Project measure / variable:   Petkova1   CD4_mem_effector_M06

ID, description, units MPD:24241   CD4_mem_effector_M06   CD4 T cells, effector memory, as percentage of total CD4 T cells   [%]  at age 6mo  
Data set, strains Petkova1   inbred   32 strains     sex: both     age: 26wks
Procedure immune cell quantification
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Petkova1 - CD4 T cells, effector memory, as percentage of total CD4 T cells at age 6mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested32 strains31 strains
Mean of the strain means14.9   % 14.5   %
Median of the strain means10.9   % 9.56   %
SD of the strain means± 11.1 ± 12.7
Coefficient of variation (CV)0.748 0.875
Min–max range of strain means2.96   –   42.4   % 3.30   –   59.3   %
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 16.6773 16.6773 0.4179 0.5183
strain 30 53925.3311 1797.511 45.0473 < 0.0001
sex:strain 30 15000.209 500.007 12.5306 < 0.0001
Residuals 435 17357.7093 39.9028


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.9 5.37   8 1.9 0.225 16.9, 34.8 0.81
129S1/SvImJ m 29.9 2.56   8 0.905 0.0856 25.5, 32.7 1.22
A/J f 22.0 3.73   8 1.32 0.169 17.5, 28.3 0.64
A/J m 25.3 2.38   8 0.84 0.0938 22.3, 28.3 0.85
AKR/J f 18.6 18.9   8 6.67 1.01 4.96, 52.9 0.33
AKR/J m 6.53 2.62   8 0.927 0.402 3.57, 11.9 -0.63
BALB/cByJ f 23.1 6.2   8 2.19 0.269 13.6, 33.8 0.74
BALB/cByJ m 5.83 1.19   8 0.42 0.204 4.17, 7.34 -0.68
BTBR T+ Itpr3tf/J f 5.36 1.29   8 0.456 0.24 3.74, 8.07 -0.86
BTBR T+ Itpr3tf/J m 6.66 0.779   8 0.275 0.117 5.83, 8.34 -0.62
BUB/BnJ f 17.9 5.36   8 1.9 0.299 7.73, 24.9 0.27
BUB/BnJ m 19.4 1.93   8 0.683 0.0998 17.0, 22.1 0.39
C3H/HeJ f 5.14 1.03   8 0.363 0.2 3.78, 6.66 -0.88
C3H/HeJ m 6.7 2.07   8 0.731 0.309 4.2, 10.3 -0.61
C57BL/10J f 10.5 3.68   8 1.3 0.351 5.2, 16.9 -0.39
C57BL/10J m 11.1 2.15   8 0.761 0.194 8.85, 14.8 -0.27
C57BL/6J f 16.4 3.84   8 1.36 0.234 11.1, 22.2 0.13
C57BL/6J m 6.56 2.43   8 0.859 0.371 4.23, 10.6 -0.63
C57BLKS/J f 10.4 2.65   8 0.936 0.255 7.7, 14.7 -0.4
C57BLKS/J m 7.16 1.0   8 0.355 0.14 5.93, 8.74 -0.58
C57BR/cdJ f 7.11 2.03   8 0.718 0.286 5.17, 11.4 -0.7
C57BR/cdJ m 10.1 1.42   8 0.502 0.14 7.89, 11.7 -0.35
C57L/J f 11.3 5.15   8 1.82 0.457 4.6, 16.9 -0.32
C57L/J m 8.11 2.1   8 0.742 0.259 4.26, 10.0 -0.5
CAST/EiJ f 6.57 1.03   6 0.422 0.157 5.19, 8.13 -0.75
CBA/J f 3.54 0.526   8 0.186 0.148 2.66, 4.27 -1.02
CBA/J m 9.56 3.62   8 1.28 0.379 5.52, 16.2 -0.39
DBA/2J f 13.0 5.41   8 1.91 0.416 7.33, 22.7 -0.17
DBA/2J m 15.0 2.45   8 0.865 0.163 10.6, 18.3 0.04
FVB/NJ f 4.82 0.925   8 0.327 0.192 3.72, 6.21 -0.9
FVB/NJ m 7.29 0.934   8 0.33 0.128 5.94, 9.15 -0.57
KK/HlJ f 36.2 24.1   8 8.53 0.666 12.3, 68.7 1.91
KK/HlJ m 8.76 3.78   8 1.34 0.432 6.26, 17.7 -0.45
LP/J f 34.8 20.2   8 7.14 0.58 6.23, 57.2 1.79
LP/J m 34.6 18.5   8 6.55 0.535 13.5, 62.4 1.59
MOLF/EiJ f 15.0 2.45   7 0.927 0.164 11.3, 18.7 0.01
MOLF/EiJ m 13.8 2.64   8 0.935 0.191 10.9, 17.5 -0.05
MRL/MpJ f 18.9 7.3   8 2.58 0.386 10.6, 33.7 0.36
MRL/MpJ m 16.6 3.38   8 1.19 0.204 10.9, 20.4 0.17
NOD.B10Sn-H2b/J f 7.64 1.75   9 0.584 0.229 5.54, 10.1 -0.65
NOD.B10Sn-H2b/J m 18.6 4.66   7 1.76 0.251 14.3, 28.4 0.32
NON/ShiLtJ f 21.6 6.51   8 2.3 0.301 10.7, 31.1 0.6
NON/ShiLtJ m 59.3 5.96   8 2.11 0.1 50.8, 66.7 3.54
NZO/HlLtJ f 7.57 1.58   8 0.559 0.209 5.69, 10.2 -0.66
NZO/HlLtJ m 10.2 3.97   8 1.4 0.389 4.75, 18.4 -0.34
NZW/LacJ f 39.4 9.05   8 3.2 0.23 24.5, 51.0 2.2
NZW/LacJ m 20.5 3.11   8 1.1 0.152 15.8, 24.4 0.47
P/J f 22.6 4.2   8 1.48 0.186 18.3, 30.6 0.69
P/J m 3.33 0.781   8 0.276 0.234 2.17, 4.47 -0.88
PL/J f 3.56 0.54   7 0.204 0.152 2.56, 4.18 -1.02
PL/J m 4.71 0.586   7 0.221 0.124 3.71, 5.53 -0.77
PWD/PhJ f 2.96 0.831   8 0.294 0.281 1.89, 4.4 -1.07
PWD/PhJ m 3.3 0.955   8 0.338 0.289 2.32, 5.23 -0.88
RIIIS/J f 6.76 1.2   8 0.423 0.177 4.8, 8.31 -0.73
RIIIS/J m 8.74 1.44   8 0.509 0.165 7.24, 11.6 -0.45
SJL/J f 6.82 1.33   8 0.472 0.196 5.49, 9.17 -0.73
SJL/J m 14.5 7.0   6 2.86 0.483 7.56, 26.2 0.0
SM/J f 7.86 2.07   16 0.519 0.264 4.84, 11.4 -0.63
SM/J m 7.49 1.16   8 0.411 0.155 6.11, 9.53 -0.55
SWR/J f 42.4 10.9   8 3.85 0.257 27.2, 58.8 2.47
SWR/J m 44.2 4.91   8 1.74 0.111 36.9, 51.6 2.34
WSB/EiJ f 3.12 0.373   8 0.132 0.119 2.59, 3.51 -1.06
WSB/EiJ m 5.18 0.505   6 0.206 0.0973 4.74, 6.12 -0.73


