Phenotype measure:   Petkova1   CD8_mem_central_M06

ID, description, units MPD:24261   CD8_mem_central_M06   CD8 T cells, central memory, as percentage of total CD8 T cells   [%]  at age 6mo
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, central memory, as percentage of total CD8 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means10.6   % 12.0   %
Median of the strain means8.80   % 10.0   %
SD of the strain means± 8.48 ± 9.17
Coefficient of variation (CV)0.799 0.767
Min–max range of strain means0.00471   –   40.4   % 0.0107   –   33.3   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 122.3165 122.3165 9.7384 0.0019
strain 30 34020.3457 1134.0115 90.2861 < 0.0001
sex:strain 30 3557.505 118.5835 9.4412 < 0.0001
Residuals 435 5463.6893 12.5602


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.96 2.09   8 0.738 0.421 1.81, 7.46 -0.67
129S1/SvImJ m 3.76 0.661   8 0.234 0.176 3.05, 4.92 -0.89
A/J f 11.9 4.35   8 1.54 0.364 6.7, 20.7 0.15
A/J m 21.8 4.23   8 1.5 0.194 16.2, 28.5 1.07
AKR/J f 40.4 11.9   8 4.22 0.296 14.1, 50.7 3.52
AKR/J m 33.3 3.98   8 1.41 0.12 26.3, 37.4 2.33
BALB/cByJ f 2.9 1.29   8 0.456 0.444 1.35, 5.44 -0.91
BALB/cByJ m 3.71 2.39   8 0.843 0.643 1.13, 7.43 -0.9
BTBR T+ Itpr3tf/J f 3.67 0.676   8 0.239 0.184 2.55, 4.6 -0.82
BTBR T+ Itpr3tf/J m 3.35 0.667   8 0.236 0.199 2.53, 4.25 -0.94
BUB/BnJ f 10.5 2.35   8 0.829 0.224 7.22, 13.8 -0.01
BUB/BnJ m 7.08 1.29   8 0.455 0.182 5.94, 9.98 -0.53
C3H/HeJ f 10.4 2.71   8 0.959 0.262 7.16, 14.2 -0.02
C3H/HeJ m 19.7 3.4   8 1.2 0.173 15.8, 25.6 0.84
C57BL/10J f 21.1 6.54   8 2.31 0.31 11.0, 31.0 1.24
C57BL/10J m 20.2 5.46   8 1.93 0.27 13.6, 29.4 0.9
C57BL/6J f 15.0 3.18   8 1.12 0.212 9.98, 19.4 0.52
C57BL/6J m 19.6 4.97   8 1.76 0.254 11.4, 27.7 0.83
C57BLKS/J f 15.0 3.53   8 1.25 0.236 8.72, 19.4 0.52
C57BLKS/J m 12.7 1.5   8 0.53 0.118 10.1, 14.9 0.08
C57BR/cdJ f 9.7 1.7   8 0.6 0.175 6.97, 11.9 -0.11
C57BR/cdJ m 12.7 1.91   8 0.675 0.15 10.6, 16.8 0.08
C57L/J f 7.9 2.11   8 0.745 0.267 5.97, 12.5 -0.32
C57L/J m 10.0 2.51   8 0.889 0.251 6.43, 14.2 -0.21
CAST/EiJ f 4.34 4.34   6 1.77 1.0 0.15, 8.71 -0.74
CBA/J f 21.3 5.3   8 1.88 0.249 14.2, 28.6 1.26
CBA/J m 22.9 3.02   8 1.07 0.132 19.6, 27.5 1.19
DBA/2J f 20.6 3.45   8 1.22 0.168 15.4, 25.8 1.18
DBA/2J m 13.7 3.1   8 1.1 0.226 11.2, 18.9 0.19
FVB/NJ f 17.5 2.41   8 0.853 0.138 14.1, 21.1 0.81
FVB/NJ m 26.9 3.3   8 1.17 0.123 23.0, 32.3 1.63
KK/HlJ f 7.36 6.48   8 2.29 0.881 0.45, 15.4 -0.38
KK/HlJ m 4.74 2.25   8 0.797 0.476 1.75, 9.17 -0.79
LP/J f 6.27 6.55   8 2.32 1.05 1.5, 20.7 -0.51
LP/J m 12.6 7.68   8 2.71 0.609 3.79, 23.8 0.07
