Project measure / variable:   Petkova1   CD8_effector_M06

ID, description, units MPD:24271   CD8_effector_M06   CD8 T cells, effector, as percentage of total CD8 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, effector, as percentage of total CD8 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means40.8   % 37.9   %
Median of the strain means39.0   % 33.4   %
SD of the strain means± 22.3 ± 23.4
Coefficient of variation (CV)0.548 0.617
Min–max range of strain means7.43   –   87.2   % 6.52   –   84.5   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 98.1707 98.1707 1.1227 0.2899
strain 30 207204.3507 6906.8117 78.9907 < 0.0001
sex:strain 30 42626.0186 1420.8673 16.2499 < 0.0001
Residuals 435 38035.6639 87.4383


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 71.2 8.57   8 3.03 0.121 64.1, 87.1 1.36
129S1/SvImJ m 75.6 3.24   8 1.14 0.0428 71.3, 79.5 1.61
A/J f 36.5 8.86   8 3.13 0.243 23.5, 46.0 -0.19
A/J m 33.4 5.84   8 2.06 0.175 27.9, 46.6 -0.19
AKR/J f 15.9 6.66   8 2.36 0.419 9.1, 28.2 -1.11
AKR/J m 24.2 4.06   8 1.43 0.167 19.5, 30.8 -0.59
BALB/cByJ f 58.5 6.07   8 2.15 0.104 48.8, 68.5 0.79
BALB/cByJ m 31.3 37.1   8 13.1 1.18 3.48, 90.6 -0.28
BTBR T+ Itpr3tf/J f 28.0 4.12   8 1.46 0.147 19.7, 33.3 -0.57
BTBR T+ Itpr3tf/J m 26.5 7.87   8 2.78 0.297 15.2, 34.2 -0.49
BUB/BnJ f 42.7 8.63   8 3.05 0.202 28.3, 52.4 0.09
BUB/BnJ m 40.5 8.93   8 3.16 0.22 22.1, 53.2 0.11
C3H/HeJ f 28.6 5.52   8 1.95 0.193 20.2, 36.5 -0.55
C3H/HeJ m 19.6 3.92   8 1.39 0.2 14.4, 26.2 -0.78
C57BL/10J f 24.8 5.96   8 2.11 0.24 12.8, 31.1 -0.72
C57BL/10J m 19.2 4.08   8 1.44 0.213 12.8, 26.1 -0.8
C57BL/6J f 15.3 5.8   8 2.05 0.379 9.36, 24.9 -1.14
C57BL/6J m 17.5 4.7   8 1.66 0.269 10.3, 22.6 -0.87
C57BLKS/J f 7.43 2.69   8 0.951 0.362 3.98, 12.9 -1.49
C57BLKS/J m 10.2 1.95   8 0.688 0.191 7.68, 13.4 -1.18
C57BR/cdJ f 69.1 2.54   8 0.897 0.0367 66.1, 74.2 1.27
C57BR/cdJ m 52.4 3.85   8 1.36 0.0735 44.4, 57.7 0.62
C57L/J f 41.6 4.67   8 1.65 0.112 37.0, 51.8 0.04
C57L/J m 39.8 11.2   8 3.97 0.282 21.2, 58.1 0.08
CAST/EiJ f 63.8 28.8   6 11.8 0.451 34.7, 91.8 1.03
CBA/J f 25.9 9.44   8 3.34 0.364 18.0, 47.3 -0.67
CBA/J m 35.8 5.19   8 1.84 0.145 28.4, 46.3 -0.09
DBA/2J f 26.5 6.94   8 2.45 0.262 19.6, 38.2 -0.64
DBA/2J m 37.4 8.93   8 3.16 0.239 26.1, 49.8 -0.02
FVB/NJ f 20.7 4.7   8 1.66 0.227 14.4, 27.7 -0.9
FVB/NJ m 18.6 4.67   8 1.65 0.251 14.9, 29.1 -0.82
KK/HlJ f 54.3 12.6   8 4.45 0.232 39.2, 74.6 0.6
KK/HlJ m 57.5 8.99   8 3.18 0.156 40.1, 68.8 0.84
LP/J f 54.4 21.5   8 7.59 0.395 23.9, 78.3 0.61
LP/J m 40.1 25.1   8 8.88 0.627 15.6, 69.5 0.09
MOLF/EiJ f 78.2 4.01   7 1.52 0.0513 71.4, 82.8 1.67
