Phenotype measure:   Petkova1   CD8_mem_central_M18

ID, description, units MPD:24263   CD8_mem_central_M18   CD8 T cells, central memory, as percentage of total CD8 T cells   [%]  at age 18mo
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, central memory, as percentage of total CD8 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means23.4   % 19.0   %
Median of the strain means24.3   % 18.8   %
SD of the strain means± 12.7 ± 12.2
Coefficient of variation (CV)0.544 0.643
Min–max range of strain means0.0147   –   50.8   % 0.0460   –   46.1   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 536.9723 536.9723 5.9788 0.0151
strain 22 44912.7725 2041.4897 22.7306 < 0.0001
sex:strain 22 5763.9949 261.9998 2.9172 < 0.0001
Residuals 278 24967.7967 89.8122


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.8 2.34   7 0.886 0.198 8.67, 15.5 -0.91
129S1/SvImJ m 12.5 3.96   8 1.4 0.317 7.29, 19.0 -0.53
A/J f 25.3 7.28   8 2.57 0.288 17.8, 38.8 0.15
BALB/cByJ f 31.6 6.73   8 2.38 0.213 23.5, 43.1 0.65
BALB/cByJ m 13.4 3.9   6 1.59 0.292 8.72, 19.4 -0.46
BTBR T+ Itpr3tf/J f 8.85 1.84   8 0.651 0.208 5.73, 11.2 -1.14
BTBR T+ Itpr3tf/J m 8.28 2.09   5 0.936 0.253 5.08, 10.9 -0.88
BUB/BnJ f 50.8 21.2   8 7.49 0.417 17.2, 79.6 2.16
BUB/BnJ m 29.4 15.8   6 6.46 0.539 6.09, 50.5 0.85
C3H/HeJ f 30.1 8.14   8 2.88 0.27 18.2, 43.3 0.53
C3H/HeJ m 24.4 15.4   8 5.44 0.63 13.9, 61.1 0.44
C57BL/10J f 38.7 15.0   7 5.69 0.388 16.9, 66.8 1.2
C57BL/10J m 34.5 0.0   1   0.0 0.0 34.5, 34.5 1.27
C57BL/6J f 41.2 13.4   8 4.73 0.324 26.7, 64.6 1.4
C57BL/6J m 30.5 9.89   7 3.74 0.324 13.3, 41.9 0.94
C57BLKS/J f 23.3 4.81   7 1.82 0.206 17.8, 31.0 -0.01
C57BR/cdJ f 21.9 7.61   8 2.69 0.347 12.4, 39.0 -0.12
C57BR/cdJ m 20.1 5.89   8 2.08 0.292 12.6, 32.7 0.09
C57L/J f 25.2 12.4   8 4.39 0.493 5.7, 43.9 0.14
C57L/J m 25.7 13.2   6 5.38 0.513 13.1, 48.8 0.55
CBA/J f 33.1 12.0   8 4.23 0.362 6.02, 46.4 0.76
CBA/J m 33.4 4.92   6 2.01 0.147 25.0, 39.4 1.18
DBA/2J f 32.2 7.72   7 2.92 0.24 25.6, 45.8 0.69
DBA/2J m 41.2 7.12   8 2.52 0.173 27.2, 51.5 1.81
FVB/NJ f 32.1 7.37   8 2.6 0.23 22.5, 45.5 0.68
KK/HlJ f 12.2 10.6   7 4.01 0.867 1.94, 29.2 -0.88
KK/HlJ m 21.2 14.4   7 5.44 0.677 6.82, 41.1 0.18
LP/J f 8.52 5.18   7 1.96 0.608 -1.17
LP/J m 14.0 8.76   8 3.1 0.628 5.88, 30.9 -0.41
MOLF/EiJ f 0.0147 0.0182   9 0.00606 1.24 -1.84
MOLF/EiJ m 0.046 0.112   7 0.0424 2.44 -1.55
MRL/MpJ f 24.3 12.1   6 4.95 0.498 2.39, 35.1 0.07
MRL/MpJ m 18.8 5.96   8 2.11 0.317 11.4, 29.5 -0.02
NOD.B10Sn-H2b/J f 17.7 8.23   7 3.11 0.466 6.79, 29.3 -0.45
NOD.B10Sn-H2b/J m 23.3 8.82   6 3.6 0.378 12.8, 34.7 0.35
NON/ShiLtJ f 21.9 9.08   7 3.43 0.415 6.81, 33.6 -0.12
NON/ShiLtJ m 11.3 6.34   7 2.4 0.561 0.41, 19.8 -0.63
NZO/HlLtJ f 24.7 20.1   3 11.6 0.815 4.23, 44.5 0.1
NZW/LacJ f 6.92 3.99   8 1.41 0.577 0.076, 13.9 -1.3
NZW/LacJ m 6.68 2.02   7 0.762 0.302 4.42, 10.3 -1.01
P/J f 26.5 13.3   5 5.97 0.503 10.5, 39.6 0.24
P/J m 23.5 5.67   4 2.83 0.241 17.4, 30.2 0.37
PL/J f 4.88 0.472   4 0.236 0.0966 4.21, 5.26 -1.46
PL/J m 1.55 0.767   5 0.343 0.494 0.55, 2.61 -1.43
PWD/PhJ f 34.2 19.8   8 6.99 0.577 0.52, 59.0 0.85
PWD/PhJ m 46.1 13.2   8 4.66 0.286 15.9, 59.8 2.21
RIIIS/J m 15.0 4.52   8 1.6 0.302 10.8, 22.0 -0.33
SJL/J f 20.2 8.03   8 2.84 0.398 9.64, 33.6 -0.25
SJL/J m 4.66 2.96   7 1.12 0.634 0.67, 9.96 -1.17
SM/J f 46.2 8.19   7 3.1 0.177 30.7, 53.4 1.79
SWR/J f 17.0 13.0   7 4.9 0.764 -0.5
SWR/J m 8.97 1.72   6 0.703 0.192 7.29, 10.9 -0.82
WSB/EiJ f 7.0 2.61   8 0.922 0.372 1.73, 10.0 -1.29
WSB/EiJ m 6.95 0.917   7 0.347 0.132 6.01, 8.69 -0.99