MOLF/EiJ f 0.00471 0.0081   7 0.00306 1.72 -1.25
MOLF/EiJ m 0.0107 0.0226   8 0.00799 2.1 -1.3
MRL/MpJ f 18.5 5.23   8 1.85 0.284 7.92, 23.0 0.93
MRL/MpJ m 17.2 3.71   8 1.31 0.215 11.4, 23.6 0.57
NOD.B10Sn-H2b/J f 10.4 2.31   9 0.77 0.221 6.66, 13.7 -0.02
NOD.B10Sn-H2b/J m 18.3 5.55   7 2.1 0.303 9.46, 24.8 0.69
NON/ShiLtJ f 15.4 3.16   8 1.12 0.205 10.9, 20.4 0.57
NON/ShiLtJ m 1.76 0.571   8 0.202 0.324 1.04, 2.65 -1.11
NZO/HlLtJ f 17.3 2.13   8 0.753 0.123 14.6, 20.5 0.79
NZO/HlLtJ m 22.4 5.88   8 2.08 0.263 15.6, 35.2 1.14
NZW/LacJ f 2.14 0.664   8 0.235 0.31 1.03, 3.27 -1.0
NZW/LacJ m 8.51 2.56   8 0.906 0.301 4.29, 12.4 -0.38
P/J f 4.85 1.67   8 0.592 0.345 1.97, 7.63 -0.68
P/J m 3.28 0.564   8 0.199 0.172 2.35, 4.06 -0.95
PL/J f 6.64 0.918   7 0.347 0.138 5.34, 7.82 -0.47
PL/J m 7.75 1.43   7 0.542 0.185 6.28, 10.0 -0.46
PWD/PhJ f 1.17 1.03   8 0.364 0.881 0.42, 3.59 -1.11
PWD/PhJ m 0.821 0.302   8 0.107 0.367 0.31, 1.19 -1.21
RIIIS/J f 6.24 0.798   8 0.282 0.128 5.56, 8.08 -0.52
RIIIS/J m 3.51 0.821   8 0.29 0.234 2.49, 5.17 -0.92
SJL/J f 1.82 0.508   8 0.18 0.279 1.15, 2.86 -1.04
SJL/J m 7.14 2.16   6 0.881 0.302 4.12, 10.2 -0.53
SM/J f 17.5 2.99   16 0.747 0.171 13.5, 24.2 0.81
SM/J m 26.6 4.36   8 1.54 0.164 19.5, 33.1 1.6
SWR/J f 1.26 0.757   8 0.268 0.601 0.48, 2.23 -1.1
SWR/J m 1.09 0.544   8 0.192 0.496 0.47, 1.94 -1.19
WSB/EiJ f 5.34 0.991   8 0.351 0.186 3.81, 6.75 -0.62
WSB/EiJ m 3.7 1.04   6 0.425 0.281 1.82, 4.73 -0.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.9638 1.253 7.4264 2.5011
129S1/SvImJ m 3.7625 1.253 6.2252 1.2998
A/J f 11.945 1.253 14.4077 9.4823
A/J m 21.7625 1.253 24.2252 19.2998
AKR/J f 40.35 1.253 42.8127 37.8873
AKR/J m 33.3375 1.253 35.8002 30.8748
BALB/cByJ f 2.9038 1.253 5.3664 0.4411
BALB/cByJ m 3.7075 1.253 6.1702 1.2448
BTBR T+ Itpr3tf/J f 3.6737 1.253 6.1364 1.2111
BTBR T+ Itpr3tf/J m 3.3488 1.253 5.8114 0.8861
BUB/BnJ f 10.475 1.253 12.9377 8.0123
BUB/BnJ m 7.0775 1.253 9.5402 4.6148
C3H/HeJ f 10.3513 1.253 12.8139 7.8886
C3H/HeJ m 19.6625 1.253 22.1252 17.1998
C57BL/10J f 21.1375 1.253 23.6002 18.6748
C57BL/10J m 20.2 1.253 22.6627 17.7373
C57BL/6J f 14.96 1.253 17.4227 12.4973
C57BL/6J m 19.575 1.253 22.0377 17.1123
C57BLKS/J f 14.9775 1.253 17.4402 12.5148
C57BLKS/J m 12.6625 1.253 15.1252 10.1998
C57BR/cdJ f 9.7012 1.253 12.1639 7.2386
C57BR/cdJ m 12.7375 1.253 15.2002 10.2748
C57L/J f 7.9038 1.253 10.3664 5.4411
C57L/J m 10.0163 1.253 12.4789 7.5536
CBA/J f 21.2625 1.253 23.7252 18.7998
CBA/J m 22.85 1.253 25.3127 20.3873
DBA/2J f 20.575 1.253 23.0377 18.1123
DBA/2J m 13.7375 1.253 16.2002 11.2748
