Project measure / variable:   Petkova1   CD4_mem_effector_M18

ID, description, units MPD:24243   CD4_mem_effector_M18   CD4 T cells, effector memory, as percentage of total CD4 T cells   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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Petkova1 - CD4 T cells, effector memory, as percentage of total CD4 T cells at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means25.6   % 18.0   %
Median of the strain means19.7   % 14.5   %
SD of the strain means± 15.2 ± 8.65
Coefficient of variation (CV)0.595 0.481
Min–max range of strain means6.17   –   60.3   % 6.52   –   39.4   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5591.6574 5591.6574 62.4803 < 0.0001
strain 22 38532.034 1751.4561 19.5705 < 0.0001
sex:strain 22 7954.4162 361.5644 4.0401 < 0.0001
Residuals 278 24879.5319 89.4947


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 19.7 10.0   7 3.79 0.509 12.5, 41.2 -0.39
129S1/SvImJ m 12.6 1.72   8 0.607 0.136 10.6, 15.6 -0.62
A/J f 12.4 3.18   8 1.12 0.257 8.98, 18.2 -0.87
BALB/cByJ f 20.6 9.03   8 3.19 0.439 11.8, 37.5 -0.33
BALB/cByJ m 11.8 1.9   6 0.774 0.161 9.04, 14.8 -0.71
BTBR T+ Itpr3tf/J f 16.4 7.07   8 2.5 0.432 11.3, 32.9 -0.6
BTBR T+ Itpr3tf/J m 14.3 4.04   5 1.81 0.283 9.57, 20.0 -0.42
BUB/BnJ f 24.4 14.4   8 5.1 0.591 13.1, 53.0 -0.08
BUB/BnJ m 19.3 8.56   6 3.5 0.444 12.5, 35.7 0.15
C3H/HeJ f 19.6 5.53   8 1.95 0.283 11.3, 26.3 -0.39
C3H/HeJ m 14.2 4.88   8 1.72 0.344 9.78, 23.3 -0.44
C57BL/10J f 47.4 8.66   7 3.27 0.183 38.8, 61.2 1.43
C57BL/10J m 33.1 0.0   1   0.0 0.0 33.1, 33.1 1.75
C57BL/6J f 30.7 6.03   8 2.13 0.196 23.3, 40.3 0.33
C57BL/6J m 27.7 13.1   7 4.95 0.473 11.1, 50.8 1.12
C57BLKS/J f 11.7 2.96   7 1.12 0.252 6.96, 15.7 -0.91
C57BR/cdJ f 18.2 6.44   8 2.28 0.354 7.85, 28.3 -0.49
C57BR/cdJ m 14.5 3.23   8 1.14 0.223 9.4, 20.1 -0.4
C57L/J f 38.8 17.6   8 6.22 0.454 20.6, 64.6 0.87
C57L/J m 17.0 4.36   6 1.78 0.256 10.5, 22.2 -0.11
CBA/J f 17.3 8.51   8 3.01 0.492 7.29, 28.5 -0.55
CBA/J m 8.89 2.68   6 1.09 0.302 6.11, 13.5 -1.05
DBA/2J f 32.0 13.1   7 4.94 0.408 21.3, 60.8 0.42
DBA/2J m 20.7 3.91   8 1.38 0.189 15.6, 28.0 0.31
FVB/NJ f 7.51 2.6   8 0.918 0.346 4.15, 12.7 -1.19
KK/HlJ f 31.2 10.7   7 4.05 0.344 17.4, 46.9 0.37
KK/HlJ m 27.3 5.69   7 2.15 0.209 17.7, 36.2 1.08
LP/J f 12.9 8.03   7 3.04 0.623 6.11, 28.4 -0.83
LP/J m 20.7 18.0   8 6.37 0.87 4.99, 51.5 0.31
MOLF/EiJ f 18.4 7.37   9 2.46 0.4 8.98, 28.9 -0.47
MOLF/EiJ m 17.0 5.54   7 2.09 0.325 10.6, 24.7 -0.11
MRL/MpJ f 32.6 15.8   6 6.46 0.485 19.7, 60.1 0.46
MRL/MpJ m 11.6 5.27   8 1.86 0.455 4.16, 22.0 -0.74
NOD.B10Sn-H2b/J f 60.3 12.0   7 4.54 0.199 40.1, 70.8 2.28
NOD.B10Sn-H2b/J m 39.4 14.9   6 6.1 0.379 25.0, 59.4 2.48
NON/ShiLtJ f 57.5 8.63   7 3.26 0.15 44.2, 72.5 2.09
NON/ShiLtJ m 28.1 12.6   7 4.77 0.449 8.6, 46.1 1.17
NZO/HlLtJ f 44.6 16.2   3 9.35 0.363 26.0, 55.5 1.25
NZW/LacJ f 6.17 5.89   8 2.08 0.956 2.75, 20.5 -1.28
NZW/LacJ m 10.6 10.4   7 3.94 0.984 3.76, 33.4 -0.85
P/J f 28.9 15.1   5 6.77 0.523 14.9, 50.4 0.22
P/J m 28.7 7.32   4 3.66 0.255 22.1, 36.9 1.24
PL/J f 19.1 3.07   4 1.53 0.16 15.5, 23.0 -0.43
PL/J m 13.0 4.2   5 1.88 0.322 9.23, 18.5 -0.58
PWD/PhJ f 12.0 7.25   8 2.56 0.603 0.95, 25.2 -0.89
PWD/PhJ m 7.9 4.86   8 1.72 0.615 4.61, 19.0 -1.16
RIIIS/J m 10.8 8.61   8 3.04 0.796 5.04, 31.8 -0.83
SJL/J f 55.5 11.8   8 4.17 0.212 37.6, 70.0 1.96
SJL/J m 23.8 12.3   7 4.66 0.519 10.8, 46.5 0.67
SM/J f 21.2 7.07   7 2.67 0.333 14.5, 35.1 -0.29
SWR/J f 17.7 17.2   7 6.51 0.974 0.11, 50.5 -0.52
SWR/J m 9.93 4.66   6 1.9 0.469 3.52, 16.4 -0.93
WSB/EiJ f 7.83 3.36   8 1.19 0.429 5.4, 15.0 -1.17
WSB/EiJ m 6.52 1.58   7 0.596 0.242 3.92, 8.57 -1.32


