Project measure / variable:   Petkova1   CD8_all_M06

ID, description, units MPD:24251   CD8_all_M06   CD8 T cells, as percentage of total lymphocytes   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD8 T cells, as percentage of total lymphocytes at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means15.7   % 15.4   %
Median of the strain means16.1   % 15.3   %
SD of the strain means± 7.78 ± 8.93
Coefficient of variation (CV)0.495 0.581
Min–max range of strain means4.88   –   28.9   % 1.88   –   37.1   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 67.4256 67.4256 7.5011 0.0064
strain 30 27699.4317 923.3144 102.7183 < 0.0001
sex:strain 30 5184.8893 172.8296 19.2272 < 0.0001
Residuals 435 3910.1268 8.9888


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5.15 5.05   8 1.78 0.98 1.67, 15.7 -1.36
129S1/SvImJ m 5.82 0.31   8 0.11 0.0533 5.5, 6.31 -1.07
A/J f 13.7 4.88   8 1.73 0.355 3.17, 18.4 -0.26
A/J m 7.26 2.16   8 0.763 0.297 3.61, 11.0 -0.91
AKR/J f 28.4 7.16   8 2.53 0.253 13.5, 35.6 1.63
AKR/J m 15.3 3.92   8 1.38 0.256 8.01, 21.3 -0.01
BALB/cByJ f 14.6 2.6   8 0.919 0.178 11.2, 19.0 -0.14
BALB/cByJ m 15.2 3.27   8 1.16 0.215 7.77, 17.4 -0.02
BTBR T+ Itpr3tf/J f 25.4 1.93   8 0.682 0.076 22.7, 27.8 1.24
BTBR T+ Itpr3tf/J m 22.6 1.82   8 0.643 0.0804 20.2, 25.5 0.81
BUB/BnJ f 8.3 1.74   8 0.615 0.21 5.1, 9.88 -0.95
BUB/BnJ m 5.48 3.12   8 1.1 0.569 3.6, 13.1 -1.11
C3H/HeJ f 18.3 1.19   8 0.422 0.065 16.1, 19.6 0.33
C3H/HeJ m 18.1 3.94   8 1.39 0.218 12.0, 25.6 0.3
C57BL/10J f 5.04 1.27   8 0.449 0.252 3.41, 6.78 -1.37
C57BL/10J m 4.95 1.64   8 0.579 0.331 1.76, 6.55 -1.17
C57BL/6J f 16.0 4.45   8 1.57 0.278 8.0, 22.3 0.04
C57BL/6J m 7.42 2.72   8 0.963 0.367 3.98, 12.8 -0.89
C57BLKS/J f 12.3 2.17   8 0.768 0.177 9.1, 14.9 -0.44
C57BLKS/J m 17.5 1.79   8 0.632 0.102 15.0, 20.5 0.24
C57BR/cdJ f 21.0 4.01   8 1.42 0.191 13.5, 24.9 0.68
C57BR/cdJ m 25.0 2.42   8 0.856 0.0968 21.6, 27.5 1.08
C57L/J f 15.2 2.28   8 0.807 0.151 11.2, 18.0 -0.07
C57L/J m 9.88 2.6   8 0.918 0.263 6.51, 15.0 -0.62
CAST/EiJ f 7.72 2.33   6 0.951 0.302 5.55, 11.0 -1.03
CBA/J f 20.9 1.99   8 0.703 0.0951 18.1, 23.6 0.67
CBA/J m 16.9 2.48   8 0.876 0.147 13.2, 20.7 0.17
DBA/2J f 7.96 1.51   8 0.533 0.189 5.56, 9.82 -1.0
DBA/2J m 7.25 1.27   8 0.448 0.175 4.59, 8.67 -0.91
FVB/NJ f 21.9 1.53   8 0.541 0.0698 19.5, 23.6 0.79
FVB/NJ m 27.1 2.59   8 0.916 0.0958 23.6, 31.5 1.31
KK/HlJ f 7.68 5.97   8 2.11 0.778 1.64, 14.2 -1.03
KK/HlJ m 7.02 2.0   8 0.707 0.285 4.36, 10.0 -0.94
LP/J f 9.37 5.34   8 1.89 0.569 2.45, 15.0 -0.82
LP/J m 9.06 7.29   8 2.58 0.805 1.41, 21.1 -0.71
