Project measure / variable:   Petkova1   CD8_effector_M12

ID, description, units MPD:24272   CD8_effector_M12   CD8 T cells, effector, as percentage of total CD8 T cells   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, effector, as percentage of total CD8 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means12.7   % 14.5   %
Median of the strain means7.91   % 9.00   %
SD of the strain means± 13.0 ± 19.1
Coefficient of variation (CV)1.03 1.31
Min–max range of strain means0.665   –   65.6   % 2.16   –   83.1   %
Mean sample size per strain7.6   mice 7.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 651.3553 651.3553 11.4017 0.0008
strain 28 92451.448 3301.8374 57.7973 < 0.0001
sex:strain 28 31734.5545 1133.3769 19.8393 < 0.0001
Residuals 390 22279.8925 57.1279


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.11 3.13   8 1.11 0.44 3.98, 12.7 -0.43
129S1/SvImJ m 83.1 5.94   8 2.1 0.0714 75.0, 90.3 3.59
A/J f 7.73 3.23   8 1.14 0.418 3.29, 13.6 -0.38
A/J m 4.42 1.09   8 0.384 0.246 2.98, 5.71 -0.53
AKR/J m 16.3 28.5   5 12.7 1.75 2.05, 67.2 0.09
BALB/cByJ f 13.0 5.71   8 2.02 0.44 5.48, 20.0 0.02
BALB/cByJ m 31.4 21.1   8 7.45 0.672 14.4, 68.0 0.88
BTBR T+ Itpr3tf/J f 4.02 0.931   8 0.329 0.231 2.79, 6.03 -0.67
BTBR T+ Itpr3tf/J m 4.28 1.67   7 0.633 0.391 2.25, 6.78 -0.54
BUB/BnJ f 5.27 3.51   6 1.43 0.667 1.62, 11.6 -0.57
BUB/BnJ m 8.92 6.05   9 2.02 0.678 2.54, 20.6 -0.29
C3H/HeJ f 18.9 10.3   8 3.62 0.543 10.5, 41.5 0.48
C3H/HeJ m 10.9 3.51   8 1.24 0.321 6.52, 17.5 -0.19
C57BL/10J f 22.1 19.7   8 6.95 0.889 6.62, 68.5 0.72
C57BL/10J m 2.92 1.2   7 0.455 0.412 1.59, 4.98 -0.61
C57BL/6J f 29.1 10.9   8 3.84 0.373 10.3, 44.0 1.26
C57BL/6J m 13.7 5.11   8 1.81 0.372 8.18, 22.7 -0.04
C57BLKS/J f 5.02 0.954   8 0.337 0.19 3.64, 6.35 -0.59
C57BLKS/J m 2.34 0.925   8 0.327 0.395 1.46, 3.77 -0.64
C57BR/cdJ f 26.4 14.4   8 5.1 0.546 13.3, 55.3 1.05
C57BR/cdJ m 23.0 8.01   8 2.83 0.348 13.2, 37.6 0.44
C57L/J f 12.6 2.8   7 1.06 0.222 7.68, 16.8 -0.01
C57L/J m 21.2 10.6   8 3.74 0.5 9.34, 42.8 0.35
CAST/EiJ f 12.2 3.23   3 1.87 0.265 9.04, 15.5 -0.04
CBA/J f 10.4 22.4   8 7.91 2.14 1.4, 65.7 -0.18
CBA/J m 2.16 0.757   8 0.268 0.351 1.37, 3.57 -0.65
DBA/2J f 6.71 2.63   6 1.08 0.393 4.32, 11.3 -0.46
DBA/2J m 3.64 1.25   7 0.471 0.342 2.2, 6.12 -0.57
FVB/NJ f 3.12 0.676   8 0.239 0.217 2.1, 4.06 -0.73
FVB/NJ m 4.44 1.01   8 0.359 0.229 3.04, 5.66 -0.53
KK/HlJ f 10.8 3.1   8 1.09 0.286 7.04, 17.5 -0.15
