Project measure / variable:   Petkova1   CD4_mem_effector_M12

ID, description, units MPD:24242   CD4_mem_effector_M12   CD4 T cells, effector memory, as percentage of total CD4 T cells   [%]  at age 12mo  
Data set, strains Petkova1   inbred   31 strains     sex: both     age: 52wks
Procedure immune cell quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Petkova1 - CD4 T cells, effector memory, as percentage of total CD4 T cells at age 12mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested30 strains30 strains
Mean of the strain means21.5   % 16.7   %
Median of the strain means17.1   % 14.7   %
SD of the strain means± 13.0 ± 7.74
Coefficient of variation (CV)0.606 0.464
Min–max range of strain means4.98   –   50.3   % 5.03   –   31.2   %
Mean sample size per strain7.6   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2882.4971 2882.4971 49.9702 < 0.0001
strain 28 42046.0295 1501.6439 26.0321 < 0.0001
sex:strain 28 9448.9005 337.4607 5.8501 < 0.0001
Residuals 389 22439.2075 57.6843


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.9 3.78   8 1.34 0.317 8.95, 20.5 -0.73
129S1/SvImJ m 20.0 2.52   8 0.892 0.126 17.8, 25.3 0.43
A/J f 11.7 2.8   8 0.989 0.24 8.11, 16.0 -0.75
A/J m 13.1 2.59   8 0.914 0.198 9.47, 16.9 -0.46
AKR/J m 22.1 8.03   5 3.59 0.363 12.2, 34.2 0.7
BALB/cByJ f 11.9 3.01   8 1.06 0.253 8.72, 16.4 -0.73
BALB/cByJ m 6.14 1.81   8 0.641 0.295 4.37, 9.29 -1.36
BTBR T+ Itpr3tf/J f 10.3 2.6   8 0.919 0.253 6.73, 14.6 -0.86
BTBR T+ Itpr3tf/J m 11.8 2.32   7 0.878 0.197 9.19, 15.2 -0.63
BUB/BnJ f 17.3 5.52   6 2.25 0.318 12.2, 26.6 -0.32
BUB/BnJ m 13.1 3.52   9 1.17 0.268 7.93, 17.7 -0.46
C3H/HeJ f 25.3 5.65   8 2.0 0.224 17.0, 35.5 0.3
C3H/HeJ m 24.0 5.28   8 1.87 0.22 18.2, 34.2 0.94
C57BL/10J f 46.7 12.8   8 4.53 0.275 31.8, 69.4 1.94
C57BL/10J m 31.0 8.12   7 3.07 0.262 19.2, 44.6 1.85
C57BL/6J f 37.9 14.2   8 5.03 0.375 16.9, 63.2 1.26
C57BL/6J m 16.3 4.67   8 1.65 0.285 10.0, 23.3 -0.05
C57BLKS/J f 16.9 3.05   8 1.08 0.18 12.1, 22.5 -0.35
C57BLKS/J m 12.9 1.08   8 0.382 0.0836 11.4, 14.3 -0.49
C57BR/cdJ f 15.3 2.47   8 0.875 0.162 12.7, 19.8 -0.47
C57BR/cdJ m 11.2 2.99   8 1.06 0.267 7.12, 17.0 -0.71
C57L/J f 30.8 11.6   7 4.37 0.375 16.3, 46.3 0.72
C57L/J m 24.1 3.75   8 1.33 0.156 19.1, 31.3 0.96
CAST/EiJ f 16.3 2.67   3 1.54 0.164 13.3, 18.4 -0.4
CBA/J f 10.3 1.75   8 0.618 0.17 7.83, 12.8 -0.86
CBA/J m 7.81 1.84   8 0.652 0.236 5.85, 11.2 -1.15
DBA/2J f 25.3 4.77   6 1.95 0.188 19.8, 33.7 0.3
DBA/2J m 16.3 3.23   7 1.22 0.198 14.0, 22.5 -0.05
FVB/NJ f 8.89 1.87   8 0.662 0.211 6.5, 12.5 -0.97
FVB/NJ m 13.6 5.36   8 1.9 0.394 8.69, 25.4 -0.4