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 19.7 3.5756 26.7387 12.6613
129S1/SvImJ m 12.6375 3.3447 19.2216 6.0534
BALB/cByJ f 20.5625 3.3447 27.1466 13.9784
BALB/cByJ m 11.7567 3.8621 19.3593 4.154
BTBR T+ Itpr3tf/J f 16.3625 3.3447 22.9466 9.7784
BTBR T+ Itpr3tf/J m 14.274 4.2307 22.6023 5.9457
BUB/BnJ f 24.45 3.3447 31.0341 17.8659
BUB/BnJ m 19.2667 3.8621 26.8693 11.664
C3H/HeJ f 19.5625 3.3447 26.1466 12.9784
C3H/HeJ m 14.1888 3.3447 20.7729 7.6046
C57BL/6J f 30.75 3.3447 37.3341 24.1659
C57BL/6J m 27.6714 3.5756 34.7101 20.6327
C57BR/cdJ f 18.2063 3.3447 24.7904 11.6221
C57BR/cdJ m 14.5 3.3447 21.0841 7.9159
C57L/J f 38.7625 3.3447 45.3466 32.1784
C57L/J m 17.0 3.8621 24.6027 9.3973
CBA/J f 17.3113 3.3447 23.8954 10.7271
CBA/J m 8.8883 3.8621 16.491 1.2857
DBA/2J f 32.0286 3.5756 39.0673 24.9899
DBA/2J m 20.6625 3.3447 27.2466 14.0784
KK/HlJ f 31.1714 3.5756 38.2101 24.1327
KK/HlJ m 27.2571 3.5756 34.2958 20.2184
LP/J f 12.9029 3.5756 19.9416 5.8642
LP/J m 20.705 3.3447 27.2891 14.1209
MOLF/EiJ f 18.4422 3.1534 24.6498 12.2347
MOLF/EiJ m 17.0429 3.5756 24.0816 10.0042
MRL/MpJ f 32.65 3.8621 40.2527 25.0473
MRL/MpJ m 11.5813 3.3447 18.1654 4.9971
NOD.B10Sn-H2b/J f 60.3 3.5756 67.3387 53.2613
NOD.B10Sn-H2b/J m 39.3667 3.8621 46.9693 31.764
NON/ShiLtJ f 57.5286 3.5756 64.5673 50.4899
NON/ShiLtJ m 28.1143 3.5756 35.153 21.0756
NZW/LacJ f 6.165 3.3447 12.7491 0.0
NZW/LacJ m 10.6029 3.5756 17.6416 3.5642
P/J f 28.94 4.2307 37.2683 20.6117
P/J m 28.725 4.7301 38.0363 19.4137
PL/J f 19.125 4.7301 28.4363 9.8137
PL/J m 13.046 4.2307 21.3743 4.7177
PWD/PhJ f 12.0113 3.3447 18.5954 5.4271
PWD/PhJ m 7.9025 3.3447 14.4866 1.3184
SJL/J f 55.4625 3.3447 62.0466 48.8784
SJL/J m 23.7571 3.5756 30.7958 16.7184
SWR/J f 17.67 3.5756 24.7087 10.6313
SWR/J m 9.9283 3.8621 17.531 2.3257
WSB/EiJ f 7.8262 3.3447 14.4104 1.2421
WSB/EiJ m 6.5243 3.5756 13.563 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 16.1688 2.4481 20.9878 11.3497
BALB/cByJ both 16.1596 2.5545 21.1883 11.1309
BTBR T+ Itpr3tf/J both 15.3182 2.6966 20.6265 10.01
BUB/BnJ both 21.8583 2.5545 26.887 16.8296
C3H/HeJ both 16.8756 2.365 21.5313 12.22
C57BL/6J both 29.2107 2.4481 34.0298 24.3916
C57BR/cdJ both 16.3531 2.365 21.0088 11.6975
C57L/J both 27.8812 2.5545 32.9099 22.8526
CBA/J both 13.0998 2.5545 18.1285 8.0711
DBA/2J both 26.3455 2.4481 31.1646 21.5265
KK/HlJ both 29.2143 2.5283 34.1914 24.2372
LP/J both 16.8039 2.4481 21.623 11.9849
MOLF/EiJ both 17.7425 2.3837 22.435 13.0501
MRL/MpJ both 22.1156 2.5545 27.1443 17.0869
NOD.B10Sn-H2b/J both 49.8333 2.6316 55.0137 44.653
NON/ShiLtJ both 42.8214 2.5283 47.7985 37.8443
NZW/LacJ both 8.3839 2.4481 13.203 3.5649
P/J both 28.8325 3.173 35.0787 22.5863
PL/J both 16.0855 3.173 22.3317 9.8393
PWD/PhJ both 9.9569 2.365 14.6125 5.3012
SJL/J both 39.6098 2.4481 44.4289 34.7908
SWR/J both 13.7992 2.6316 18.9795 8.6188
WSB/EiJ both 7.1753 2.4481 11.9943 2.3562




  GWAS USING LINEAR MIXED MODELS