Project measure / variable:   Petkova1   CD8_mem_effector_M24

ID, description, units MPD:24269   CD8_mem_effector_M24   CD8 T cells, effector memory, as percentage of total CD8 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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Petkova1 - CD8 T cells, effector memory, as percentage of total CD8 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means21.1   % 14.6   %
Median of the strain means14.2   % 10.3   %
SD of the strain means± 16.8 ± 8.40
Coefficient of variation (CV)0.798 0.575
Min–max range of strain means7.45   –   56.1   % 5.32   –   29.1   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2597.4941 2597.4941 32.2414 < 0.0001
strain 9 20936.463 2326.2737 28.8748 < 0.0001
sex:strain 9 4941.4113 549.0457 6.815 < 0.0001
Residuals 121 9748.2508 80.5641


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 14.2 11.4   6 4.66 0.806 4.71, 33.1 -0.41
129S1/SvImJ m 8.83 2.74   7 1.03 0.31 6.09, 14.5 -0.69
BALB/cByJ f 23.3 13.5   7 5.11 0.581 4.05, 40.7 0.13
C3H/HeJ m 21.9 11.8   8 4.16 0.537 7.05, 38.0 0.87
C57BL/10J f 56.1 19.4   8 6.85 0.345 24.2, 83.2 2.08
C57BL/10J m 29.1 9.59   6 3.91 0.329 19.3, 42.1 1.72
C57BL/6J f 51.3 12.1   8 4.29 0.237 27.1, 64.3 1.8
C57BL/6J m 22.3 13.4   8 4.75 0.604 8.84, 46.0 0.91
C57BLKS/J f 13.2 11.3   6 4.63 0.861 3.41, 32.5 -0.47
C57BLKS/J m 5.55 4.05   7 1.53 0.73 1.38, 13.6 -1.08
C57BR/cdJ f 11.9 9.08   7 3.43 0.762 5.58, 31.9 -0.55
C57BR/cdJ m 8.13 3.03   9 1.01 0.373 4.65, 14.8 -0.77
LP/J f 9.82 3.47   8 1.23 0.354 5.7, 14.7 -0.67
LP/J m 18.9 4.17   6 1.7 0.22 13.5, 24.4 0.51
NON/ShiLtJ f 18.0 8.95   8 3.16 0.497 8.88, 37.1 -0.18
NON/ShiLtJ m 22.4 8.11   7 3.06 0.361 12.2, 36.9 0.93
NZW/LacJ f 8.62 5.52   6 2.25 0.64 2.01, 16.7 -0.74
NZW/LacJ m 8.09 5.45   7 2.06 0.673 2.04, 17.2 -0.78
PWD/PhJ f 17.9 6.83   7 2.58 0.382 11.8, 29.6 -0.19
PWD/PhJ m 10.3 9.66   7 3.65 0.936 2.94, 30.3 -0.51
WSB/EiJ f 7.45 2.71   6 1.11 0.364 4.76, 11.2 -0.81
WSB/EiJ m 5.32 2.28   7 0.863 0.429 2.86, 9.5 -1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 14.1567 3.6643 21.4112 6.9022
129S1/SvImJ m 8.8314 3.3925 15.5478 2.1151
C57BL/10J f 56.0875 3.1734 62.3701 49.8049
C57BL/10J m 29.1167 3.6643 36.3712 21.8622
C57BL/6J f 51.2625 3.1734 57.5451 44.9799
C57BL/6J m 22.2537 3.1734 28.5363 15.9712
C57BLKS/J f 13.17 3.6643 20.4245 5.9155
C57BLKS/J m 5.55 3.3925 12.2664 0.0
C57BR/cdJ f 11.9229 3.3925 18.6392 5.2065
C57BR/cdJ m 8.1267 2.9919 14.05 2.2034
LP/J f 9.8187 3.1734 16.1013 3.5362
LP/J m 18.9167 3.6643 26.1712 11.6622
NON/ShiLtJ f 18.0225 3.1734 24.3051 11.7399
NON/ShiLtJ m 22.4286 3.3925 29.1449 15.7122
NZW/LacJ f 8.6183 3.6643 15.8728 1.3638
NZW/LacJ m 8.0929 3.3925 14.8092 1.3765
PWD/PhJ f 17.8857 3.3925 24.6021 11.1693
PWD/PhJ m 10.3214 3.3925 17.0378 3.6051
WSB/EiJ f 7.4467 3.6643 14.7012 0.1922
WSB/EiJ m 5.3229 3.3925 12.0392 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.494 2.4968 16.4372 6.5509
C57BL/10J both 42.6021 2.4237 47.4005 37.8037
C57BL/6J both 36.7581 2.2439 41.2006 32.3157
C57BLKS/J both 9.36 2.4968 14.3031 4.4169
C57BR/cdJ both 10.0248 2.2617 14.5023 5.5472
LP/J both 14.3677 2.4237 19.1661 9.5693
NON/ShiLtJ both 20.2255 2.3227 24.8239 15.6271
NZW/LacJ both 8.3556 2.4968 13.2987 3.4125
PWD/PhJ both 14.1036 2.3989 18.8528 9.3544
WSB/EiJ both 6.3848 2.4968 11.3279 1.4416




  GWAS USING LINEAR MIXED MODELS