Project measure / variable:   Petkova1   EOS_M18

ID, description, units MPD:24218   EOS_M18   eosinophil differential (EOS; percentage of total WBC)   [%]  at age 18mo  
Data set, strains Petkova1   inbred   30 strains     sex: both     age: 78wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Petkova1 - eosinophil differential (EOS; percentage of total WBC) at age 18mo



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains25 strains
Mean of the strain means3.15   % 3.85   %
Median of the strain means2.90   % 3.06   %
SD of the strain means± 1.66 ± 2.05
Coefficient of variation (CV)0.527 0.533
Min–max range of strain means0.634   –   9.02   % 1.09   –   8.86   %
Mean sample size per strain7.3   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 11.6239 11.6239 2.0063 0.1578
strain 22 678.557 30.8435 5.3236 < 0.0001
sex:strain 22 214.9262 9.7694 1.6862 0.03
Residuals 278 1610.6678 5.7938


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 9.02 4.81   7 1.82 0.533 1.48, 14.5 3.53
129S1/SvImJ m 6.01 3.03   8 1.07 0.504 3.34, 11.9 1.06
A/J f 1.85 0.744   8 0.263 0.403 0.99, 3.07 -0.78
BALB/cByJ f 3.77 2.25   8 0.796 0.597 0.55, 6.72 0.37
BALB/cByJ m 8.46 4.24   6 1.73 0.501 1.92, 13.7 2.25
BTBR T+ Itpr3tf/J f 2.9 0.904   8 0.319 0.312 1.85, 4.16 -0.15
BTBR T+ Itpr3tf/J m 1.98 0.244   5 0.109 0.123 1.59, 2.21 -0.91
BUB/BnJ f 3.78 1.82   8 0.643 0.481 1.18, 7.27 0.38
BUB/BnJ m 2.79 1.11   6 0.454 0.398 1.26, 4.66 -0.52
C3H/HeJ f 4.13 3.51   8 1.24 0.849 1.72, 12.5 0.59
C3H/HeJ m 3.06 0.907   8 0.321 0.297 2.09, 4.93 -0.38
C57BL/10J f 2.85 1.02   7 0.386 0.358 1.33, 4.23 -0.18
C57BL/10J m 8.86 0.0   1   0.0 0.0 8.86, 8.86 2.45
C57BL/6J f 3.82 3.88   8 1.37 1.01 1.53, 13.1 0.4
C57BL/6J m 3.0 1.26   7 0.477 0.42 1.65, 5.68 -0.41
C57BLKS/J f 5.81 1.6   7 0.606 0.276 3.69, 7.84 1.6
C57BR/cdJ f 3.56 1.17   8 0.412 0.328 1.04, 5.0 0.24
C57BR/cdJ m 3.77 1.16   8 0.411 0.309 2.33, 6.08 -0.04
C57L/J f 2.59 0.545   8 0.193 0.21 1.89, 3.31 -0.34
C57L/J m 2.33 0.566   6 0.231 0.243 1.41, 3.17 -0.74
CBA/J f 2.29 1.09   8 0.384 0.474 1.33, 4.27 -0.52
CBA/J m 1.73 0.473   6 0.193 0.274 1.11, 2.2 -1.03
DBA/2J f 2.16 1.27   7 0.481 0.589 0.85, 4.24 -0.6
DBA/2J m 2.28 1.11   8 0.393 0.488 0.71, 4.03 -0.76
FVB/NJ f 1.85 0.941   8 0.333 0.51 0.91, 3.89 -0.78
KK/HlJ f 1.9 0.75   7 0.284 0.394 0.9, 3.34 -0.75
KK/HlJ m 4.01 1.14   7 0.432 0.285 2.15, 5.7 0.08
LP/J f 3.21 0.957   7 0.362 0.299 2.07, 4.72 0.03
LP/J m 3.87 0.768   8 0.272 0.198 2.93, 4.88 0.01
MOLF/EiJ f 2.0 0.583   9 0.194 0.292 1.04, 2.84 -0.69
MOLF/EiJ m 2.52 0.726   7 0.274 0.288 1.85, 3.54 -0.65
MRL/MpJ f 3.23 1.44   6 0.588 0.447 1.85, 5.8 0.05
MRL/MpJ m 6.67 2.76   8 0.977 0.414 3.72, 11.2 1.38
NOD.B10Sn-H2b/J f 2.33 1.2   7 0.454 0.517 1.15, 4.82 -0.5
NOD.B10Sn-H2b/J m 1.62 0.633   6 0.258 0.39 1.17, 2.87 -1.09
NON/ShiLtJ f 1.89 0.574   7 0.217 0.304 1.32, 2.9 -0.76
NON/ShiLtJ m 2.97 0.768   7 0.29 0.258 1.91, 3.84 -0.43
NZO/HlLtJ f 1.44 1.03   3 0.595 0.714 0.36, 2.41 -1.03
NZW/LacJ f 1.3 1.24   8 0.438 0.955 0.44, 4.11 -1.11
NZW/LacJ m 1.09 0.523   7 0.198 0.48 0.33, 1.8 -1.35
P/J f 1.75 1.25   5 0.559 0.716 0.42, 3.56 -0.84
P/J m 3.75 2.58   4 1.29 0.687 2.33, 7.61 -0.05
PL/J f 4.52 1.9   4 0.949 0.42 2.17, 6.11 0.82
PL/J m 4.47 1.67   5 0.747 0.373 2.11, 6.72 0.3
PWD/PhJ f 4.03 2.28   8 0.806 0.566 1.96, 9.32 0.53
PWD/PhJ m 2.52 0.742   8 0.262 0.294 1.81, 3.78 -0.65
RIIIS/J m 2.56 1.02   8 0.361 0.398 1.51, 4.26 -0.63
SJL/J f 5.19 5.72   8 2.02 1.1 0.38, 17.9 1.22
SJL/J m 6.23 9.04   7 3.42 1.45 0.73, 25.5 1.16
SM/J f 0.634 0.29   7 0.11 0.458 0.39, 1.22 -1.51
SWR/J f 4.33 1.8   7 0.681 0.416 2.43, 7.97 0.71
SWR/J m 4.6 1.6   6 0.655 0.349 2.9, 7.48 0.37
WSB/EiJ f 3.33 1.34   8 0.475 0.403 1.51, 5.66 0.11
WSB/EiJ m 5.01 1.73   7 0.652 0.345 3.07, 8.32 0.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 9.0243 0.9098 10.8152 7.2334
129S1/SvImJ m 6.0062 0.851 7.6815 4.331
BALB/cByJ f 3.77 0.851 5.4452 2.0948
BALB/cByJ m 8.4617 0.9827 10.3961 6.5273
BTBR T+ Itpr3tf/J f 2.9 0.851 4.5752 1.2248
BTBR T+ Itpr3tf/J m 1.982 1.0765 4.101 0.0
BUB/BnJ f 3.7837 0.851 5.459 2.1085
BUB/BnJ m 2.7917 0.9827 4.7261 0.8573
C3H/HeJ f 4.13 0.851 5.8052 2.4548
C3H/HeJ m 3.055 0.851 4.7302 1.3798
C57BL/6J f 3.8225 0.851 5.4977 2.1473
C57BL/6J m 3.0014 0.9098 4.7923 1.2105
C57BR/cdJ f 3.5613 0.851 5.2365 1.886
C57BR/cdJ m 3.765 0.851 5.4402 2.0898
C57L/J f 2.5925 0.851 4.2677 0.9173
C57L/J m 2.3317 0.9827 4.2661 0.3973
CBA/J f 2.29 0.851 3.9652 0.6148
CBA/J m 1.7283 0.9827 3.6627 0.0
DBA/2J f 2.1629 0.9098 3.9538 0.3719
DBA/2J m 2.28 0.851 3.9552 0.6048
KK/HlJ f 1.9043 0.9098 3.6952 0.1134
KK/HlJ m 4.01 0.9098 5.8009 2.2191
LP/J f 3.2057 0.9098 4.9966 1.4148
LP/J m 3.8725 0.851 5.5477 2.1973
MOLF/EiJ f 1.9989 0.8023 3.5783 0.4195
MOLF/EiJ m 2.5229 0.9098 4.3138 0.7319
MRL/MpJ f 3.2267 0.9827 5.1611 1.2923
MRL/MpJ m 6.6737 0.851 8.349 4.9985
NOD.B10Sn-H2b/J f 2.3271 0.9098 4.1181 0.5362
NOD.B10Sn-H2b/J m 1.6233 0.9827 3.5577 0.0
NON/ShiLtJ f 1.8871 0.9098 3.6781 0.0962
NON/ShiLtJ m 2.9743 0.9098 4.7652 1.1834
NZW/LacJ f 1.2963 0.851 2.9715 0.0
NZW/LacJ m 1.09 0.9098 2.8809 0.0
P/J f 1.746 1.0765 3.865 0.0
P/J m 3.7525 1.2035 6.1217 1.3833
PL/J f 4.5175 1.2035 6.8867 2.1483
PL/J m 4.472 1.0765 6.591 2.353
PWD/PhJ f 4.0313 0.851 5.7065 2.356
PWD/PhJ m 2.5238 0.851 4.199 0.8485
SJL/J f 5.1913 0.851 6.8665 3.516
SJL/J m 6.2271 0.9098 8.0181 4.4362
SWR/J f 4.3329 0.9098 6.1238 2.5419
SWR/J m 4.5967 0.9827 6.5311 2.6623
WSB/EiJ f 3.3287 0.851 5.004 1.6535
WSB/EiJ m 5.0071 0.9098 6.7981 3.2162


