Phenotype measure:   Petkova1   CD8_mem_central_M12

ID, description, units MPD:24262   CD8_mem_central_M12   CD8 T cells, central memory, as percentage of total CD8 T cells   [%]  at age 12mo
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, central memory, as percentage of total CD8 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means20.5   % 21.3   %
Median of the strain means20.4   % 21.1   %
SD of the strain means± 11.5 ± 12.6
Coefficient of variation (CV)0.561 0.593
Min–max range of strain means0.0976   –   47.7   % 0.0539   –   53.0   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 50.9854 50.9854 1.0403 0.3084
strain 28 43887.6868 1567.4174 31.9819 < 0.0001
sex:strain 28 11844.156 423.0056 8.6311 < 0.0001
Residuals 389 19064.6749 49.0094


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.34 3.06   8 1.08 0.328 7.0, 14.9 -0.97
129S1/SvImJ m 4.58 2.05   8 0.726 0.449 2.13, 8.6 -1.32
A/J f 28.8 6.94   8 2.45 0.241 14.4, 35.5 0.73
A/J m 28.0 6.68   8 2.36 0.238 22.3, 43.4 0.54
AKR/J m 53.0 28.3   5 12.6 0.533 3.24, 72.3 2.52
BALB/cByJ f 47.7 8.56   8 3.03 0.18 37.6, 57.9 2.37
BALB/cByJ m 7.96 3.17   8 1.12 0.398 3.36, 12.5 -1.06
BTBR T+ Itpr3tf/J f 6.61 1.1   8 0.391 0.167 4.85, 8.74 -1.21
BTBR T+ Itpr3tf/J m 6.46 0.59   7 0.223 0.0913 5.5, 7.35 -1.17
BUB/BnJ f 45.4 10.4   6 4.23 0.228 36.0, 64.2 2.17
BUB/BnJ m 29.2 15.8   9 5.28 0.542 3.64, 45.9 0.63
C3H/HeJ f 10.6 3.66   8 1.3 0.345 5.34, 15.6 -0.86
C3H/HeJ m 19.3 7.95   8 2.81 0.412 12.8, 36.7 -0.16
C57BL/10J f 20.8 9.38   8 3.31 0.451 3.74, 36.0 0.03
C57BL/10J m 41.1 6.28   7 2.37 0.153 33.3, 50.1 1.57
C57BL/6J f 18.2 3.53   8 1.25 0.194 12.8, 22.6 -0.2
C57BL/6J m 30.2 6.43   8 2.27 0.213 16.5, 38.1 0.71
C57BLKS/J f 25.1 2.86   8 1.01 0.114 19.6, 28.2 0.4
C57BLKS/J m 20.3 2.74   8 0.969 0.135 16.3, 24.4 -0.08
C57BR/cdJ f 19.6 5.19   8 1.84 0.265 11.5, 25.3 -0.08
C57BR/cdJ m 25.3 7.55   8 2.67 0.298 14.7, 38.6 0.32
C57L/J f 16.6 6.64   7 2.51 0.401 10.4, 30.3 -0.34
C57L/J m 16.7 4.46   8 1.58 0.267 7.25, 20.8 -0.36
CAST/EiJ f 12.5 3.32   3 1.92 0.267 8.65, 14.8 -0.7
CBA/J f 30.6 13.8   8 4.88 0.451 0.8, 46.2 0.88
CBA/J m 35.3 5.5   8 1.94 0.156 26.6, 42.7 1.11
DBA/2J f 29.1 3.19   6 1.3 0.11 26.5, 35.3 0.75
DBA/2J m 32.3 6.82   7 2.58 0.211 21.6, 42.0 0.88
FVB/NJ f 25.1 4.8   8 1.7 0.191 18.1, 32.3 0.4
FVB/NJ m 30.7 6.42   8 2.27 0.209 20.5, 42.1 0.75
KK/HlJ f 21.3 8.9   8 3.15 0.418 12.6, 37.3 0.07
KK/HlJ m 21.9 8.98   8 3.18 0.41 13.0, 40.5 0.05
LP/J f 20.0 13.1   7 4.96 0.657 6.65, 37.6 -0.04