MOLF/EiJ f 22.4 2.73   7 1.03 0.122 18.8, 26.3 0.86
MOLF/EiJ m 17.2 1.76   8 0.624 0.103 14.8, 20.5 0.2
MRL/MpJ f 19.8 6.07   8 2.14 0.306 9.3, 29.5 0.53
MRL/MpJ m 37.1 3.55   8 1.25 0.0955 30.5, 41.9 2.43
NOD.B10Sn-H2b/J f 20.4 1.99   9 0.665 0.0976 17.6, 23.8 0.6
NOD.B10Sn-H2b/J m 17.8 2.05   7 0.775 0.115 15.1, 21.0 0.27
NON/ShiLtJ f 5.86 1.07   8 0.378 0.182 4.46, 7.32 -1.27
NON/ShiLtJ m 1.88 0.496   8 0.175 0.264 1.16, 2.48 -1.51
NZO/HlLtJ f 17.5 2.21   8 0.781 0.126 15.7, 22.4 0.23
NZO/HlLtJ m 12.5 1.07   8 0.38 0.086 10.0, 13.4 -0.32
NZW/LacJ f 4.88 1.94   8 0.684 0.396 1.91, 8.48 -1.39
NZW/LacJ m 5.55 1.19   8 0.42 0.214 4.19, 7.29 -1.1
P/J f 7.01 1.07   8 0.378 0.153 5.99, 8.59 -1.12
P/J m 27.8 2.09   8 0.739 0.0753 23.9, 31.2 1.39
PL/J f 26.6 2.83   7 1.07 0.106 22.5, 29.5 1.4
PL/J m 25.8 2.57   7 0.97 0.0993 21.3, 29.1 1.17
PWD/PhJ f 27.3 1.15   8 0.406 0.042 24.8, 28.4 1.49
PWD/PhJ m 24.0 3.32   8 1.17 0.138 18.3, 27.5 0.96
RIIIS/J f 24.6 1.97   8 0.696 0.0801 20.8, 27.3 1.14
RIIIS/J m 16.9 1.45   8 0.511 0.0856 15.1, 19.9 0.17
SJL/J f 28.9 1.97   8 0.696 0.0682 25.5, 31.3 1.69
SJL/J m 31.5 6.29   6 2.57 0.2 24.7, 39.6 1.8
SM/J f 16.3 1.26   16 0.315 0.0774 13.9, 18.0 0.08
SM/J m 16.9 1.92   8 0.68 0.114 14.9, 19.8 0.17
SWR/J f 5.15 1.62   8 0.572 0.314 1.78, 6.76 -1.36
SWR/J m 5.7 1.59   8 0.562 0.279 3.08, 7.48 -1.08
WSB/EiJ f 17.2 1.79   8 0.632 0.104 14.9, 20.2 0.19
WSB/EiJ m 14.3 1.87   6 0.765 0.131 10.8, 16.4 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5.1513 1.06 7.2346 3.0679
129S1/SvImJ m 5.8212 1.06 7.9046 3.7379
A/J f 13.7337 1.06 15.8171 11.6504
A/J m 7.2625 1.06 9.3459 5.1791
AKR/J f 28.35 1.06 30.4334 26.2666
AKR/J m 15.3013 1.06 17.3846 13.2179
BALB/cByJ f 14.65 1.06 16.7334 12.5666
BALB/cByJ m 15.1837 1.06 17.2671 13.1004
BTBR T+ Itpr3tf/J f 25.3625 1.06 27.4459 23.2791
BTBR T+ Itpr3tf/J m 22.6125 1.06 24.6959 20.5291
BUB/BnJ f 8.2975 1.06 10.3809 6.2141
BUB/BnJ m 5.4763 1.06 7.5596 3.3929
C3H/HeJ f 18.3375 1.06 20.4209 16.2541
C3H/HeJ m 18.0875 1.06 20.1709 16.0041
C57BL/10J f 5.035 1.06 7.1184 2.9516
C57BL/10J m 4.9463 1.06 7.0296 2.8629
C57BL/6J f 16.025 1.06 18.1084 13.9416
C57BL/6J m 7.4225 1.06 9.5059 5.3391
C57BLKS/J f 12.3025 1.06 14.3859 10.2191
C57BLKS/J m 17.5 1.06 19.5834 15.4166
C57BR/cdJ f 21.0 1.06 23.0834 18.9166
C57BR/cdJ m 25.025 1.06 27.1084 22.9416
C57L/J f 15.175 1.06 17.2584 13.0916
C57L/J m 9.8825 1.06 11.9659 7.7991
CBA/J f 20.925 1.06 23.0084 18.8416
CBA/J m 16.875 1.06 18.9584 14.7916
DBA/2J f 7.9637 1.06 10.0471 5.8804
DBA/2J m 7.2537 1.06 9.3371 5.1704
FVB/NJ f 21.9125 1.06 23.9959 19.8291