MOLF/EiJ m 78.3 4.81   8 1.7 0.0614 68.6, 83.5 1.73
MRL/MpJ f 43.4 7.29   8 2.58 0.168 36.5, 58.0 0.12
MRL/MpJ m 43.3 6.69   8 2.37 0.154 32.3, 52.2 0.23
NOD.B10Sn-H2b/J f 20.9 8.36   9 2.79 0.399 7.69, 34.1 -0.89
NOD.B10Sn-H2b/J m 17.5 4.42   7 1.67 0.253 9.08, 24.2 -0.87
NON/ShiLtJ f 46.8 6.46   8 2.28 0.138 36.4, 59.4 0.27
NON/ShiLtJ m 80.4 2.23   8 0.787 0.0277 77.6, 83.3 1.82
NZO/HlLtJ f 17.8 6.09   8 2.15 0.342 13.3, 32.1 -1.03
NZO/HlLtJ m 24.7 7.14   8 2.52 0.289 17.2, 36.8 -0.56
NZW/LacJ f 66.1 9.1   8 3.22 0.138 50.8, 77.4 1.13
NZW/LacJ m 70.2 5.39   8 1.9 0.0767 61.9, 79.0 1.38
P/J f 56.7 11.9   8 4.21 0.21 32.9, 75.3 0.71
P/J m 6.52 1.91   8 0.675 0.293 4.69, 9.9 -1.34
PL/J f 11.9 4.51   7 1.7 0.38 7.41, 21.3 -1.29
PL/J m 12.1 3.96   7 1.5 0.327 5.53, 17.8 -1.1
PWD/PhJ f 87.2 5.82   8 2.06 0.0667 75.3, 93.2 2.08
PWD/PhJ m 84.5 4.53   8 1.6 0.0536 79.6, 90.6 1.99
RIIIS/J f 24.3 8.95   8 3.16 0.369 14.5, 42.1 -0.74
RIIIS/J m 66.8 5.45   8 1.93 0.0816 58.0, 73.3 1.24
SJL/J f 73.2 5.76   8 2.04 0.0787 63.6, 79.3 1.45
SJL/J m 10.6 8.5   6 3.47 0.804 4.13, 26.6 -1.17
SM/J f 17.6 10.1   16 2.53 0.575 5.23, 45.1 -1.04
SM/J m 9.86 3.83   8 1.35 0.388 5.38, 16.4 -1.2
SWR/J f 55.5 11.0   8 3.91 0.199 31.1, 65.5 0.66
SWR/J m 58.1 6.25   8 2.21 0.108 51.1, 66.4 0.86
WSB/EiJ f 20.7 8.4   8 2.97 0.405 10.7, 32.4 -0.9
WSB/EiJ m 31.9 17.0   6 6.96 0.535 16.9, 64.3 -0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 71.15 3.306 77.6478 64.6522
129S1/SvImJ m 75.6 3.306 82.0978 69.1022
A/J f 36.45 3.306 42.9478 29.9522
A/J m 33.45 3.306 39.9478 26.9522
AKR/J f 15.9 3.306 22.3978 9.4022
AKR/J m 24.2375 3.306 30.7353 17.7397
BALB/cByJ f 58.4625 3.306 64.9603 51.9647
BALB/cByJ m 31.3438 3.306 37.8415 24.846
BTBR T+ Itpr3tf/J f 28.0125 3.306 34.5103 21.5147
BTBR T+ Itpr3tf/J m 26.475 3.306 32.9728 19.9772
BUB/BnJ f 42.725 3.306 49.2228 36.2272
BUB/BnJ m 40.525 3.306 47.0228 34.0272
C3H/HeJ f 28.6375 3.306 35.1353 22.1397
C3H/HeJ m 19.5875 3.306 26.0853 13.0897
C57BL/10J f 24.7875 3.306 31.2853 18.2897
C57BL/10J m 19.175 3.306 25.6728 12.6772
C57BL/6J f 15.295 3.306 21.7928 8.7972
C57BL/6J m 17.4625 3.306 23.9603 10.9647
C57BLKS/J f 7.4262 3.306 13.924 0.9285
C57BLKS/J m 10.1762 3.306 16.674 3.6785
C57BR/cdJ f 69.075 3.306 75.5728 62.5772
C57BR/cdJ m 52.425 3.306 58.9228 45.9272
C57L/J f 41.625 3.306 48.1228 35.1272
C57L/J m 39.8375 3.306 46.3353 33.3397
CBA/J f 25.9125 3.306 32.4103 19.4147
CBA/J m 35.7875 3.306 42.2853 29.2897
DBA/2J f 26.475 3.306 32.9728 19.9772
DBA/2J m 37.375 3.306 43.8728 30.8772
FVB/NJ f 20.675 3.306 27.1728 14.1772
FVB/NJ m 18.6 3.306 25.0978 12.1022
KK/HlJ f 54.325 3.306 60.8228 47.8272