LP/J m 16.3 9.45   8 3.34 0.581 8.2, 33.0 -0.39
MOLF/EiJ f 0.0976 0.0315   7 0.0119 0.323 0.064, 0.15 -1.78
MOLF/EiJ m 0.0539 0.0755   9 0.0252 1.4 -1.68
MRL/MpJ f 26.8 8.32   8 2.94 0.311 15.2, 37.4 0.55
MRL/MpJ m 27.7 11.4   8 4.03 0.411 3.58, 40.2 0.51
NON/ShiLtJ f 35.5 7.48   8 2.65 0.211 23.2, 48.4 1.31
NON/ShiLtJ m 34.4 7.41   6 3.03 0.215 28.0, 48.7 1.04
NZO/HlLtJ f 19.2 2.83   7 1.07 0.147 15.5, 24.0 -0.11
NZO/HlLtJ m 23.9 11.7   7 4.41 0.488 12.5, 42.4 0.21
NZW/LacJ f 7.76 1.6   8 0.566 0.207 5.58, 10.5 -1.11
NZW/LacJ m 13.4 3.11   8 1.1 0.233 7.57, 17.3 -0.62
P/J f 21.9 4.89   8 1.73 0.223 15.9, 30.5 0.12
P/J m 24.6 5.05   7 1.91 0.205 17.8, 32.2 0.27
PL/J f 7.95 2.67   7 1.01 0.336 4.88, 10.7 -1.09
PL/J m 9.44 1.59   6 0.649 0.168 7.47, 11.4 -0.94
PWD/PhJ f 15.3 6.42   8 2.27 0.42 7.19, 24.8 -0.45
PWD/PhJ m 13.4 4.32   8 1.53 0.321 7.81, 18.4 -0.62
RIIIS/J f 7.19 0.795   8 0.281 0.111 6.23, 8.7 -1.16
RIIIS/J m 9.2 1.7   8 0.6 0.184 7.26, 11.7 -0.96
SJL/J f 23.1 10.7   8 3.8 0.464 6.12, 36.5 0.23
SJL/J m 8.48 4.2   9 1.4 0.495 2.62, 15.3 -1.01
SM/J f 34.2 4.52   8 1.6 0.132 28.7, 41.0 1.2
SM/J m 37.1 11.5   8 4.07 0.31 22.3, 53.0 1.26
SWR/J f 23.6 13.9   7 5.25 0.589 11.2, 51.2 0.27
SWR/J m 13.5 5.7   7 2.16 0.422 5.26, 23.9 -0.62
WSB/EiJ f 4.39 1.4   8 0.493 0.318 3.21, 6.92 -1.4
WSB/EiJ m 3.9 0.812   8 0.287 0.208 2.27, 4.97 -1.38


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.3362 2.4751 14.2025 4.47
129S1/SvImJ m 4.575 2.4751 9.4413 0.0
A/J f 28.7875 2.4751 33.6538 23.9212
A/J m 28.0125 2.4751 32.8788 23.1462
BALB/cByJ f 47.7 2.4751 52.5663 42.8337
BALB/cByJ m 7.9562 2.4751 12.8225 3.09
BTBR T+ Itpr3tf/J f 6.605 2.4751 11.4713 1.7387
BTBR T+ Itpr3tf/J m 6.4571 2.646 11.6594 1.2549
BUB/BnJ f 45.45 2.858 51.0691 39.8309
BUB/BnJ m 29.1867 2.3336 33.7746 24.5987
C3H/HeJ f 10.6175 2.4751 15.4838 5.7512
C3H/HeJ m 19.3125 2.4751 24.1788 14.4462
C57BL/10J f 20.78 2.4751 25.6463 15.9137
C57BL/10J m 41.1286 2.646 46.3308 35.9263
C57BL/6J f 18.175 2.4751 23.0413 13.3087
C57BL/6J m 30.2 2.4751 35.0663 25.3337
C57BLKS/J f 25.075 2.4751 29.9413 20.2087
C57BLKS/J m 20.2875 2.4751 25.1538 15.4212
C57BR/cdJ f 19.575 2.4751 24.4413 14.7087
C57BR/cdJ m 25.35 2.4751 30.2163 20.4837
C57L/J f 16.5571 2.646 21.7594 11.3549
C57L/J m 16.7313 2.4751 21.5975 11.865
CBA/J f 30.65 2.4751 35.5163 25.7837
CBA/J m 35.275 2.4751 40.1413 30.4087
DBA/2J f 29.0667 2.858 34.6858 23.4476
DBA/2J m 32.3429 2.646 37.5451 27.1406
FVB/NJ f 25.0625 2.4751 29.9288 20.1962