KK/HlJ f 27.6 8.18   8 2.89 0.296 22.4, 46.8 0.47
KK/HlJ m 27.5 6.91   8 2.44 0.251 21.2, 42.9 1.4
LP/J f 19.6 15.6   7 5.91 0.795 5.55, 43.5 -0.14
LP/J m 21.6 20.0   8 7.07 0.925 5.03, 62.0 0.63
MOLF/EiJ f 45.2 8.36   7 3.16 0.185 36.9, 60.5 1.82
MOLF/EiJ m 22.5 13.5   9 4.48 0.597 9.36, 49.2 0.75
MRL/MpJ f 43.1 18.3   8 6.48 0.425 15.4, 63.7 1.66
MRL/MpJ m 12.2 3.56   8 1.26 0.291 7.06, 16.0 -0.58
NON/ShiLtJ f 50.3 8.67   8 3.07 0.172 38.1, 63.4 2.22
NON/ShiLtJ m 31.2 7.27   6 2.97 0.233 20.7, 37.7 1.87
NZO/HlLtJ f 21.8 12.7   7 4.8 0.583 14.8, 50.3 0.03
NZO/HlLtJ m 15.0 6.22   7 2.35 0.413 9.48, 25.9 -0.22
NZW/LacJ f 4.98 0.776   8 0.274 0.156 3.74, 6.26 -1.27
NZW/LacJ m 8.09 3.57   8 1.26 0.442 5.64, 16.2 -1.11
P/J f 11.3 5.3   8 1.87 0.471 5.45, 18.8 -0.78
P/J m 9.64 3.36   7 1.27 0.349 4.17, 13.2 -0.91
PL/J f 13.0 6.78   7 2.56 0.524 7.69, 27.2 -0.65
PL/J m 17.1 1.91   6 0.78 0.112 14.7, 19.2 0.05
PWD/PhJ f 12.5 10.5   8 3.72 0.842 4.96, 37.8 -0.69
PWD/PhJ m 5.03 1.53   8 0.541 0.304 3.26, 7.09 -1.51
RIIIS/J f 10.3 2.44   8 0.862 0.238 7.8, 14.3 -0.86
RIIIS/J m 11.2 5.23   8 1.85 0.469 5.62, 22.7 -0.71
SJL/J f 39.1 12.2   8 4.31 0.312 14.6, 53.3 1.36
SJL/J m 30.4 12.3   9 4.1 0.405 19.3, 55.8 1.77
SM/J f 18.8 2.38   8 0.842 0.127 14.9, 21.7 -0.2
SM/J m 25.7 8.99   8 3.18 0.35 7.73, 34.5 1.16
SWR/J f 22.8 11.2   7 4.22 0.489 11.7, 44.4 0.1
SWR/J m 14.3 2.76   7 1.04 0.192 11.1, 18.8 -0.31
WSB/EiJ f 6.55 1.01   8 0.355 0.153 5.22, 8.14 -1.15
WSB/EiJ m 5.86 1.31   8 0.464 0.224 4.03, 8.07 -1.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.9225 2.6852 17.2019 6.6431
129S1/SvImJ m 20.025 2.6852 25.3044 14.7456
A/J f 11.6525 2.6852 16.9319 6.3731
A/J m 13.0587 2.6852 18.3382 7.7793
BALB/cByJ f 11.8962 2.6852 17.1757 6.6168
BALB/cByJ m 6.145 2.6852 11.4244 0.8656
BTBR T+ Itpr3tf/J f 10.2725 2.6852 15.5519 4.9931
BTBR T+ Itpr3tf/J m 11.7829 2.8706 17.4268 6.1389
BUB/BnJ f 17.35 3.1007 23.4461 11.2539
BUB/BnJ m 13.1233 2.5317 18.1008 8.1459
C3H/HeJ f 25.2625 2.6852 30.5419 19.9831
C3H/HeJ m 23.9625 2.6852 29.2419 18.6831
C57BL/10J f 46.6875 2.6852 51.9669 41.4081
C57BL/10J m 30.9714 2.8706 36.6154 25.3275
C57BL/6J f 37.9375 2.6852 43.2169 32.6581
C57BL/6J m 16.35 2.6852 21.6294 11.0706
C57BLKS/J f 16.9 2.6852 22.1794 11.6206
C57BLKS/J m 12.925 2.6852 18.2044 7.6456
C57BR/cdJ f 15.275 2.6852 20.5544 9.9956
C57BR/cdJ m 11.2237 2.6852 16.5032 5.9443
C57L/J f 30.8 2.8706 36.4439 25.1561
C57L/J m 24.1125 2.6852 29.3919 18.8331
CBA/J f 10.2688 2.6852 15.5482 4.9893
CBA/J m 7.8063 2.6852 13.0857 2.5268
DBA/2J f 25.3 3.1007 31.3961 19.2039