KK/HlJ m 57.475 3.306 63.9728 50.9772
LP/J f 54.3625 3.306 60.8603 47.8647
LP/J m 40.0875 3.306 46.5853 33.5897
MOLF/EiJ f 78.1857 3.5343 85.1321 71.2393
MOLF/EiJ m 78.2875 3.306 84.7853 71.7897
MRL/MpJ f 43.4375 3.306 49.9353 36.9397
MRL/MpJ m 43.3375 3.306 49.8353 36.8397
NOD.B10Sn-H2b/J f 20.9322 3.1169 27.0584 14.8061
NOD.B10Sn-H2b/J m 17.4829 3.5343 24.4293 10.5365
NON/ShiLtJ f 46.7875 3.306 53.2853 40.2897
NON/ShiLtJ m 80.375 3.306 86.8728 73.8772
NZO/HlLtJ f 17.8375 3.306 24.3353 11.3397
NZO/HlLtJ m 24.675 3.306 31.1728 18.1772
NZW/LacJ f 66.0875 3.306 72.5853 59.5897
NZW/LacJ m 70.2375 3.306 76.7353 63.7397
P/J f 56.7125 3.306 63.2103 50.2147
P/J m 6.5175 3.306 13.0153 0.0197
PL/J f 11.87 3.5343 18.8164 4.9236
PL/J m 12.1129 3.5343 19.0593 5.1665
PWD/PhJ f 87.25 3.306 93.7478 80.7522
PWD/PhJ m 84.5125 3.306 91.0103 78.0147
RIIIS/J f 24.275 3.306 30.7728 17.7772
RIIIS/J m 66.8 3.306 73.2978 60.3022
SJL/J f 73.25 3.306 79.7478 66.7522
SJL/J m 10.56 3.8175 18.063 3.057
SM/J f 17.6256 2.3377 22.2202 13.031
SM/J m 9.8563 3.306 16.354 3.3585
SWR/J f 55.4625 3.306 61.9603 48.9647
SWR/J m 58.1125 3.306 64.6103 51.6147
WSB/EiJ f 20.725 3.306 27.2228 14.2272
WSB/EiJ m 31.8833 3.8175 39.3863 24.3804


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 73.375 2.3377 77.9696 68.7804
A/J both 34.95 2.3377 39.5446 30.3554
AKR/J both 20.0688 2.3377 24.6634 15.4741
BALB/cByJ both 44.9031 2.3377 49.4977 40.3085
BTBR T+ Itpr3tf/J both 27.2438 2.3377 31.8384 22.6491
BUB/BnJ both 41.625 2.3377 46.2196 37.0304
C3H/HeJ both 24.1125 2.3377 28.7071 19.5179
C57BL/10J both 21.9813 2.3377 26.5759 17.3866
C57BL/6J both 16.3787 2.3377 20.9734 11.7841
C57BLKS/J both 8.8012 2.3377 13.3959 4.2066
C57BR/cdJ both 60.75 2.3377 65.3446 56.1554
C57L/J both 40.7313 2.3377 45.3259 36.1366
CBA/J both 30.85 2.3377 35.4446 26.2554
DBA/2J both 31.925 2.3377 36.5196 27.3304
FVB/NJ both 19.6375 2.3377 24.2321 15.0429
KK/HlJ both 55.9 2.3377 60.4946 51.3054
LP/J both 47.225 2.3377 51.8196 42.6304
MOLF/EiJ both 78.2366 2.4198 82.9925 73.4807
MRL/MpJ both 43.3875 2.3377 47.9821 38.7929
NOD.B10Sn-H2b/J both 19.2075 2.3562 23.8385 14.5766
NON/ShiLtJ both 63.5813 2.3377 68.1759 58.9866
NZO/HlLtJ both 21.2563 2.3377 25.8509 16.6616
NZW/LacJ both 68.1625 2.3377 72.7571 63.5679
P/J both 31.615 2.3377 36.2096 27.0204
PL/J both 11.9914 2.4991 16.9033 7.0796
PWD/PhJ both 85.8812 2.3377 90.4759 81.2866
RIIIS/J both 45.5375 2.3377 50.1321 40.9429
SJL/J both 41.905 2.525 46.8677 36.9423
SM/J both 13.7409 2.0245 17.72 9.7619
SWR/J both 56.7875 2.3377 61.3821 52.1929
WSB/EiJ both 26.3042 2.525 31.2669 21.3414




  GWAS USING LINEAR MIXED MODELS