FVB/NJ m 30.7125 2.4751 35.5788 25.8462
KK/HlJ f 21.2875 2.4751 26.1538 16.4212
KK/HlJ m 21.9375 2.4751 26.8038 17.0712
LP/J f 19.9771 2.646 25.1794 14.7749
LP/J m 16.2662 2.4751 21.1325 11.4
MOLF/EiJ f 0.0976 2.646 5.2998 0.0
MOLF/EiJ m 0.0539 2.3336 4.6419 0.0
MRL/MpJ f 26.7875 2.4751 31.6538 21.9212
MRL/MpJ m 27.7225 2.4751 32.5888 22.8562
NON/ShiLtJ f 35.4875 2.4751 40.3538 30.6212
NON/ShiLtJ m 34.4 2.858 40.0191 28.7809
NZO/HlLtJ f 19.2143 2.646 24.4165 14.012
NZO/HlLtJ m 23.9143 2.646 29.1165 18.712
NZW/LacJ f 7.7563 2.4751 12.6225 2.89
NZW/LacJ m 13.3588 2.4751 18.225 8.4925
P/J f 21.9125 2.4751 26.7788 17.0462
P/J m 24.6 2.646 29.8023 19.3977
PL/J f 7.95 2.646 13.1523 2.7477
PL/J m 9.4433 2.858 15.0624 3.8242
PWD/PhJ f 15.275 2.4751 20.1413 10.4087
PWD/PhJ m 13.4475 2.4751 18.3138 8.5812
RIIIS/J f 7.1912 2.4751 12.0575 2.325
RIIIS/J m 9.2025 2.4751 14.0688 4.3362
SJL/J f 23.1275 2.4751 27.9938 18.2612
SJL/J m 8.4789 2.3336 13.0669 3.8909
SM/J f 34.225 2.4751 39.0913 29.3587
SM/J m 37.1 2.4751 41.9663 32.2337
SWR/J f 23.5857 2.646 28.788 18.3835
SWR/J m 13.5229 2.646 18.7251 8.3206
WSB/EiJ f 4.3862 2.4751 9.2525 0.0
WSB/EiJ m 3.8962 2.4751 8.7625 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 6.9556 1.7502 10.3966 3.5147
A/J both 28.4 1.7502 31.841 24.959
BALB/cByJ both 27.8281 1.7502 31.2691 24.3872
BTBR T+ Itpr3tf/J both 6.5311 1.8116 10.0928 2.9693
BUB/BnJ both 37.3183 1.8448 40.9454 33.6912
C3H/HeJ both 14.965 1.7502 18.406 11.524
C57BL/10J both 30.9543 1.8116 34.516 27.3925
C57BL/6J both 24.1875 1.7502 27.6285 20.7465
C57BLKS/J both 22.6812 1.7502 26.1222 19.2403
C57BR/cdJ both 22.4625 1.7502 25.9035 19.0215
C57L/J both 16.6442 1.8116 20.2059 13.0825
CBA/J both 32.9625 1.7502 36.4035 29.5215
DBA/2J both 30.7048 1.9474 34.5335 26.876
FVB/NJ both 27.8875 1.7502 31.3285 24.4465
KK/HlJ both 21.6125 1.7502 25.0535 18.1715
LP/J both 18.1217 1.8116 21.6834 14.56
MOLF/EiJ both 0.0757 1.764 3.5439 0.0
MRL/MpJ both 27.255 1.7502 30.696 23.814
NON/ShiLtJ both 34.9438 1.8904 38.6604 31.2271
NZO/HlLtJ both 21.5643 1.871 25.2428 17.8857
NZW/LacJ both 10.5575 1.7502 13.9985 7.1165
P/J both 23.2563 1.8116 26.818 19.6945
PL/J both 8.6967 1.9474 12.5254 4.8679
PWD/PhJ both 14.3613 1.7502 17.8022 10.9203
RIIIS/J both 8.1969 1.7502 11.6378 4.7559
SJL/J both 15.8032 1.7009 19.1472 12.4592
SM/J both 35.6625 1.7502 39.1035 32.2215
SWR/J both 18.5543 1.871 22.2328 14.8757
WSB/EiJ both 4.1412 1.7502 7.5822 0.7003




  GWAS USING LINEAR MIXED MODELS