KK/HlJ m 13.3 5.67   8 2.0 0.425 8.01, 26.0 -0.06
LP/J f 8.13 7.62   7 2.88 0.937 3.52, 24.9 -0.35
LP/J m 10.8 5.87   8 2.08 0.546 6.61, 25.0 -0.2
MOLF/EiJ f 65.6 4.98   7 1.88 0.0759 57.9, 73.4 4.06
MOLF/EiJ m 76.9 13.1   9 4.35 0.17 57.3, 90.4 3.26
MRL/MpJ f 29.3 8.59   8 3.04 0.293 20.9, 43.1 1.27
MRL/MpJ m 3.48 3.78   8 1.34 1.08 0.67, 12.3 -0.58
NON/ShiLtJ f 6.15 4.22   8 1.49 0.686 1.55, 14.0 -0.5
NON/ShiLtJ m 4.34 2.22   7 0.839 0.511 2.39, 8.62 -0.53
NZO/HlLtJ f 27.1 3.6   7 1.36 0.133 21.4, 31.9 1.1
NZO/HlLtJ m 14.6 10.6   7 4.01 0.726 4.36, 30.2 0.0
NZW/LacJ f 3.46 0.85   8 0.3 0.246 1.57, 4.08 -0.71
NZW/LacJ m 7.28 1.79   8 0.632 0.246 5.02, 10.7 -0.38
P/J f 2.74 1.08   8 0.381 0.394 1.24, 4.81 -0.76
P/J m 11.8 4.06   7 1.53 0.343 6.74, 20.1 -0.14
PL/J f 8.08 7.31   7 2.76 0.905 3.99, 24.5 -0.35
PL/J m 9.45 2.66   6 1.09 0.282 6.01, 13.9 -0.27
PWD/PhJ f 3.77 3.75   8 1.33 0.994 1.11, 10.4 -0.69
PWD/PhJ m 9.07 4.28   8 1.51 0.472 3.35, 17.1 -0.29
RIIIS/J f 3.42 1.17   8 0.413 0.341 1.93, 4.83 -0.71
RIIIS/J m 5.16 2.09   8 0.739 0.406 2.48, 9.45 -0.49
SJL/J f 16.4 10.9   8 3.85 0.665 6.53, 35.2 0.28
SJL/J m 19.1 13.2   9 4.39 0.69 6.78, 44.4 0.24
SM/J f 0.665 0.309   8 0.109 0.464 0.35, 1.21 -0.92
SM/J m 4.63 6.41   8 2.26 1.38 0.44, 17.5 -0.52
SWR/J f 5.94 1.5   7 0.566 0.252 4.32, 8.66 -0.52
SWR/J m 7.36 2.13   7 0.804 0.289 3.66, 10.2 -0.38
WSB/EiJ f 5.9 2.8   8 0.992 0.475 2.48, 11.3 -0.52
WSB/EiJ m 6.13 2.47   8 0.872 0.402 4.19, 11.9 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.1062 2.6723 12.3601 1.8524
129S1/SvImJ m 83.075 2.6723 88.3288 77.8212
A/J f 7.7275 2.6723 12.9813 2.4737
A/J m 4.415 2.6723 9.6688 0.0
BALB/cByJ f 12.9588 2.6723 18.2126 7.7049
BALB/cByJ m 31.3625 2.6723 36.6163 26.1087
BTBR T+ Itpr3tf/J f 4.0237 2.6723 9.2776 0.0
BTBR T+ Itpr3tf/J m 4.2771 2.8568 9.8937 0.0
BUB/BnJ f 5.2667 3.0857 11.3333 0.0
BUB/BnJ m 8.9222 2.5194 13.8756 3.9689
C3H/HeJ f 18.8625 2.6723 24.1163 13.6087
C3H/HeJ m 10.9237 2.6723 16.1776 5.6699
C57BL/10J f 22.1113 2.6723 27.3651 16.8574
C57BL/10J m 2.9229 2.8568 8.5395 0.0
C57BL/6J f 29.1 2.6723 34.3538 23.8462
C57BL/6J m 13.745 2.6723 18.9988 8.4912
C57BLKS/J f 5.02 2.6723 10.2738 0.0
C57BLKS/J m 2.3438 2.6723 7.5976 0.0
C57BR/cdJ f 26.4375 2.6723 31.6913 21.1837
C57BR/cdJ m 23.025 2.6723 28.2788 17.7712
C57L/J f 12.6257 2.8568 18.2423 7.0091
C57L/J m 21.18 2.6723 26.4338 15.9262
CBA/J f 10.4325 2.6723 15.6863 5.1787
CBA/J m 2.1575 2.6723 7.4113 0.0
DBA/2J f 6.7117 3.0857 12.7783 0.645