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.8875 2.2333 28.277 19.498
129S1/SvImJ m 29.875 2.2333 34.2645 25.4855
A/J f 22.0 2.2333 26.3895 17.6105
A/J m 25.3375 2.2333 29.727 20.948
AKR/J f 18.5987 2.2333 22.9882 14.2093
AKR/J m 6.5325 2.2333 10.922 2.143
BALB/cByJ f 23.0625 2.2333 27.452 18.673
BALB/cByJ m 5.835 2.2333 10.2245 1.4455
BTBR T+ Itpr3tf/J f 5.3638 2.2333 9.7532 0.9743
BTBR T+ Itpr3tf/J m 6.6637 2.2333 11.0532 2.2743
BUB/BnJ f 17.9287 2.2333 22.3182 13.5393
BUB/BnJ m 19.3625 2.2333 23.752 14.973
C3H/HeJ f 5.135 2.2333 9.5245 0.7455
C3H/HeJ m 6.6975 2.2333 11.087 2.308
C57BL/10J f 10.5062 2.2333 14.8957 6.1168
C57BL/10J m 11.11 2.2333 15.4995 6.7205
C57BL/6J f 16.3875 2.2333 20.777 11.998
C57BL/6J m 6.5563 2.2333 10.9457 2.1668
C57BLKS/J f 10.3575 2.2333 14.747 5.968
C57BLKS/J m 7.1613 2.2333 11.5507 2.7718
C57BR/cdJ f 7.1087 2.2333 11.4982 2.7193
C57BR/cdJ m 10.115 2.2333 14.5045 5.7255
C57L/J f 11.27 2.2333 15.6595 6.8805
C57L/J m 8.1138 2.2333 12.5032 3.7243
CBA/J f 3.5425 2.2333 7.932 0.0
CBA/J m 9.56 2.2333 13.9495 5.1705
DBA/2J f 13.0025 2.2333 17.392 8.613
DBA/2J m 15.025 2.2333 19.4145 10.6355
FVB/NJ f 4.8212 2.2333 9.2107 0.4318
FVB/NJ m 7.2862 2.2333 11.6757 2.8968
KK/HlJ f 36.2125 2.2333 40.602 31.823
KK/HlJ m 8.7562 2.2333 13.1457 4.3668
LP/J f 34.8162 2.2333 39.2057 30.4268
LP/J m 34.6125 2.2333 39.002 30.223
MOLF/EiJ f 14.9857 2.3876 19.6783 10.2931
MOLF/EiJ m 13.825 2.2333 18.2145 9.4355
MRL/MpJ f 18.925 2.2333 23.3145 14.5355
MRL/MpJ m 16.5875 2.2333 20.977 12.198
NOD.B10Sn-H2b/J f 7.6411 2.1056 11.7796 3.5027
NOD.B10Sn-H2b/J m 18.5714 2.3876 23.264 13.8789
NON/ShiLtJ f 21.6375 2.2333 26.027 17.248
NON/ShiLtJ m 59.35 2.2333 63.7395 54.9605
NZO/HlLtJ f 7.575 2.2333 11.9645 3.1855
NZO/HlLtJ m 10.215 2.2333 14.6045 5.8255
NZW/LacJ f 39.425 2.2333 43.8145 35.0355
NZW/LacJ m 20.5375 2.2333 24.927 16.148
P/J f 22.6125 2.2333 27.002 18.223
P/J m 3.3338 2.2333 7.7232 0.0
PL/J f 3.5586 2.3876 8.2511 0.0
PL/J m 4.7114 2.3876 9.404 0.0189
PWD/PhJ f 2.9575 2.2333 7.347 0.0
PWD/PhJ m 3.3037 2.2333 7.6932 0.0
RIIIS/J f 6.7613 2.2333 11.1507 2.3718
RIIIS/J m 8.7388 2.2333 13.1282 4.3493
SJL/J f 6.82 2.2333 11.2095 2.4305
SJL/J m 14.49 2.5788 19.5586 9.4214
SM/J f 7.8563 1.5792 10.9601 4.7524
SM/J m 7.49 2.2333 11.8795 3.1005
SWR/J f 42.375 2.2333 46.7645 37.9855
SWR/J m 44.25 2.2333 48.6395 39.8605
WSB/EiJ f 3.125 2.2333 7.5145 0.0
WSB/EiJ m 5.1833 2.5788 10.2519 0.1148


