Project measure / variable:   Jaxpheno3   HDL16

ID, description, units MPD:22836   HDL16   HDL cholesterol (plasma HDL)   [mg/dL]  at age 16wks  
Data set, strains Jaxpheno3   inbred   8 strains     sex: both     age: 16wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Jaxpheno3 - HDL cholesterol (plasma HDL) at age 16wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means71.9   mg/dL 100   mg/dL
Median of the strain means68.5   mg/dL 98.2   mg/dL
SD of the strain means± 14.0 ± 13.5
Coefficient of variation (CV)0.195 0.135
Min–max range of strain means56.4   –   95.5   mg/dL 79.7   –   125   mg/dL
Mean sample size per strain16.2   mice 16.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 41825.1284 41825.1284 182.4958 < 0.0001
strain 7 38772.3594 5538.9085 24.168 < 0.0001
sex:strain 7 7759.3214 1108.4745 4.8366 < 0.0001
Residuals 245 56150.0874 229.184


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6D2F1/J f 68.4 10.6   10 3.36 0.155 55.0, 85.0 -0.25
B6D2F1/J m 102.0 5.31   10 1.68 0.0519 95.0, 111.0 0.12
BALB/cByJ f 67.9 6.84   20 1.53 0.101 56.0, 81.0 -0.29
BALB/cByJ m 112.0 11.2   20 2.49 0.0991 88.0, 127.0 0.86
C3H/HeJ f 95.5 7.66   10 2.42 0.0802 81.5, 106.0 1.69
C3H/HeJ m 125.0 17.1   10 5.41 0.137 92.4, 145.0 1.82
C57BL/6J f 58.6 4.25   30 0.777 0.0726 50.0, 68.0 -0.95
C57BL/6J m 79.7 8.12   30 1.48 0.102 68.0, 103.0 -1.53
CBA/J f 69.2 4.37   10 1.38 0.0631 61.0, 75.0 -0.19
CBA/J m 94.5 13.7   20 3.07 0.145 76.0, 117.0 -0.43
DBA/2J f 56.4 7.07   10 2.24 0.125 49.0, 73.0 -1.11
DBA/2J m 93.1 2.96   10 0.936 0.0318 89.0, 99.0 -0.54
NOD.CB17-Prkdcscid/J f 68.6 4.09   10 1.29 0.0596 61.0, 76.0 -0.24
NOD.CB17-Prkdcscid/J m 95.5 10.5   10 3.31 0.11 70.0, 110.0 -0.36
NOD/ShiLtJ f 90.6 36.3   30 6.62 0.401 45.0, 176.0 1.34
NOD/ShiLtJ m 101.0 11.1   21 2.42 0.11 84.0, 127.0 0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 68.4 4.7873 77.8295 58.9705
B6D2F1/J m 102.2 4.7873 111.6295 92.7705
BALB/cByJ f 67.9 3.3851 74.5677 61.2323
BALB/cByJ m 112.5 3.3851 119.1677 105.8323
C3H/HeJ f 95.53 4.7873 104.9595 86.1005
C3H/HeJ m 124.54 4.7873 133.9695 115.1105
C57BL/6J f 58.6333 2.764 64.0775 53.1892
C57BL/6J m 79.6667 2.764 85.1108 74.2225
CBA/J f 69.2 4.7873 78.6295 59.7705
CBA/J m 94.55 3.3851 101.2177 87.8823
DBA/2J f 56.4 4.7873 65.8295 46.9705
DBA/2J m 93.1 4.7873 102.5295 83.6705
NOD.CB17-Prkdcscid/J f 68.6 4.7873 78.0295 59.1705
NOD.CB17-Prkdcscid/J m 95.5 4.7873 104.9295 86.0705
NOD/ShiLtJ f 90.5667 2.764 96.0108 85.1225
NOD/ShiLtJ m 100.9524 3.3036 107.4594 94.4454


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 85.3 3.3851 91.9677 78.6323
BALB/cByJ both 90.2 2.3937 94.9148 85.4852
C3H/HeJ both 110.035 3.3851 116.7027 103.3673
C57BL/6J both 69.15 1.9544 72.9996 65.3004
CBA/J both 81.875 2.9316 87.6494 76.1006
DBA/2J both 74.75 3.3851 81.4177 68.0823
NOD.CB17-Prkdcscid/J both 82.05 3.3851 88.7177 75.3823
NOD/ShiLtJ both 95.7595 2.1537 100.0016 91.5175




  GWAS USING LINEAR MIXED MODELS