Project measure / variable:   Petkova1   CD8_mem_effector_M18

ID, description, units MPD:24268   CD8_mem_effector_M18   CD8 T cells, effector memory, as percentage of total CD8 T cells   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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Petkova1 - CD8 T cells, effector memory, as percentage of total CD8 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means14.1   % 11.5   %
Median of the strain means9.62   % 9.23   %
SD of the strain means± 9.75 ± 9.36
Coefficient of variation (CV)0.692 0.814
Min–max range of strain means2.20   –   41.8   % 1.40   –   43.4   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1833.4973 1833.4973 33.224 < 0.0001
strain 22 17053.2055 775.1457 14.0461 < 0.0001
sex:strain 22 5945.0714 270.2305 4.8967 < 0.0001
Residuals 278 15341.6662 55.1858


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.6 1.53   7 0.577 0.273 3.92, 8.37 -0.87
129S1/SvImJ m 6.04 2.06   8 0.73 0.342 3.91, 9.54 -0.58
A/J f 15.8 6.06   8 2.14 0.384 7.65, 25.6 0.17
BALB/cByJ f 30.7 11.6   8 4.12 0.379 20.9, 55.9 1.7
BALB/cByJ m 13.8 3.87   6 1.58 0.28 8.69, 18.6 0.25
BTBR T+ Itpr3tf/J f 9.62 4.21   8 1.49 0.438 5.08, 16.8 -0.46
BTBR T+ Itpr3tf/J m 9.36 6.29   5 2.81 0.672 3.69, 19.6 -0.23
BUB/BnJ f 7.04 5.39   8 1.91 0.766 1.11, 15.2 -0.72
BUB/BnJ m 10.4 6.14   6 2.51 0.591 5.38, 20.8 -0.12
C3H/HeJ f 12.9 11.7   8 4.13 0.907 3.63, 40.9 -0.12
C3H/HeJ m 9.23 5.18   8 1.83 0.562 4.44, 20.4 -0.24
C57BL/10J f 26.6 15.9   7 6.0 0.597 10.7, 52.9 1.28
C57BL/10J m 43.4 0.0   1   0.0 0.0 43.4, 43.4 3.41
C57BL/6J f 21.4 6.15   8 2.17 0.287 14.9, 31.9 0.75
C57BL/6J m 20.8 9.28   7 3.51 0.446 10.0, 35.6 1.0
C57BLKS/J f 7.7 2.56   7 0.967 0.332 3.46, 10.6 -0.66
C57BR/cdJ f 8.49 4.03   8 1.42 0.475 4.3, 17.7 -0.58
C57BR/cdJ m 9.2 3.67   8 1.3 0.399 4.56, 14.8 -0.24
C57L/J f 22.7 15.5   8 5.48 0.683 7.56, 54.5 0.88
C57L/J m 5.3 1.43   6 0.585 0.27 3.74, 7.05 -0.66
CBA/J f 7.62 4.39   8 1.55 0.575 3.28, 16.3 -0.66
CBA/J m 2.94 1.82   6 0.742 0.617 1.8, 6.61 -0.91
DBA/2J f 29.8 11.4   7 4.32 0.384 9.98, 48.0 1.61
DBA/2J m 7.03 3.09   8 1.09 0.439 3.81, 12.1 -0.48
FVB/NJ f 8.93 4.94   8 1.74 0.553 4.36, 18.0 -0.53
KK/HlJ f 10.6 10.6   7 4.0 1.0 0.351, 25.3 -0.36
KK/HlJ m 7.91 3.01   7 1.14 0.381 4.62, 12.5 -0.38
LP/J f 5.12 3.51   7 1.33 0.685 1.64, 10.5 -0.92
LP/J m 14.8 7.77   8 2.75 0.526 6.75, 27.9 0.35
MOLF/EiJ f 16.3 7.35   9 2.45 0.452 7.59, 30.2 0.23
MOLF/EiJ m 18.2 6.09   7 2.3 0.334 9.92, 24.5 0.72
MRL/MpJ f 8.1 8.52   6 3.48 1.05 1.2, 20.3 -0.62
MRL/MpJ m 5.92 3.03   8 1.07 0.512 1.86, 10.8 -0.6
NOD.B10Sn-H2b/J f 41.8 17.9   7 6.76 0.428 15.2, 61.5 2.84
NOD.B10Sn-H2b/J m 20.2 8.01   6 3.27 0.397 9.01, 30.5 0.93
NON/ShiLtJ f 23.1 15.0   7 5.67 0.649 5.35, 49.4 0.92
NON/ShiLtJ m 9.72 4.44   7 1.68 0.457 4.9, 19.0 -0.19
NZO/HlLtJ f 15.2 7.02   3 4.05 0.462 11.0, 23.3 0.11
NZW/LacJ f 6.21 8.62   8 3.05 1.39 0.89, 26.5 -0.81
NZW/LacJ m 2.19 1.21   7 0.458 0.552 1.24, 4.87 -0.99
P/J f 18.2 11.4   5 5.11 0.627 6.99, 36.1 0.42
P/J m 29.4 6.82   4 3.41 0.232 20.0, 35.9 1.91
PL/J f 3.94 1.06   4 0.528 0.268 3.32, 5.51 -1.04
PL/J m 6.21 1.62   5 0.725 0.261 4.29, 8.18 -0.56
PWD/PhJ f 6.66 5.33   8 1.88 0.8 2.17, 17.1 -0.76
PWD/PhJ m 4.4 2.48   8 0.878 0.565 0.98, 9.57 -0.76