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.5153 0.6229 8.7414 6.2891
BALB/cByJ both 6.1158 0.65 7.3953 4.8363
BTBR T+ Itpr3tf/J both 2.441 0.6861 3.7916 1.0904
BUB/BnJ both 3.2877 0.65 4.5672 2.0082
C3H/HeJ both 3.5925 0.6018 4.7771 2.4079
C57BL/6J both 3.412 0.6229 4.6381 2.1858
C57BR/cdJ both 3.6631 0.6018 4.8477 2.4785
C57L/J both 2.4621 0.65 3.7416 1.1826
CBA/J both 2.0092 0.65 3.2887 0.7297
DBA/2J both 2.2214 0.6229 3.4476 0.9953
KK/HlJ both 2.9571 0.6433 4.2235 1.6908
LP/J both 3.5391 0.6229 4.7653 2.313
MOLF/EiJ both 2.2609 0.6065 3.4548 1.0669
MRL/MpJ both 4.9502 0.65 6.2297 3.6707
NOD.B10Sn-H2b/J both 1.9752 0.6696 3.2933 0.6572
NON/ShiLtJ both 2.4307 0.6433 3.6971 1.1643
NZW/LacJ both 1.1931 0.6229 2.4193 0.0
P/J both 2.7492 0.8073 4.3385 1.16
PL/J both 4.4948 0.8073 6.084 2.9055
PWD/PhJ both 3.2775 0.6018 4.4621 2.0929
SJL/J both 5.7092 0.6229 6.9354 4.483
SWR/J both 4.4648 0.6696 5.7828 3.1467
WSB/EiJ both 4.1679 0.6229 5.3941 2.9418




  GWAS USING LINEAR MIXED MODELS