.18 0.686 13.7, 77.6 0.52
NZO/HlLtJ f 23.6 24.7   3 14.3 1.05 8.87, 52.1 0.39
NZW/LacJ f 20.3 23.2   8 8.2 1.14 4.39, 73.1 0.17
NZW/LacJ m 9.93 5.59   7 2.11 0.563 4.05, 20.5 -0.52
P/J f 20.3 18.2   5 8.16 0.901 4.86, 48.7 0.17
P/J m 30.9 10.0   4 5.01 0.324 18.6, 42.8 0.49
PL/J f 16.9 4.67   4 2.34 0.276 11.9, 22.8 -0.05
PL/J m 70.0 4.72   5 2.11 0.0674 64.1, 76.8 2.38
PWD/PhJ f 15.9 26.8   8 9.49 1.69 1.78, 80.4 -0.12
PWD/PhJ m 3.49 1.18   8 0.416 0.338 1.96, 5.16 -0.83
RIIIS/J m 3.34 1.5   8 0.529 0.448 1.18, 5.55 -0.84
SJL/J f 17.0 8.16   8 2.89 0.48 7.8, 29.0 -0.05
SJL/J m 36.8 26.4   7 9.99 0.719 7.19, 78.2 0.77
SM/J f 3.1 3.76   7 1.42 1.21 0.3, 11.2 -0.97
SWR/J f 33.1 42.2   7 16.0 1.28 5.46, 95.7 1.03
SWR/J m 10.0 6.42   6 2.62 0.64 4.46, 22.3 -0.52
WSB/EiJ f 12.1 25.1   8 8.88 2.07 1.64, 74.1 -0.37
WSB/EiJ m 4.38 1.29   7 0.489 0.295 2.61, 5.87 -0.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 12.8686 5.0619 22.8331 2.904
129S1/SvImJ m 17.2375 4.735 26.5585 7.9165
BALB/cByJ f 17.5 4.735 26.821 8.179
BALB/cByJ m 47.2 5.4675 57.9629 36.4371
BTBR T+ Itpr3tf/J f 3.875 4.735 13.196 0.0
BTBR T+ Itpr3tf/J m 4.75 5.9893 16.5402 0.0
BUB/BnJ f 2.7425 4.735 12.0635 0.0
BUB/BnJ m 10.835 5.4675 21.5979 0.0721
C3H/HeJ f 4.2 4.735 13.521 0.0
C3H/HeJ m 5.7387 4.735 15.0597 0.0
C57BL/6J f 8.475 4.735 17.796 0.0
C57BL/6J m 10.4586 5.0619 20.4231 0.494
C57BR/cdJ f 33.625 4.735 42.946 24.304
C57BR/cdJ m 32.7125 4.735 42.0335 23.3915
C57L/J f 19.945 4.735 29.266 10.624
C57L/J m 15.0867 5.4675 25.8496 4.3237
CBA/J f 12.2788 4.735 21.5997 2.9578
CBA/J m 2.6217 5.4675 13.3846 0.0
DBA/2J f 9.6329 5.0619 19.5974 0.0
DBA/2J m 3.4662 4.735 12.7872 0.0
KK/HlJ f 28.0043 5.0619 37.9688 18.0397
KK/HlJ m 18.9571 5.0619 28.9217 8.9926
LP/J f 15.4971 5.0619 25.4617 5.5326
LP/J m 18.6312 4.735 27.9522 9.3103
MOLF/EiJ f 83.6778 4.4642 92.4657 74.8899
MOLF/EiJ m 81.6571 5.0619 91.6217 71.6926
MRL/MpJ f 14.7583 5.4675 25.5213 3.9954
MRL/MpJ m 31.0325 4.735 40.3535 21.7115
NOD.B10Sn-H2b/J f 24.2143 5.0619 34.1788 14.2497
NOD.B10Sn-H2b/J m 11.075 5.4675 21.8379 0.3121
NON/ShiLtJ f 11.6957 5.0619 21.6603 1.7312
NON/ShiLtJ m 31.5714 5.0619 41.536 21.6069
NZW/LacJ f 20.2637 4.735 29.5847 10.9428
NZW/LacJ m 9.9314 5.0619 19.896 0.0
P/J f 20.256 5.9893 32.0462 8.4658
P/J m 30.925 6.6963 44.1068 17.7432
PL/J f 16.95 6.6963 30.1318 3.7682
PL/J m 69.96 5.9893 81.7502 58.1698
PWD/PhJ f 15.8663 4.735 25.1872 6.5453
PWD/PhJ m 3.485 4.735 12.806 0.0
SJL/J f 16.995 4.735 26.316 7.674
SJL/J m 36.77 5.0619 46.7345 26.8055
SWR/J f 33.06 5.0619 43.0245 23.0955
SWR/J m 10.0367 5.4675 20.7996 0.0
WSB/EiJ f 12.1225 4.735 21.4435 2.8015
WSB/EiJ m 4.3786 5.0619 14.3431 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 15.053 3.4657 21.8753 8.2308
BALB/cByJ both 32.35 3.6164 39.469 25.231
BTBR T+ Itpr3tf/J both 4.3125 3.8175 11.8273 0.0
BUB/BnJ both 6.7887 3.6164 13.9078 0.0
C3H/HeJ both 4.9694 3.3481 11.5603 0.0
C57BL/6J both 9.4668 3.4657 16.289 2.6445
C57BR/cdJ both 33.1688 3.3481 39.7597 26.5778
C57L/J both 17.5158 3.6164 24.6348 10.3968
CBA/J both 7.4502 3.6164 14.5692 0.3312
DBA/2J both 6.5496 3.4657 13.3718 0.0
KK/HlJ both 23.4807 3.5793 30.5267 16.4347
LP/J both 17.0642 3.4657 23.8864 10.2419
MOLF/EiJ both 82.6675 3.3746 89.3105 76.0244
MRL/MpJ both 22.8954 3.6164 30.0144 15.7764
NOD.B10Sn-H2b/J both 17.6446 3.7255 24.9783 10.3109
NON/ShiLtJ both 21.6336 3.5793 28.6796 14.5876
NZW/LacJ both 15.0976 3.4657 21.9198 8.2753
P/J both 25.5905 4.492 34.4331 16.7479
PL/J both 43.455 4.492 52.2976 34.6124
PWD/PhJ both 9.6756 3.3481 16.2665 3.0847
SJL/J both 26.8825 3.4657 33.7048 20.0602
SWR/J both 21.5483 3.7255 28.882 14.2146
WSB/EiJ both 8.2505 3.4657 15.0728 1.4283




  GWAS USING LINEAR MIXED MODELS