RIIIS/J m 12.5 6.62   8 2.34 0.529 6.15, 26.0 0.11
SJL/J f 23.6 9.79   8 3.46 0.415 9.47, 35.7 0.97
SJL/J m 12.2 8.42   7 3.18 0.69 3.09, 23.1 0.08
SM/J f 5.47 2.95   7 1.11 0.539 1.77, 9.33 -0.88
SWR/J f 7.54 5.7   7 2.15 0.756 -0.67
SWR/J m 4.68 0.776   6 0.317 0.166 3.46, 5.85 -0.73
WSB/EiJ f 2.2 1.73   8 0.611 0.786 1.07, 6.11 -1.22
WSB/EiJ m 1.4 0.323   7 0.122 0.231 0.85, 1.89 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.6 2.8078 11.1272 0.0728
129S1/SvImJ m 6.0375 2.6264 11.2078 0.8672
BALB/cByJ f 30.7375 2.6264 35.9078 25.5672
BALB/cByJ m 13.815 3.0328 19.7851 7.8449
BTBR T+ Itpr3tf/J f 9.6238 2.6264 14.794 4.4535
BTBR T+ Itpr3tf/J m 9.36 3.3222 15.8999 2.8201
BUB/BnJ f 7.0412 2.6264 12.2115 1.871
BUB/BnJ m 10.4017 3.0328 16.3718 4.4316
C3H/HeJ f 12.8637 2.6264 18.034 7.6935
C3H/HeJ m 9.2275 2.6264 14.3978 4.0572
C57BL/6J f 21.45 2.6264 26.6203 16.2797
C57BL/6J m 20.8143 2.8078 26.3415 15.2871
C57BR/cdJ f 8.4875 2.6264 13.6578 3.3172
C57BR/cdJ m 9.195 2.6264 14.3653 4.0247
C57L/J f 22.6662 2.6264 27.8365 17.496
C57L/J m 5.3033 3.0328 11.2734 0.0
CBA/J f 7.6225 2.6264 12.7928 2.4522
CBA/J m 2.945 3.0328 8.9151 0.0
DBA/2J f 29.8114 2.8078 35.3387 24.2842
DBA/2J m 7.0337 2.6264 12.204 1.8635
KK/HlJ f 10.563 2.8078 16.0902 5.0358
KK/HlJ m 7.9114 2.8078 13.4387 2.3842
LP/J f 5.1229 2.8078 10.6501 0.0
LP/J m 14.7862 2.6264 19.9565 9.616
MOLF/EiJ f 16.2567 2.4762 21.1312 11.3821
MOLF/EiJ m 18.2171 2.8078 23.7444 12.6899
MRL/MpJ f 8.0967 3.0328 14.0668 2.1266
MRL/MpJ m 5.9187 2.6264 11.089 0.7485
NOD.B10Sn-H2b/J f 41.8143 2.8078 47.3415 36.2871
NOD.B10Sn-H2b/J m 20.1683 3.0328 26.1384 14.1982
NON/ShiLtJ f 23.0929 2.8078 28.6201 17.5656
NON/ShiLtJ m 9.7186 2.8078 15.2458 4.1913
NZW/LacJ f 6.2087 2.6264 11.379 1.0385
NZW/LacJ m 2.1943 2.8078 7.7215 0.0
P/J f 18.198 3.3222 24.7379 11.6581
P/J m 29.4 3.7144 36.7118 22.0882
PL/J f 3.935 3.7144 11.2468 0.0
PL/J m 6.214 3.3222 12.7539 0.0
PWD/PhJ f 6.66 2.6264 11.8303 1.4897
PWD/PhJ m 4.3975 2.6264 9.5678 0.0
SJL/J f 23.5837 2.6264 28.754 18.4135
SJL/J m 12.21 2.8078 17.7372 6.6828
SWR/J f 7.5429 2.8078 13.0701 2.0156
SWR/J m 4.6833 3.0328 10.6534 0.0
WSB/EiJ f 2.1987 2.6264 7.369 0.0
WSB/EiJ m 1.3957 2.8078 6.9229 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.8187 1.9224 9.603 2.0345
BALB/cByJ both 22.2762 2.006 26.2251 18.3274
BTBR T+ Itpr3tf/J both 9.4919 2.1175 13.6603 5.3235
BUB/BnJ both 8.7215 2.006 12.6703 4.7726
C3H/HeJ both 11.0456 1.8572 14.7015 7.3897
C57BL/6J both 21.1321 1.9224 24.9164 17.3479
C57BR/cdJ both 8.8412 1.8572 12.4972 5.1853
C57L/J both 13.9848 2.006 17.9336 10.0359
CBA/J both 5.2837 2.006 9.2326 1.3349
DBA/2J both 18.4226 1.9224 22.2068 14.6384
KK/HlJ both 9.2372 1.9854 13.1456 5.3289
LP/J both 9.9546 1.9224 13.7388 6.1703
MOLF/EiJ both 17.2369 1.8719 20.9217 13.5521
MRL/MpJ both 7.0077 2.006 10.9566 3.0589
NOD.B10Sn-H2b/J both 30.9913 2.0665 35.0592 26.9234
NON/ShiLtJ both 16.4057 1.9854 20.3141 12.4974
NZW/LacJ both 4.2015 1.9224 7.9858 0.4173
P/J both 23.799 2.4917 28.7039 18.8941
PL/J both 5.0745 2.4917 9.9794 0.1696
PWD/PhJ both 5.5287 1.8572 9.1847 1.8728
SJL/J both 17.8969 1.9224 21.6811 14.1126
SWR/J both 6.1131 2.0665 10.181 2.0452
WSB/EiJ both 1.7972 1.9224 5.5815 0.0




  GWAS USING LINEAR MIXED MODELS