FVB/NJ m 27.05 1.06 29.1334 24.9666
KK/HlJ f 7.6838 1.06 9.7671 5.6004
KK/HlJ m 7.0175 1.06 9.1009 4.9341
LP/J f 9.3737 1.06 11.4571 7.2904
LP/J m 9.06 1.06 11.1434 6.9766
MOLF/EiJ f 22.4429 1.1332 24.6701 20.2157
MOLF/EiJ m 17.2 1.06 19.2834 15.1166
MRL/MpJ f 19.8375 1.06 21.9209 17.7541
MRL/MpJ m 37.1375 1.06 39.2209 35.0541
NOD.B10Sn-H2b/J f 20.4333 0.9994 22.3975 18.4691
NOD.B10Sn-H2b/J m 17.8286 1.1332 20.0558 15.6014
NON/ShiLtJ f 5.8625 1.06 7.9459 3.7791
NON/ShiLtJ m 1.8775 1.06 3.9609 0.0
NZO/HlLtJ f 17.5 1.06 19.5834 15.4166
NZO/HlLtJ m 12.4875 1.06 14.5709 10.4041
NZW/LacJ f 4.8837 1.06 6.9671 2.8004
NZW/LacJ m 5.5525 1.06 7.6359 3.4691
P/J f 7.005 1.06 9.0884 4.9216
P/J m 27.775 1.06 29.8584 25.6916
PL/J f 26.6429 1.1332 28.8701 24.4157
PL/J m 25.8429 1.1332 28.0701 23.6157
PWD/PhJ f 27.325 1.06 29.4084 25.2416
PWD/PhJ m 24.0 1.06 26.0834 21.9166
RIIIS/J f 24.5625 1.06 26.6459 22.4791
RIIIS/J m 16.8875 1.06 18.9709 14.8041
SJL/J f 28.875 1.06 30.9584 26.7916
SJL/J m 31.5333 1.224 33.939 29.1277
SM/J f 16.3062 0.7495 17.7794 14.8331
SM/J m 16.875 1.06 18.9584 14.7916
SWR/J f 5.1537 1.06 7.2371 3.0704
SWR/J m 5.695 1.06 7.7784 3.6116
WSB/EiJ f 17.25 1.06 19.3334 15.1666
WSB/EiJ m 14.35 1.224 16.7557 11.9443


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.4862 0.7495 6.9594 4.0131
A/J both 10.4981 0.7495 11.9713 9.025
AKR/J both 21.8256 0.7495 23.2988 20.3525
BALB/cByJ both 14.9169 0.7495 16.39 13.4437
BTBR T+ Itpr3tf/J both 23.9875 0.7495 25.4607 22.5143
BUB/BnJ both 6.8869 0.7495 8.36 5.4137
C3H/HeJ both 18.2125 0.7495 19.6857 16.7393
C57BL/10J both 4.9906 0.7495 6.4638 3.5175
C57BL/6J both 11.7237 0.7495 13.1969 10.2506
C57BLKS/J both 14.9012 0.7495 16.3744 13.4281
C57BR/cdJ both 23.0125 0.7495 24.4857 21.5393
C57L/J both 12.5287 0.7495 14.0019 11.0556
CBA/J both 18.9 0.7495 20.3732 17.4268
DBA/2J both 7.6087 0.7495 9.0819 6.1356
FVB/NJ both 24.4812 0.7495 25.9544 23.0081
KK/HlJ both 7.3506 0.7495 8.8238 5.8775
LP/J both 9.2169 0.7495 10.69 7.7437
MOLF/EiJ both 19.8214 0.7758 21.3463 18.2966
MRL/MpJ both 28.4875 0.7495 29.9607 27.0143
NOD.B10Sn-H2b/J both 19.131 0.7555 20.6158 17.6462
NON/ShiLtJ both 3.87 0.7495 5.3432 2.3968
NZO/HlLtJ both 14.9937 0.7495 16.4669 13.5206
NZW/LacJ both 5.2181 0.7495 6.6913 3.745
P/J both 17.39 0.7495 18.8632 15.9168
PL/J both 26.2429 0.8013 27.8177 24.668
PWD/PhJ both 25.6625 0.7495 27.1357 24.1893
RIIIS/J both 20.725 0.7495 22.1982 19.2518
SJL/J both 30.2042 0.8096 31.7954 28.613
SM/J both 16.5906 0.6491 17.8664 15.3148
SWR/J both 5.4244 0.7495 6.8975 3.9512
WSB/EiJ both 15.8 0.8096 17.3912 14.2088




  GWAS USING LINEAR MIXED MODELS