Project measure / variable:   Petkova1   CD8_all_M18

ID, description, units MPD:24253   CD8_all_M18   CD8 T cells, as percentage of total lymphocytes   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, as percentage of total lymphocytes at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means13.1   % 13.4   %
Median of the strain means12.0   % 12.5   %
SD of the strain means± 6.96 ± 5.84
Coefficient of variation (CV)0.532 0.437
Min–max range of strain means1.76   –   29.8   % 3.71   –   24.0   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.9481 2.9481 0.0926 0.7611
strain 22 9775.6406 444.3473 13.9617 < 0.0001
sex:strain 22 2364.3211 107.4691 3.3768 < 0.0001
Residuals 278 8847.66 31.8261


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 17.7 4.82   7 1.82 0.272 11.4, 25.4 0.66
129S1/SvImJ m 12.7 1.03   8 0.363 0.0808 11.2, 14.3 -0.12
A/J f 13.4 4.99   8 1.76 0.371 3.71, 19.1 0.04
BALB/cByJ f 7.4 3.09   8 1.09 0.418 0.31, 9.97 -0.82
BALB/cByJ m 12.5 2.42   6 0.99 0.193 10.4, 16.6 -0.15
BTBR T+ Itpr3tf/J f 16.1 5.42   8 1.92 0.336 5.12, 21.2 0.43
BTBR T+ Itpr3tf/J m 21.6 6.59   5 2.95 0.305 16.1, 33.0 1.41
BUB/BnJ f 9.76 6.67   8 2.36 0.684 3.13, 21.5 -0.48
BUB/BnJ m 7.09 1.27   6 0.52 0.18 5.11, 8.39 -1.08
C3H/HeJ f 14.5 2.72   8 0.963 0.188 9.98, 17.2 0.2
C3H/HeJ m 14.6 3.19   8 1.13 0.219 10.3, 19.6 0.21
C57BL/10J f 1.76 0.783   7 0.296 0.446 0.67, 2.86 -1.63
C57BL/10J m 4.31 0.0   1   0.0 0.0 4.31, 4.31 -1.55
C57BL/6J f 7.38 3.12   8 1.1 0.423 1.45, 12.1 -0.82
C57BL/6J m 8.51 3.39   7 1.28 0.398 2.94, 13.0 -0.83
C57BLKS/J f 10.4 2.39   7 0.902 0.23 6.89, 12.9 -0.39
C57BR/cdJ f 26.4 7.18   8 2.54 0.272 9.41, 32.4 1.91
C57BR/cdJ m 20.7 4.29   8 1.52 0.207 11.8, 27.1 1.25
C57L/J f 8.85 5.56   8 1.97 0.629 2.81, 19.4 -0.61
C57L/J m 16.9 4.33   6 1.77 0.257 12.3, 22.3 0.6
CBA/J f 20.2 8.69   8 3.07 0.431 6.4, 32.5 1.02
CBA/J m 20.5 1.78   6 0.727 0.0868 19.0, 23.4 1.22
DBA/2J f 11.0 2.48   7 0.937 0.225 7.71, 13.7 -0.3
DBA/2J m 7.44 1.92   8 0.68 0.259 4.89, 10.3 -1.02
FVB/NJ f 15.1 1.24   8 0.437 0.0818 13.5, 16.6 0.29
KK/HlJ f 27.5 17.5   7 6.61 0.637 13.5, 66.2 2.07
KK/HlJ m 12.2 2.53   7 0.957 0.208 9.2, 15.2 -0.2
LP/J f 5.39 2.92   7 1.1 0.542 0.25, 8.51 -1.11
LP/J m 10.8 4.47   8 1.58 0.414 0.64, 15.9 -0.44
MOLF/EiJ f 14.0 3.3   9 1.1 0.236 8.13, 20.5 0.13
MOLF/EiJ m 11.0 2.34   7 0.885 0.213 8.87, 15.2 -0.41
MRL/MpJ f 21.7 15.5   6 6.32 0.715 3.62, 45.8 1.24
MRL/MpJ m 21.6 6.66   8 2.35 0.308 8.46, 31.9 1.41
NOD.B10Sn-H2b/J f 3.63 2.52   7 0.954 0.696 0.97, 6.96 -1.36
NOD.B10Sn-H2b/J m 12.9 4.09   6 1.67 0.316 6.86, 17.7 -0.08
NON/ShiLtJ f 4.38 1.53   7 0.577 0.348 2.51, 6.75 -1.25
NON/ShiLtJ m 3.71 1.26   7 0.475 0.339 2.59, 6.11 -1.66
NZO/HlLtJ f 7.07 5.16   3 2.98 0.73 1.56, 11.8 -0.86
NZW/LacJ f 12.0 5.03   8 1.78 0.42 3.69, 19.7 -0.16
NZW/LacJ m 14.5 6.61   7 2.5 0.455 2.49, 20.5 0.19
P/J f 12.2 6.56   5 2.94 0.537 7.28, 23.2 -0.13
P/J m 8.46 3.79   4 1.89 0.447 4.47, 13.6 -0.84
PL/J f 29.8 5.93   4 2.96 0.199 22.2, 35.3 2.4
PL/J m 23.2 1.21   5 0.541 0.0522 21.6, 24.8 1.68
PWD/PhJ f 12.7 5.2   8 1.84 0.409 5.97, 22.2 -0.06
PWD/PhJ m 9.84 3.47   8 1.23 0.353 5.16, 15.9 -0.61
RIIIS/J m 8.31 1.28   8 0.452 0.154 7.09, 11.2 -0.87
SJL/J f 17.0 7.7   8 2.72 0.453 6.71, 31.8 0.56
SJL/J m 24.0 11.7   7 4.42 0.487 8.67, 43.8 1.82
SM/J f 9.35 2.37   7 0.895 0.253 5.9, 12.6 -0.54
SWR/J f 11.0 3.41   7 1.29 0.31 5.98, 15.1 -0.3
SWR/J m 15.0 1.36   6 0.555 0.091 13.6, 17.2 0.28
WSB/EiJ f 12.0 2.39   8 0.844 0.2 6.91, 14.2 -0.16
WSB/EiJ m 12.3 1.22   7 0.461 0.0991 10.6, 14.2 -0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 17.7286 2.1323 21.926 13.5311
129S1/SvImJ m 12.7 1.9946 16.6264 8.7736
BALB/cByJ f 7.3988 1.9946 11.3251 3.4724
BALB/cByJ m 12.5333 2.3031 17.0671 7.9996
BTBR T+ Itpr3tf/J f 16.14 1.9946 20.0664 12.2136
BTBR T+ Itpr3tf/J m 21.6 2.5229 26.5665 16.6335
BUB/BnJ f 9.7563 1.9946 13.6826 5.8299
BUB/BnJ m 7.0883 2.3031 11.6221 2.5546
C3H/HeJ f 14.4725 1.9946 18.3989 10.5461
C3H/HeJ m 14.55 1.9946 18.4764 10.6236
C57BL/6J f 7.3825 1.9946 11.3089 3.4561
C57BL/6J m 8.5114 2.1323 12.7089 4.314
C57BR/cdJ f 26.3763 1.9946 30.3026 22.4499
C57BR/cdJ m 20.7375 1.9946 24.6639 16.8111
C57L/J f 8.8488 1.9946 12.7751 4.9224
C57L/J m 16.8833 2.3031 21.4171 12.3496
CBA/J f 20.1625 1.9946 24.0889 16.2361
CBA/J m 20.5 2.3031 25.0338 15.9662
DBA/2J f 11.0271 2.1323 15.2246 6.8297
DBA/2J m 7.4387 1.9946 11.3651 3.5124
KK/HlJ f 27.4571 2.1323 31.6546 23.2597
KK/HlJ m 12.19 2.1323 16.3875 7.9925
LP/J f 5.3929 2.1323 9.5903 1.1954
LP/J m 10.7925 1.9946 14.7189 6.8661
MOLF/EiJ f 14.0256 1.8805 17.7274 10.3238
MOLF/EiJ m 10.9971 2.1323 15.1946 6.7997
MRL/MpJ f 21.6517 2.3031 26.1854 17.1179
MRL/MpJ m 21.5825 1.9946 25.5089 17.6561
NOD.B10Sn-H2b/J f 3.6271 2.1323 7.8246 0.0
NOD.B10Sn-H2b/J m 12.9383 2.3031 17.4721 8.4046
NON/ShiLtJ f 4.3843 2.1323 8.5817 0.1868
NON/ShiLtJ m 3.7114 2.1323 7.9089 0.0
NZW/LacJ f 11.97 1.9946 15.8964 8.0436
NZW/LacJ m 14.5414 2.1323 18.7389 10.344
P/J f 12.232 2.5229 17.1985 7.2655
P/J m 8.465 2.8207 14.0177 2.9123
PL/J f 29.8 2.8207 35.3527 24.2473
PL/J m 23.2 2.5229 28.1665 18.2335
PWD/PhJ f 12.7188 1.9946 16.6451 8.7924
PWD/PhJ m 9.8388 1.9946 13.7651 5.9124
SJL/J f 16.9888 1.9946 20.9151 13.0624
SJL/J m 23.9671 2.1323 28.1646 19.7697
SWR/J f 10.9886 2.1323 15.186 6.7911
SWR/J m 14.95 2.3031 19.4838 10.4162
WSB/EiJ f 11.9512 1.9946 15.8776 8.0249
WSB/EiJ m 12.3143 2.1323 16.5117 8.1168