DBA/2J m 3.6429 2.8568 9.2595 0.0
FVB/NJ f 3.1212 2.6723 8.3751 0.0
FVB/NJ m 4.4362 2.6723 9.6901 0.0
KK/HlJ f 10.8425 2.6723 16.0963 5.5887
KK/HlJ m 13.335 2.6723 18.5888 8.0812
LP/J f 8.1271 2.8568 13.7437 2.5105
LP/J m 10.7637 2.6723 16.0176 5.5099
MOLF/EiJ f 65.6429 2.8568 71.2595 60.0263
MOLF/EiJ m 76.9 2.5194 81.8534 71.9466
MRL/MpJ f 29.275 2.6723 34.5288 24.0212
MRL/MpJ m 3.4837 2.6723 8.7376 0.0
NON/ShiLtJ f 6.1525 2.6723 11.4063 0.8987
NON/ShiLtJ m 4.34 2.8568 9.9566 0.0
NZO/HlLtJ f 27.0714 2.8568 32.688 21.4548
NZO/HlLtJ m 14.6143 2.8568 20.2309 8.9977
NZW/LacJ f 3.455 2.6723 8.7088 0.0
NZW/LacJ m 7.2788 2.6723 12.5326 2.0249
P/J f 2.74 2.6723 7.9938 0.0
P/J m 11.8286 2.8568 17.4452 6.212
PL/J f 8.0757 2.8568 13.6923 2.4591
PL/J m 9.4467 3.0857 15.5133 3.38
PWD/PhJ f 3.7725 2.6723 9.0263 0.0
PWD/PhJ m 9.0675 2.6723 14.3213 3.8137
RIIIS/J f 3.4237 2.6723 8.6776 0.0
RIIIS/J m 5.1562 2.6723 10.4101 0.0
SJL/J f 16.3663 2.6723 21.6201 11.1124
SJL/J m 19.0733 2.5194 24.0267 14.12
SM/J f 0.665 2.6723 5.9188 0.0
SM/J m 4.6263 2.6723 9.8801 0.0
SWR/J f 5.9357 2.8568 11.5523 0.3191
SWR/J m 7.3586 2.8568 12.9752 1.742
WSB/EiJ f 5.8987 2.6723 11.1526 0.6449
WSB/EiJ m 6.1275 2.6723 11.3813 0.8737


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 45.0906 1.8896 48.8057 41.3756
A/J both 6.0712 1.8896 9.7863 2.3562
BALB/cByJ both 22.1606 1.8896 25.8757 18.4456
BTBR T+ Itpr3tf/J both 4.1504 1.9559 7.9959 0.305
BUB/BnJ both 7.0944 1.9918 11.0104 3.1785
C3H/HeJ both 14.8931 1.8896 18.6082 11.1781
C57BL/10J both 12.5171 1.9559 16.3625 8.6716
C57BL/6J both 21.4225 1.8896 25.1375 17.7075
C57BLKS/J both 3.6819 1.8896 7.3969 0.0
C57BR/cdJ both 24.7313 1.8896 28.4463 21.0162
C57L/J both 16.9029 1.9559 20.7483 13.0574
CBA/J both 6.295 1.8896 10.01 2.58
DBA/2J both 5.1773 2.1025 9.311 1.0436
FVB/NJ both 3.7787 1.8896 7.4938 0.0637
KK/HlJ both 12.0888 1.8896 15.8038 8.3737
LP/J both 9.4454 1.9559 13.2909 5.6
MOLF/EiJ both 71.2714 1.9045 75.0158 67.527
MRL/MpJ both 16.3794 1.8896 20.0944 12.6643
NON/ShiLtJ both 5.2463 1.9559 9.0917 1.4008
NZO/HlLtJ both 20.8429 2.02 24.8144 16.8713
NZW/LacJ both 5.3669 1.8896 9.0819 1.6518
P/J both 7.2843 1.9559 11.1297 3.4389
PL/J both 8.7612 2.1025 12.8949 4.6275
PWD/PhJ both 6.42 1.8896 10.135 2.705
RIIIS/J both 4.29 1.8896 8.005 0.575
SJL/J both 17.7198 1.8363 21.3302 14.1094
SM/J both 2.6456 1.8896 6.3607 0.0
SWR/J both 6.6471 2.02 10.6187 2.6756
WSB/EiJ both 6.0131 1.8896 9.7282 2.2981




  GWAS USING LINEAR MIXED MODELS