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.8813 1.5792 29.9851 23.7774
A/J both 23.6687 1.5792 26.7726 20.5649
AKR/J both 12.5656 1.5792 15.6695 9.4618
BALB/cByJ both 14.4488 1.5792 17.5526 11.3449
BTBR T+ Itpr3tf/J both 6.0137 1.5792 9.1176 2.9099
BUB/BnJ both 18.6456 1.5792 21.7495 15.5418
C3H/HeJ both 5.9163 1.5792 9.0201 2.8124
C57BL/10J both 10.8081 1.5792 13.912 7.7043
C57BL/6J both 11.4719 1.5792 14.5757 8.368
C57BLKS/J both 8.7594 1.5792 11.8632 5.6555
C57BR/cdJ both 8.6119 1.5792 11.7157 5.508
C57L/J both 9.6919 1.5792 12.7957 6.588
CBA/J both 6.5512 1.5792 9.6551 3.4474
DBA/2J both 14.0137 1.5792 17.1176 10.9099
FVB/NJ both 6.0537 1.5792 9.1576 2.9499
KK/HlJ both 22.4844 1.5792 25.5882 19.3805
LP/J both 34.7144 1.5792 37.8182 31.6105
MOLF/EiJ both 14.4054 1.6346 17.6181 11.1926
MRL/MpJ both 17.7562 1.5792 20.8601 14.6524
NOD.B10Sn-H2b/J both 13.1063 1.5917 16.2346 9.9779
NON/ShiLtJ both 40.4938 1.5792 43.5976 37.3899
NZO/HlLtJ both 8.895 1.5792 11.9988 5.7912
NZW/LacJ both 29.9813 1.5792 33.0851 26.8774
P/J both 12.9731 1.5792 16.077 9.8693
PL/J both 4.135 1.6883 7.4531 0.8169
PWD/PhJ both 3.1306 1.5792 6.2345 0.0268
RIIIS/J both 7.75 1.5792 10.8538 4.6462
SJL/J both 10.655 1.7057 14.0075 7.3025
SM/J both 7.6731 1.3676 10.3611 4.9851
SWR/J both 43.3125 1.5792 46.4163 40.2087
WSB/EiJ both 4.1542 1.7057 7.5067 0.8016




  GWAS USING LINEAR MIXED MODELS