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.8229 3.5819 18.874 4.7717
129S1/SvImJ m 12.5125 3.3506 19.1083 5.9167
BALB/cByJ f 31.575 3.3506 38.1708 24.9792
BALB/cByJ m 13.3717 3.8689 20.9878 5.7555
BTBR T+ Itpr3tf/J f 8.8463 3.3506 15.442 2.2505
BTBR T+ Itpr3tf/J m 8.276 4.2382 16.6191 0.0
BUB/BnJ f 50.75 3.3506 57.3458 44.1542
BUB/BnJ m 29.3817 3.8689 36.9978 21.7655
C3H/HeJ f 30.1 3.3506 36.6958 23.5042
C3H/HeJ m 24.4375 3.3506 31.0333 17.8417
C57BL/6J f 41.225 3.3506 47.8208 34.6292
C57BL/6J m 30.4857 3.5819 37.5369 23.4345
C57BR/cdJ f 21.9125 3.3506 28.5083 15.3167
C57BR/cdJ m 20.1375 3.3506 26.7333 13.5417
C57L/J f 25.175 3.3506 31.7708 18.5792
C57L/J m 25.6833 3.8689 33.2995 18.0672
CBA/J f 33.0775 3.3506 39.6733 26.4817
CBA/J m 33.4333 3.8689 41.0495 25.8172
DBA/2J f 32.1571 3.5819 39.2083 25.106
DBA/2J m 41.15 3.3506 47.7458 34.5542
KK/HlJ f 12.2314 3.5819 19.2826 5.1803
KK/HlJ m 21.24 3.5819 28.2912 14.1888
LP/J f 8.5229 3.5819 15.574 1.4717
LP/J m 13.9525 3.3506 20.5483 7.3567
MOLF/EiJ f 0.0147 3.159 6.2332 0.0
MOLF/EiJ m 0.046 3.5819 7.0972 0.0
MRL/MpJ f 24.315 3.8689 31.9311 16.6989
MRL/MpJ m 18.8125 3.3506 25.4083 12.2167
NOD.B10Sn-H2b/J f 17.6557 3.5819 24.7069 10.6045
NOD.B10Sn-H2b/J m 23.3333 3.8689 30.9495 15.7172
NON/ShiLtJ f 21.8871 3.5819 28.9383 14.836
NON/ShiLtJ m 11.3 3.5819 18.3512 4.2488
NZW/LacJ f 6.9157 3.3506 13.5115 0.32
NZW/LacJ m 6.6757 3.5819 13.7269 0.0
P/J f 26.54 4.2382 34.8831 18.1969
P/J m 23.475 4.7385 32.8028 14.1472
PL/J f 4.885 4.7385 14.2128 0.0
PL/J m 1.552 4.2382 9.8951 0.0
PWD/PhJ f 34.24 3.3506 40.8358 27.6442
PWD/PhJ m 46.1125 3.3506 52.7083 39.5167
SJL/J f 20.1925 3.3506 26.7883 13.5967
SJL/J m 4.6643 3.5819 11.7155 0.0
SWR/J f 16.9814 3.5819 24.0326 9.9303
SWR/J m 8.9733 3.8689 16.5895 1.3572
WSB/EiJ f 7.0025 3.3506 13.5983 0.4067
WSB/EiJ m 6.9529 3.5819 14.004 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 12.1677 2.4524 16.9953 7.3401
BALB/cByJ both 22.4733 2.5591 27.5109 17.4357
BTBR T+ Itpr3tf/J both 8.5611 2.7013 13.8788 3.2434
BUB/BnJ both 40.0658 2.5591 45.1034 35.0282
C3H/HeJ both 27.2688 2.3692 31.9327 22.6048
C57BL/6J both 35.8554 2.4524 40.683 31.0277
C57BR/cdJ both 21.025 2.3692 25.6889 16.3611
C57L/J both 25.4292 2.5591 30.4668 20.3916
CBA/J both 33.2554 2.5591 38.293 28.2178
DBA/2J both 36.6536 2.4524 41.4812 31.826
KK/HlJ both 16.7357 2.5328 21.7216 11.7498
LP/J both 11.2377 2.4524 16.0653 6.4101
MOLF/EiJ both 0.0303 2.388 4.7311 0.0
MRL/MpJ both 21.5637 2.5591 26.6014 16.5261
NOD.B10Sn-H2b/J both 20.4945 2.6362 25.684 15.305
NON/ShiLtJ both 16.5936 2.5328 21.5795 11.6076
NZW/LacJ both 6.7957 2.4524 11.6233 1.9681
P/J both 25.0075 3.1787 31.2648 18.7502
PL/J both 3.2185 3.1787 9.4758 0.0
PWD/PhJ both 40.1763 2.3692 44.8402 35.5123
SJL/J both 12.4284 2.4524 17.256 7.6008
SWR/J both 12.9774 2.6362 18.1669 7.7879
WSB/EiJ both 6.9777 2.4524 11.8053 2.1501




  GWAS USING LINEAR MIXED MODELS