Project measure / variable:   Petkova1   CD8_all_M12

ID, description, units MPD:24252   CD8_all_M12   CD8 T cells, as percentage of total lymphocytes   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, as percentage of total lymphocytes at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means16.7   % 15.1   %
Median of the strain means15.7   % 13.2   %
SD of the strain means± 7.96 ± 7.68
Coefficient of variation (CV)0.478 0.508
Min–max range of strain means1.84   –   39.3   % 3.64   –   34.5   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 356.1239 356.1239 21.1496 < 0.0001
strain 28 20473.2468 731.1874 43.4239 < 0.0001
sex:strain 28 4934.0484 176.216 10.4652 < 0.0001
Residuals 389 6550.1193 16.8384


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.8 3.12   8 1.1 0.166 13.6, 22.5 0.27
129S1/SvImJ m 4.45 0.806   8 0.285 0.181 3.53, 5.66 -1.39
A/J f 13.3 4.51   8 1.59 0.339 4.73, 20.5 -0.42
A/J m 16.4 3.5   8 1.24 0.214 12.5, 22.5 0.17
AKR/J m 10.7 6.35   5 2.84 0.592 0.6, 17.6 -0.57
BALB/cByJ f 9.5 1.39   8 0.493 0.147 7.86, 11.6 -0.9
BALB/cByJ m 13.3 3.13   8 1.11 0.235 7.38, 18.0 -0.24
BTBR T+ Itpr3tf/J f 23.0 3.49   8 1.23 0.152 18.4, 26.7 0.8
BTBR T+ Itpr3tf/J m 22.1 3.95   7 1.49 0.179 15.5, 26.8 0.91
BUB/BnJ f 10.4 1.77   6 0.721 0.171 8.14, 12.6 -0.79
BUB/BnJ m 6.4 1.84   9 0.615 0.288 4.09, 10.0 -1.13
C3H/HeJ f 13.8 3.43   8 1.21 0.249 8.0, 17.0 -0.36
C3H/HeJ m 13.9 3.38   8 1.2 0.243 9.57, 20.4 -0.16
C57BL/10J f 1.84 0.54   8 0.191 0.293 1.16, 2.61 -1.86
C57BL/10J m 3.64 1.91   7 0.723 0.525 2.2, 7.78 -1.49
C57BL/6J f 6.29 1.97   8 0.696 0.313 4.36, 9.76 -1.3
C57BL/6J m 12.3 4.62   8 1.64 0.376 5.31, 21.8 -0.37
C57BLKS/J f 13.7 3.07   8 1.09 0.224 10.5, 20.1 -0.37
C57BLKS/J m 14.4 1.45   8 0.513 0.101 12.2, 16.9 -0.09
C57BR/cdJ f 28.8 5.41   8 1.91 0.188 19.1, 36.6 1.52
C57BR/cdJ m 22.2 4.59   8 1.62 0.207 16.0, 28.0 0.92
C57L/J f 17.7 5.18   7 1.96 0.293 8.21, 23.6 0.13
C57L/J m 12.7 2.25   8 0.796 0.177 10.6, 16.7 -0.31
CAST/EiJ f 5.86 0.26   3 0.15 0.0444 5.6, 6.12 -1.36
CBA/J f 25.4 4.09   8 1.45 0.161 20.1, 30.7 1.1
CBA/J m 23.2 2.88   8 1.02 0.124 17.9, 26.3 1.05
DBA/2J f 11.1 2.0   6 0.817 0.18 8.96, 14.4 -0.7
DBA/2J m 7.2 1.02   7 0.387 0.142 5.48, 8.47 -1.03
FVB/NJ f 20.8 2.66   8 0.942 0.128 18.3, 26.6 0.52
FVB/NJ m 18.8 2.62   8 0.925 0.139 14.9, 22.4 0.48
KK/HlJ f 12.9 3.98   8 1.41 0.308 4.98, 16.6 -0.47
KK/HlJ m 12.7 2.04   8 0.72 0.161 9.79, 15.6 -0.31
LP/J f 14.7 5.52   7 2.08 0.375 7.34, 20.5 -0.25