DBA/2J m 16.3143 2.8706 21.9582 10.6704
FVB/NJ f 8.8925 2.6852 14.1719 3.6131
FVB/NJ m 13.6238 2.6852 18.9032 8.3443
KK/HlJ f 27.6 2.6852 32.8794 22.3206
KK/HlJ m 27.5125 2.6852 32.7919 22.2331
LP/J f 19.6471 2.8706 25.2911 14.0032
LP/J m 21.625 2.6852 26.9044 16.3456
MOLF/EiJ f 45.2143 2.8706 50.8582 39.5704
MOLF/EiJ m 22.5289 2.5317 27.5064 17.5514
MRL/MpJ f 43.1375 2.6852 48.4169 37.8581
MRL/MpJ m 12.2075 2.6852 17.4869 6.9281
NON/ShiLtJ f 50.325 2.6852 55.6044 45.0456
NON/ShiLtJ m 31.1833 3.1007 37.2795 25.0872
NZO/HlLtJ f 21.7857 2.8706 27.4296 16.1418
NZO/HlLtJ m 15.0471 2.8706 20.6911 9.4032
NZW/LacJ f 4.985 2.6852 10.2644 0.0
NZW/LacJ m 8.0875 2.6852 13.3669 2.8081
P/J f 11.2613 2.6852 16.5407 5.9818
P/J m 9.64 2.8706 15.2839 3.9961
PL/J f 12.9571 2.8706 18.6011 7.3132
PL/J m 17.1167 3.1007 23.2128 11.0205
PWD/PhJ f 12.5037 2.6852 17.7832 7.2243
PWD/PhJ m 5.0262 2.6852 10.3057 0.0
RIIIS/J f 10.2662 2.6852 15.5457 4.9868
RIIIS/J m 11.1525 2.6852 16.4319 5.8731
SJL/J f 39.05 2.6852 44.3294 33.7706
SJL/J m 30.3667 2.5317 35.3441 25.3892
SM/J f 18.7875 2.6852 24.0669 13.5081
SM/J m 25.7038 2.6852 30.9832 20.4243
SWR/J f 22.8286 2.8706 28.4725 17.1846
SWR/J m 14.3286 2.8706 19.9725 8.6846
WSB/EiJ f 6.55 2.6852 11.8294 1.2706
WSB/EiJ m 5.8625 2.6852 11.1419 0.5831


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 15.9737 1.8988 19.7069 12.2406
A/J both 12.3556 1.8988 16.0887 8.6225
BALB/cByJ both 9.0206 1.8988 12.7537 5.2875
BTBR T+ Itpr3tf/J both 11.0277 1.9654 14.8918 7.1635
BUB/BnJ both 15.2367 2.0015 19.1717 11.3016
C3H/HeJ both 24.6125 1.8988 28.3456 20.8794
C57BL/10J both 38.8295 1.9654 42.6936 34.9653
C57BL/6J both 27.1438 1.8988 30.8769 23.4106
C57BLKS/J both 14.9125 1.8988 18.6456 11.1794
C57BR/cdJ both 13.2494 1.8988 16.9825 9.5163
C57L/J both 27.4562 1.9654 31.3204 23.5921
CBA/J both 9.0375 1.8988 12.7706 5.3044
DBA/2J both 20.8071 2.1127 24.961 16.6533
FVB/NJ both 11.2581 1.8988 14.9912 7.525
KK/HlJ both 27.5563 1.8988 31.2894 23.8231
LP/J both 20.6361 1.9654 24.5002 16.7719
MOLF/EiJ both 33.8716 1.9138 37.6342 30.109
MRL/MpJ both 27.6725 1.8988 31.4056 23.9394
NON/ShiLtJ both 40.7542 2.0509 44.7864 36.722
NZO/HlLtJ both 18.4164 2.0299 22.4073 14.4256
NZW/LacJ both 6.5363 1.8988 10.2694 2.8031
P/J both 10.4506 1.9654 14.3148 6.5865
PL/J both 15.0369 2.1127 19.1907 10.8831
PWD/PhJ both 8.765 1.8988 12.4981 5.0319
RIIIS/J both 10.7094 1.8988 14.4425 6.9763
SJL/J both 34.7083 1.8453 38.3363 31.0804
SM/J both 22.2456 1.8988 25.9787 18.5125
SWR/J both 18.5786 2.0299 22.5694 14.5877
WSB/EiJ both 6.2062 1.8988 9.9394 2.4731




  GWAS USING LINEAR MIXED MODELS