Project measure / variable:   Petkova1   CD8_all_M24

ID, description, units MPD:24254   CD8_all_M24   CD8 T cells, as percentage of total lymphocytes   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, as percentage of total lymphocytes at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means9.15   % 14.4   %
Median of the strain means9.41   % 10.0   %
SD of the strain means± 5.12 ± 8.90
Coefficient of variation (CV)0.559 0.618
Min–max range of strain means2.14   –   21.4   % 4.93   –   31.8   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 865.0373 865.0373 20.6002 < 0.0001
strain 9 6281.7264 697.9696 16.6216 < 0.0001
sex:strain 9 582.3507 64.7056 1.5409 0.1411
Residuals 121 5080.9951 41.9917


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.41 3.16   6 1.29 0.335 4.47, 13.2 0.05
129S1/SvImJ m 9.41 3.0   7 1.13 0.319 4.77, 13.6 -0.56
BALB/cByJ f 8.5 4.67   7 1.76 0.549 0.79, 14.6 -0.13
C3H/HeJ m 26.8 5.81   8 2.05 0.217 20.0, 38.7 1.39
C57BL/10J f 2.14 2.07   8 0.734 0.969 0.74, 7.12 -1.37
C57BL/10J m 4.93 2.37   6 0.969 0.481 2.06, 8.18 -1.07
C57BL/6J f 11.8 5.99   8 2.12 0.506 6.2, 23.7 0.52
C57BL/6J m 17.6 6.16   8 2.18 0.349 10.5, 28.2 0.36
C57BLKS/J f 9.99 3.61   6 1.47 0.361 6.66, 15.5 0.16
C57BLKS/J m 22.3 18.0   7 6.81 0.808 8.03, 54.0 0.89
C57BR/cdJ f 21.4 11.6   7 4.38 0.542 4.99, 37.5 2.39
C57BR/cdJ m 31.8 10.4   9 3.47 0.327 17.8, 49.2 1.95
LP/J f 5.37 2.53   8 0.893 0.47 2.31, 9.62 -0.74
LP/J m 8.79 2.94   6 1.2 0.334 4.65, 13.2 -0.63
NON/ShiLtJ f 6.09 3.61   8 1.28 0.592 2.09, 13.0 -0.6
NON/ShiLtJ m 8.52 2.67   7 1.01 0.313 4.11, 12.9 -0.66
NZW/LacJ f 12.0 4.78   6 1.95 0.399 4.74, 16.8 0.56
NZW/LacJ m 11.4 6.46   7 2.44 0.569 1.15, 19.5 -0.34
PWD/PhJ f 4.4 2.41   7 0.909 0.547 1.26, 8.53 -0.93
PWD/PhJ m 7.0 2.21   7 0.834 0.315 2.68, 9.21 -0.83
WSB/EiJ f 9.54 3.22   6 1.31 0.337 6.78, 13.8 0.08
WSB/EiJ m 10.0 1.52   7 0.573 0.151 8.67, 13.1 -0.5


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.4083 2.6455 14.6458 4.1709
129S1/SvImJ m 9.4057 2.4492 14.2546 4.5568
C57BL/10J f 2.1412 2.2911 6.677 0.0
C57BL/10J m 4.935 2.6455 10.1724 0.0
C57BL/6J f 11.8325 2.2911 16.3683 7.2967
C57BL/6J m 17.6375 2.2911 22.1733 13.1017
C57BLKS/J f 9.9917 2.6455 15.2291 4.7542
C57BLKS/J m 22.2814 2.4492 27.1304 17.4325
C57BR/cdJ f 21.3771 2.4492 26.2261 16.5282
C57BR/cdJ m 31.8444 2.16 36.1208 27.5681
LP/J f 5.3737 2.2911 9.9095 0.838
LP/J m 8.7933 2.6455 14.0308 3.5559
NON/ShiLtJ f 6.0887 2.2911 10.6245 1.553
NON/ShiLtJ m 8.5171 2.4492 13.3661 3.6682
NZW/LacJ f 11.98 2.6455 17.2174 6.7426
NZW/LacJ m 11.36 2.4492 16.2089 6.5111
PWD/PhJ f 4.4 2.4492 9.2489 0.0
PWD/PhJ m 7.0 2.4492 11.8489 2.1511
WSB/EiJ f 9.5367 2.6455 14.7741 4.2992
WSB/EiJ m 10.0186 2.4492 14.8675 5.1696


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 9.407 1.8026 12.9757 5.8383
C57BL/10J both 3.5381 1.7498 7.0024 0.0739
C57BL/6J both 14.735 1.62 17.9423 11.5277
C57BLKS/J both 16.1365 1.8026 19.7053 12.5678
C57BR/cdJ both 26.6108 1.6328 29.8434 23.3782
LP/J both 7.0835 1.7498 10.5478 3.6193
NON/ShiLtJ both 7.3029 1.6769 10.6228 3.9831
NZW/LacJ both 11.67 1.8026 15.2387 8.1013
PWD/PhJ both 5.7 1.7319 9.1287 2.2713
WSB/EiJ both 9.7776 1.8026 13.3463 6.2089




  GWAS USING LINEAR MIXED MODELS