Project measure / variable:   Petkova1   CD8_naive_M24

ID, description, units MPD:24259   CD8_naive_M24   CD8 T cells, naive, as percentage of total CD8 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, naive, as percentage of total CD8 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means34.2   % 39.3   %
Median of the strain means35.4   % 36.6   %
SD of the strain means± 19.9 ± 17.5
Coefficient of variation (CV)0.582 0.445
Min–max range of strain means3.20   –   61.2   % 8.69   –   68.4   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 949.0913 949.0913 5.4322 0.0214
strain 9 41633.0982 4625.8998 26.4766 < 0.0001
sex:strain 9 4075.8404 452.8712 2.592 0.0091
Residuals 121 21140.6991 174.7165


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 59.1 17.5   6 7.16 0.296 34.2, 78.3 1.25
129S1/SvImJ m 39.1 7.84   7 2.96 0.201 30.4, 49.8 -0.01
BALB/cByJ f 12.9 5.59   7 2.11 0.434 5.2, 22.0 -1.07
C3H/HeJ m 36.6 19.9   8 7.03 0.544 8.25, 61.4 -0.16
C57BL/10J f 5.72 6.42   8 2.27 1.12 -1.43
C57BL/10J m 8.69 5.98   6 2.44 0.688 2.18, 19.5 -1.75
C57BL/6J f 3.2 1.51   8 0.535 0.474 1.71, 6.35 -1.56
C57BL/6J m 18.4 9.2   8 3.25 0.501 7.22, 33.2 -1.2
C57BLKS/J f 42.0 15.6   6 6.39 0.373 16.8, 60.5 0.39
C57BLKS/J m 57.0 9.81   7 3.71 0.172 37.8, 66.3 1.01
C57BR/cdJ f 30.5 8.68   7 3.28 0.285 14.9, 41.5 -0.19
C57BR/cdJ m 35.9 22.8   9 7.59 0.633 0.7, 62.2 -0.2
LP/J f 42.8 16.9   8 5.98 0.395 7.71, 59.1 0.43
LP/J m 34.8 12.8   6 5.24 0.369 19.1, 50.4 -0.26
NON/ShiLtJ f 33.7 11.9   8 4.2 0.353 16.3, 54.3 -0.03
NON/ShiLtJ m 28.3 10.7   7 4.04 0.378 15.5, 44.7 -0.63
NZW/LacJ f 61.2 23.2   6 9.47 0.379 27.9, 87.0 1.36
NZW/LacJ m 68.4 12.0   7 4.54 0.175 51.8, 80.3 1.66
PWD/PhJ f 35.4 7.28   7 2.75 0.206 22.3, 42.9 0.06
PWD/PhJ m 50.6 19.0   7 7.19 0.376 17.3, 78.0 0.64
WSB/EiJ f 49.7 12.4   6 5.04 0.249 37.3, 66.8 0.78
WSB/EiJ m 54.8 8.75   7 3.31 0.159 41.3, 68.6 0.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 59.1333 5.3962 69.8166 48.4501
129S1/SvImJ m 39.0571 4.9959 48.9479 29.1663
C57BL/10J f 5.7237 4.6733 14.9757 0.0
C57BL/10J m 8.6933 5.3962 19.3766 0.0
C57BL/6J f 3.1963 4.6733 12.4482 0.0
C57BL/6J m 18.3688 4.6733 27.6207 9.1168
C57BLKS/J f 41.9833 5.3962 52.6666 31.3001
C57BLKS/J m 57.0429 4.9959 66.9337 47.1521
C57BR/cdJ f 30.4714 4.9959 40.3622 20.5806
C57BR/cdJ m 35.9333 4.406 44.6562 27.2105
LP/J f 42.7888 4.6733 52.0407 33.5368
LP/J m 34.7833 5.3962 45.4666 24.1001
NON/ShiLtJ f 33.6875 4.6733 42.9395 24.4355
NON/ShiLtJ m 28.2714 4.9959 38.1622 18.3806
NZW/LacJ f 61.2 5.3962 71.8833 50.5167
NZW/LacJ m 68.4429 4.9959 78.3337 58.5521
PWD/PhJ f 35.4 4.9959 45.2908 25.5092
PWD/PhJ m 50.6429 4.9959 60.5337 40.7521
WSB/EiJ f 49.7 5.3962 60.3833 39.0167
WSB/EiJ m 54.8429 4.9959 64.7337 44.9521


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 49.0952 3.6769 56.3747 41.8158
C57BL/10J both 7.2085 3.5693 14.2749 0.1422
C57BL/6J both 10.7825 3.3045 17.3246 4.2404
C57BLKS/J both 49.5131 3.6769 56.7925 42.2337
C57BR/cdJ both 33.2024 3.3306 39.7962 26.6085
LP/J both 38.786 3.5693 45.8524 31.7197
NON/ShiLtJ both 30.9795 3.4205 37.7512 24.2077
NZW/LacJ both 64.8214 3.6769 72.1009 57.542
PWD/PhJ both 43.0214 3.5327 50.0153 36.0276
WSB/EiJ both 52.2714 3.6769 59.5509 44.992




  GWAS USING LINEAR MIXED MODELS