LP/J m 12.9 6.74   8 2.38 0.524 1.52, 20.5 -0.29
MOLF/EiJ f 12.3 3.91   7 1.48 0.317 7.34, 19.6 -0.55
MOLF/EiJ m 11.9 2.38   9 0.795 0.201 8.44, 15.1 -0.42
MRL/MpJ f 10.7 7.73   8 2.73 0.724 4.35, 24.9 -0.75
MRL/MpJ m 34.1 10.5   8 3.7 0.307 18.5, 54.4 2.47
NON/ShiLtJ f 7.37 2.04   8 0.722 0.277 5.47, 11.8 -1.17
NON/ShiLtJ m 4.78 1.27   6 0.521 0.267 3.56, 6.76 -1.35
NZO/HlLtJ f 16.6 6.18   7 2.33 0.372 3.33, 23.0 -0.01
NZO/HlLtJ m 10.2 0.969   7 0.366 0.0949 9.15, 11.6 -0.64
NZW/LacJ f 25.0 3.51   8 1.24 0.14 17.2, 28.3 1.05
NZW/LacJ m 22.7 3.46   8 1.22 0.152 17.8, 27.3 0.99
P/J f 12.3 4.62   8 1.63 0.375 7.17, 19.2 -0.55
P/J m 7.39 1.12   7 0.424 0.152 6.13, 8.74 -1.01
PL/J f 39.3 8.49   7 3.21 0.216 21.6, 48.4 2.84
PL/J m 34.5 3.74   6 1.53 0.108 30.0, 39.5 2.53
PWD/PhJ f 26.8 9.02   8 3.19 0.337 6.3, 35.5 1.27
PWD/PhJ m 12.8 3.15   8 1.11 0.245 8.53, 19.0 -0.3
RIIIS/J f 23.4 2.44   8 0.863 0.104 20.7, 27.9 0.85
RIIIS/J m 14.4 1.47   8 0.52 0.102 12.2, 16.4 -0.09
SJL/J f 22.2 6.72   8 2.38 0.303 9.19, 30.1 0.7
SJL/J m 23.4 6.61   9 2.2 0.283 12.2, 33.0 1.08
SM/J f 16.6 1.91   8 0.677 0.115 13.9, 19.6 -0.01
SM/J m 13.0 1.8   8 0.635 0.138 9.43, 15.0 -0.27
SWR/J f 20.5 2.68   7 1.01 0.131 17.2, 24.3 0.48
SWR/J m 17.4 3.39   7 1.28 0.194 12.2, 21.7 0.3
WSB/EiJ f 18.8 2.21   8 0.782 0.118 15.2, 22.8 0.27
WSB/EiJ m 19.4 2.21   8 0.781 0.114 16.6, 23.7 0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.8375 1.4508 21.6899 15.9851
129S1/SvImJ m 4.45 1.4508 7.3024 1.5976
A/J f 13.2912 1.4508 16.1436 10.4389
A/J m 16.375 1.4508 19.2274 13.5226
BALB/cByJ f 9.5037 1.4508 12.3561 6.6514
BALB/cByJ m 13.3225 1.4508 16.1749 10.4701
BTBR T+ Itpr3tf/J f 22.9625 1.4508 25.8149 20.1101
BTBR T+ Itpr3tf/J m 22.0714 1.551 25.1207 19.0221
BUB/BnJ f 10.355 1.6752 13.6486 7.0614
BUB/BnJ m 6.4011 1.3678 9.0904 3.7119
C3H/HeJ f 13.8125 1.4508 16.6649 10.9601
C3H/HeJ m 13.9088 1.4508 16.7611 11.0564
C57BL/10J f 1.8437 1.4508 4.6961 0.0
C57BL/10J m 3.6429 1.551 6.6922 0.5935
C57BL/6J f 6.295 1.4508 9.1474 3.4426
C57BL/6J m 12.2888 1.4508 15.1411 9.4364
C57BLKS/J f 13.7125 1.4508 16.5649 10.8601
C57BLKS/J m 14.4 1.4508 17.2524 11.5476
C57BR/cdJ f 28.8 1.4508 31.6524 25.9476
C57BR/cdJ m 22.2125 1.4508 25.0649 19.3601
C57L/J f 17.7157 1.551 20.765 14.6664
C57L/J m 12.725 1.4508 15.5774 9.8726
CBA/J f 25.4375 1.4508 28.2899 22.5851
CBA/J m 23.175 1.4508 26.0274 20.3226
DBA/2J f 11.1367 1.6752 14.4303 7.843
DBA/2J m 7.2 1.551 10.2493 4.1507
FVB/NJ f 20.775 1.4508 23.6274 17.9226
