Project measure / variable:   Petkova1   CD4_mem_effector_M24

ID, description, units MPD:24244   CD4_mem_effector_M24   CD4 T cells, effector memory, as percentage of total CD4 T cells   [%]  at age 24mo  
Data set, strains Petkova1   inbred   12 strains     sex: both     age: 104wks
Procedure immune cell quantification
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Petkova1 - CD4 T cells, effector memory, as percentage of total CD4 T cells at age 24mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means34.9   % 25.3   %
Median of the strain means26.8   % 21.0   %
SD of the strain means± 15.8 ± 11.2
Coefficient of variation (CV)0.452 0.445
Min–max range of strain means18.7   –   64.9   % 14.6   –   44.9   %
Mean sample size per strain7.0   mice 7.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5295.5464 5295.5464 38.5635 < 0.0001
strain 9 23398.0263 2599.7807 18.9323 < 0.0001
sex:strain 9 2588.1824 287.5758 2.0942 0.035
Residuals 121 16615.7321 137.3201


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.4 19.4   6 7.93 0.564 17.0, 64.0 -0.03
129S1/SvImJ m 21.0 4.06   7 1.53 0.193 13.8, 25.9 -0.38
BALB/cByJ f 24.3 19.8   7 7.47 0.813 1.35, 56.9 -0.67
C3H/HeJ m 23.9 10.2   8 3.59 0.425 12.9, 39.0 -0.12
C57BL/10J f 54.7 19.5   8 6.89 0.356 16.0, 77.1 1.25
C57BL/10J m 44.5 9.06   6 3.7 0.204 33.4, 59.2 1.71
C57BL/6J f 64.9 7.59   8 2.68 0.117 57.2, 79.1 1.9
C57BL/6J m 36.1 9.87   8 3.49 0.273 28.3, 58.7 0.96
C57BLKS/J f 18.7 4.5   6 1.84 0.241 12.8, 24.9 -1.03
C57BLKS/J m 14.9 1.54   7 0.582 0.104 12.8, 17.2 -0.92
C57BR/cdJ f 24.1 7.55   7 2.86 0.313 17.5, 40.1 -0.69
C57BR/cdJ m 20.2 14.2   9 4.72 0.701 8.77, 55.8 -0.45
LP/J f 26.8 16.5   8 5.82 0.615 7.95, 52.6 -0.51
LP/J m 21.2 13.7   6 5.59 0.645 10.5, 47.0 -0.36
NON/ShiLtJ f 53.0 4.01   8 1.42 0.0757 48.5, 58.7 1.14
NON/ShiLtJ m 44.9 7.1   7 2.68 0.158 36.1, 59.0 1.75
NZW/LacJ f 25.6 16.6   6 6.77 0.648 12.3, 56.6 -0.59
NZW/LacJ m 20.6 14.6   7 5.54 0.711 7.37, 42.4 -0.41
PWD/PhJ f 37.9 17.2   7 6.48 0.452 23.9, 69.2 0.19
PWD/PhJ m 14.6 5.32   7 2.01 0.363 9.39, 22.9 -0.95
WSB/EiJ f 19.9 9.26   6 3.78 0.465 13.1, 35.2 -0.95
WSB/EiJ m 16.0 4.86   7 1.84 0.304 10.9, 23.4 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.4333 4.784 43.9045 24.9621
129S1/SvImJ m 20.9857 4.4291 29.7543 12.2171
C57BL/10J f 54.75 4.1431 62.9523 46.5477
C57BL/10J m 44.4833 4.784 53.9545 35.0121
C57BL/6J f 64.9375 4.1431 73.1398 56.7352
C57BL/6J m 36.15 4.1431 44.3523 27.9477
C57BLKS/J f 18.6667 4.784 28.1379 9.1955
C57BLKS/J m 14.8857 4.4291 23.6543 6.1171
C57BR/cdJ f 24.1286 4.4291 32.8972 15.3599
C57BR/cdJ m 20.1967 3.9061 27.9299 12.4635
LP/J f 26.7937 4.1431 34.996 18.5915
LP/J m 21.2167 4.784 30.6879 11.7455
NON/ShiLtJ f 52.975 4.1431 61.1773 44.7727
NON/ShiLtJ m 44.8571 4.4291 53.6258 36.0885
NZW/LacJ f 25.6 4.784 35.0712 16.1288
NZW/LacJ m 20.6129 4.4291 29.3815 11.8442
PWD/PhJ f 37.9143 4.4291 46.6829 29.1457
PWD/PhJ m 14.6414 4.4291 23.4101 5.8728
WSB/EiJ f 19.9167 4.784 29.3879 10.4455
WSB/EiJ m 15.9714 4.4291 24.7401 7.2028


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.7095 3.2597 34.1631 21.256
C57BL/10J both 49.6167 3.1643 55.8813 43.3521
C57BL/6J both 50.5437 2.9296 56.3436 44.7439
C57BLKS/J both 16.7762 3.2597 23.2297 10.3227
C57BR/cdJ both 22.1626 2.9528 28.0084 16.3169
LP/J both 24.0052 3.1643 30.2698 17.7406
NON/ShiLtJ both 48.9161 3.0324 54.9195 42.9126
NZW/LacJ both 23.1064 3.2597 29.56 16.6529
PWD/PhJ both 26.2779 3.1319 32.4782 20.0775
WSB/EiJ both 17.944 3.2597 24.3976 11.4905




  GWAS USING LINEAR MIXED MODELS