FVB/NJ f 17.475 1.253 19.9377 15.0123
FVB/NJ m 26.875 1.253 29.3377 24.4123
KK/HlJ f 7.3575 1.253 9.8202 4.8948
KK/HlJ m 4.735 1.253 7.1977 2.2723
LP/J f 6.2675 1.253 8.7302 3.8048
LP/J m 12.5975 1.253 15.0602 10.1348
MOLF/EiJ f 0.0047 1.3395 2.6375 0.0
MOLF/EiJ m 0.0108 1.253 2.4734 0.0
MRL/MpJ f 18.4525 1.253 20.9152 15.9898
MRL/MpJ m 17.25 1.253 19.7127 14.7873
NOD.B10Sn-H2b/J f 10.4322 1.1813 12.7541 8.1104
NOD.B10Sn-H2b/J m 18.2943 1.3395 20.927 15.6615
NON/ShiLtJ f 15.4375 1.253 17.9002 12.9748
NON/ShiLtJ m 1.7625 1.253 4.2252 0.0
NZO/HlLtJ f 17.275 1.253 19.7377 14.8123
NZO/HlLtJ m 22.3875 1.253 24.8502 19.9248
NZW/LacJ f 2.1437 1.253 4.6064 0.0
NZW/LacJ m 8.5125 1.253 10.9752 6.0498
P/J f 4.8488 1.253 7.3114 2.3861
P/J m 3.2825 1.253 5.7452 0.8198
PL/J f 6.64 1.3395 9.2727 4.0073
PL/J m 7.7471 1.3395 10.3799 5.1144
PWD/PhJ f 1.1675 1.253 3.6302 0.0
PWD/PhJ m 0.8212 1.253 3.2839 0.0
RIIIS/J f 6.2425 1.253 8.7052 3.7798
RIIIS/J m 3.5113 1.253 5.9739 1.0486
SJL/J f 1.8175 1.253 4.2802 0.0
SJL/J m 7.1417 1.4468 9.9853 4.298
SM/J f 17.4688 0.886 19.2101 15.7274
SM/J m 26.6 1.253 29.0627 24.1373
SWR/J f 1.26 1.253 3.7227 0.0
SWR/J m 1.095 1.253 3.5577 0.0
WSB/EiJ f 5.3425 1.253 7.8052 2.8798
WSB/EiJ m 3.7 1.4468 6.5437 0.8563


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.3631 0.886 6.1045 2.6217
A/J both 16.8538 0.886 18.5951 15.1124
AKR/J both 36.8437 0.886 38.5851 35.1024
BALB/cByJ both 3.3056 0.886 5.047 1.5642
BTBR T+ Itpr3tf/J both 3.5113 0.886 5.2526 1.7699
BUB/BnJ both 8.7762 0.886 10.5176 7.0349
C3H/HeJ both 15.0069 0.886 16.7483 13.2655
C57BL/10J both 20.6687 0.886 22.4101 18.9274
C57BL/6J both 17.2675 0.886 19.0089 15.5261
C57BLKS/J both 13.82 0.886 15.5614 12.0786
C57BR/cdJ both 11.2194 0.886 12.9608 9.478
C57L/J both 8.96 0.886 10.7014 7.2186
CBA/J both 22.0563 0.886 23.7976 20.3149
DBA/2J both 17.1563 0.886 18.8976 15.4149
FVB/NJ both 22.175 0.886 23.9164 20.4336
KK/HlJ both 6.0462 0.886 7.7876 4.3049
LP/J both 9.4325 0.886 11.1739 7.6911
MOLF/EiJ both 0.0077 0.9171 1.8102 0.0
MRL/MpJ both 17.8513 0.886 19.5926 16.1099
NOD.B10Sn-H2b/J both 14.3633 0.893 16.1184 12.6081
NON/ShiLtJ both 8.6 0.886 10.3414 6.8586
NZO/HlLtJ both 19.8312 0.886 21.5726 18.0899
NZW/LacJ both 5.3281 0.886 7.0695 3.5867
P/J both 4.0656 0.886 5.807 2.3242
PL/J both 7.1936 0.9472 9.0552 5.3319
PWD/PhJ both 0.9944 0.886 2.7358 0.0
RIIIS/J both 4.8769 0.886 6.6183 3.1355
SJL/J both 4.4796 0.957 6.3605 2.5987
SM/J both 22.0344 0.7673 23.5425 20.5263
SWR/J both 1.1775 0.886 2.9189 0.0
WSB/EiJ both 4.5213 0.957 6.4022 2.6403




  GWAS USING LINEAR MIXED MODELS