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 15.2143 1.4599 18.0881 12.3405
BALB/cByJ both 9.966 1.5234 12.9648 6.9672
BTBR T+ Itpr3tf/J both 18.87 1.6081 22.0355 15.7045
BUB/BnJ both 8.4223 1.5234 11.4211 5.4235
C3H/HeJ both 14.5112 1.4104 17.2876 11.7349
C57BL/6J both 7.947 1.4599 10.8208 5.0732
C57BR/cdJ both 23.5569 1.4104 26.3332 20.7805
C57L/J both 12.866 1.5234 15.8648 9.8672
CBA/J both 20.3313 1.5234 23.3301 17.3324
DBA/2J both 9.2329 1.4599 12.1067 6.3591
KK/HlJ both 19.8236 1.5077 22.7916 16.8555
LP/J both 8.0927 1.4599 10.9665 5.2189
MOLF/EiJ both 12.5113 1.4215 15.3097 9.713
MRL/MpJ both 21.6171 1.5234 24.6159 18.6183
NOD.B10Sn-H2b/J both 8.2827 1.5693 11.372 5.1935
NON/ShiLtJ both 4.0479 1.5077 7.0159 1.0798
NZW/LacJ both 13.2557 1.4599 16.1295 10.3819
P/J both 10.3485 1.8922 14.0734 6.6236
PL/J both 26.5 1.8922 30.2249 22.7751
PWD/PhJ both 11.2788 1.4104 14.0551 8.5024
SJL/J both 20.4779 1.4599 23.3517 17.6041
SWR/J both 12.9693 1.5693 16.0585 9.88
WSB/EiJ both 12.1328 1.4599 15.0066 9.259




  GWAS USING LINEAR MIXED MODELS