Project measure / variable:   Petkova1   CD8_mem_central_M24

ID, description, units MPD:24264   CD8_mem_central_M24   CD8 T cells, central memory, as percentage of total CD8 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, central memory, as percentage of total CD8 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means22.8   % 29.0   %
Median of the strain means21.6   % 31.7   %
SD of the strain means± 6.42 ± 15.6
Coefficient of variation (CV)0.281 0.536
Min–max range of strain means12.8   –   33.0   % 10.8   –   57.0   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 778.6587 778.6587 3.8564 0.0518
strain 9 12919.815 1435.535 7.1097 < 0.0001
sex:strain 9 5348.6149 594.2905 2.9433 0.0034
Residuals 121 24431.4012 201.9124


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.7 7.29   6 2.98 0.353 13.9, 33.4 -0.33
129S1/SvImJ m 10.8 3.56   7 1.35 0.331 4.89, 16.8 -1.17
BALB/cByJ f 15.5 13.8   7 5.21 0.891 -1.14
C3H/HeJ m 38.4 15.8   8 5.58 0.411 20.7, 72.9 0.6
C57BL/10J f 26.3 17.1   8 6.04 0.651 11.5, 58.2 0.54
C57BL/10J m 57.0 12.2   6 4.97 0.214 41.4, 71.0 1.8
C57BL/6J f 32.2 17.6   8 6.24 0.548 16.1, 67.6 1.46
C57BL/6J m 43.1 14.1   8 4.97 0.326 18.0, 60.2 0.9
C57BLKS/J f 33.0 6.79   6 2.77 0.205 26.5, 44.1 1.59
C57BLKS/J m 31.7 9.67   7 3.65 0.305 18.5, 47.4 0.17
C57BR/cdJ f 21.8 11.9   7 4.5 0.547 6.81, 43.3 -0.16
C57BR/cdJ m 43.2 27.7   9 9.22 0.64 13.6, 88.8 0.91
LP/J f 21.5 25.2   8 8.92 1.17 1.6, 82.6 -0.21
LP/J m 13.9 7.19   6 2.93 0.515 4.25, 25.5 -0.97
NON/ShiLtJ f 27.6 14.9   8 5.26 0.539 15.0, 58.2 0.74
NON/ShiLtJ m 34.2 15.4   7 5.83 0.451 10.6, 54.3 0.33
NZW/LacJ f 21.6 11.3   6 4.62 0.525 8.1, 35.8 -0.19
NZW/LacJ m 17.8 7.42   7 2.81 0.418 8.96, 30.6 -0.72
PWD/PhJ f 18.1 7.6   7 2.87 0.419 1.92, 24.5 -0.74
PWD/PhJ m 18.2 4.21   7 1.59 0.231 13.5, 26.2 -0.7
WSB/EiJ f 12.8 8.91   6 3.64 0.694 7.64, 30.2 -1.56
WSB/EiJ m 11.2 8.79   7 3.32 0.784 4.64, 29.8 -1.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.65 5.801 32.1347 9.1653
129S1/SvImJ m 10.7614 5.3707 21.3942 0.1287
C57BL/10J f 26.2625 5.0238 36.2085 16.3165
C57BL/10J m 56.9833 5.801 68.468 45.4986
C57BL/6J f 32.1875 5.0238 42.1335 22.2415
C57BL/6J m 43.0875 5.0238 53.0335 33.1415
C57BLKS/J f 33.0333 5.801 44.518 21.5486
C57BLKS/J m 31.6714 5.3707 42.3042 21.0387
C57BR/cdJ f 21.7586 5.3707 32.3913 11.1258
C57BR/cdJ m 43.2111 4.7365 52.5883 33.8339
LP/J f 21.525 5.0238 31.471 11.579
LP/J m 13.9483 5.801 25.433 2.4636
NON/ShiLtJ f 27.6 5.0238 37.546 17.654
NON/ShiLtJ m 34.1857 5.3707 44.8185 23.553
NZW/LacJ f 21.5833 5.801 33.068 10.0986
NZW/LacJ m 17.7529 5.3707 28.3856 7.1201
PWD/PhJ f 18.1314 5.3707 28.7642 7.4987
PWD/PhJ m 18.2286 5.3707 28.8613 7.5958
WSB/EiJ f 12.8317 5.801 24.3164 1.347
WSB/EiJ m 11.2243 5.3707 21.857 0.5915


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 15.7057 3.9527 23.5312 7.8802
C57BL/10J both 41.6229 3.837 49.2193 34.0265
C57BL/6J both 37.6375 3.5524 44.6704 30.6046
C57BLKS/J both 32.3524 3.9527 40.1779 24.5269
C57BR/cdJ both 32.4848 3.5805 39.5733 25.3963
LP/J both 17.7367 3.837 25.3331 10.1403
NON/ShiLtJ both 30.8929 3.6771 38.1726 23.6131
NZW/LacJ both 19.6681 3.9527 27.4936 11.8426
PWD/PhJ both 18.18 3.7977 25.6985 10.6615
WSB/EiJ both 12.028 3.9527 19.8535 4.2025




  GWAS USING LINEAR MIXED MODELS