FVB/NJ m 18.825 1.4508 21.6774 15.9726
KK/HlJ f 12.91 1.4508 15.7624 10.0576
KK/HlJ m 12.6613 1.4508 15.5136 9.8089
LP/J f 14.7014 1.551 17.7507 11.6521
LP/J m 12.8738 1.4508 15.7261 10.0214
MOLF/EiJ f 12.3486 1.551 15.3979 9.2993
MOLF/EiJ m 11.87 1.3678 14.5592 9.1808
MRL/MpJ f 10.67 1.4508 13.5224 7.8176
MRL/MpJ m 34.1125 1.4508 36.9649 31.2601
NON/ShiLtJ f 7.37 1.4508 10.2224 4.5176
NON/ShiLtJ m 4.78 1.6752 8.0736 1.4864
NZO/HlLtJ f 16.6043 1.551 19.6536 13.555
NZO/HlLtJ m 10.2057 1.551 13.255 7.1564
NZW/LacJ f 24.9625 1.4508 27.8149 22.1101
NZW/LacJ m 22.6875 1.4508 25.5399 19.8351
P/J f 12.3075 1.4508 15.1599 9.4551
P/J m 7.3857 1.551 10.435 4.3364
PL/J f 39.2571 1.551 42.3065 36.2078
PL/J m 34.5167 1.6752 37.8103 31.223
PWD/PhJ f 26.775 1.4508 29.6274 23.9226
PWD/PhJ m 12.8413 1.4508 15.6936 9.9889
RIIIS/J f 23.4125 1.4508 26.2649 20.5601
RIIIS/J m 14.3875 1.4508 17.2399 11.5351
SJL/J f 22.1988 1.4508 25.0511 19.3464
SJL/J m 23.4 1.3678 26.0892 20.7108
SM/J f 16.575 1.4508 19.4274 13.7226
SM/J m 13.0163 1.4508 15.8686 10.1639
SWR/J f 20.4714 1.551 23.5207 17.4221
SWR/J m 17.4286 1.551 20.4779 14.3793
WSB/EiJ f 18.7875 1.4508 21.6399 15.9351
WSB/EiJ m 19.45 1.4508 22.3024 16.5976


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.6438 1.0259 13.6607 9.6268
A/J both 14.8331 1.0259 16.8501 12.8162
BALB/cByJ both 11.4131 1.0259 13.4301 9.3962
BTBR T+ Itpr3tf/J both 22.517 1.0619 24.6047 20.4292
BUB/BnJ both 8.3781 1.0814 10.5041 6.252
C3H/HeJ both 13.8606 1.0259 15.8776 11.8437
C57BL/10J both 2.7433 1.0619 4.831 0.6556
C57BL/6J both 9.2919 1.0259 11.3088 7.2749
C57BLKS/J both 14.0563 1.0259 16.0732 12.0393
C57BR/cdJ both 25.5062 1.0259 27.5232 23.4893
C57L/J both 15.2204 1.0619 17.3081 13.1326
CBA/J both 24.3063 1.0259 26.3232 22.2893
DBA/2J both 9.1683 1.1415 11.4126 6.9241
FVB/NJ both 19.8 1.0259 21.8169 17.7831
KK/HlJ both 12.7856 1.0259 14.8026 10.7687
LP/J both 13.7876 1.0619 15.8753 11.6999
MOLF/EiJ both 12.1093 1.034 14.1422 10.0764
MRL/MpJ both 22.3913 1.0259 24.4082 20.3743
NON/ShiLtJ both 6.075 1.1081 8.2535 3.8965
NZO/HlLtJ both 13.405 1.0967 15.5612 11.2488
NZW/LacJ both 23.825 1.0259 25.8419 21.8081
P/J both 9.8466 1.0619 11.9343 7.7589
PL/J both 36.8869 1.1415 39.1311 34.6427
PWD/PhJ both 19.8081 1.0259 21.8251 17.7912
RIIIS/J both 18.9 1.0259 20.9169 16.8831
SJL/J both 22.7994 0.997 24.7595 20.8393
SM/J both 14.7956 1.0259 16.8126 12.7787
SWR/J both 18.95 1.0967 21.1062 16.7938
WSB/EiJ both 19.1188 1.0259 21.1357 17.1018




  GWAS USING LINEAR MIXED MODELS