Project measure / variable:   Jaxpheno3   HDL8

ID, description, units MPD:22835   HDL8   HDL cholesterol (plasma HDL)   [mg/dL]  at age 8wks  
Data set, strains Jaxpheno3   inbred   11 strains     sex: both     age: 8wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Jaxpheno3 - HDL cholesterol (plasma HDL) at age 8wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested11 strains11 strains
Mean of the strain means85.9   mg/dL 114   mg/dL
Median of the strain means69.9   mg/dL 99.6   mg/dL
SD of the strain means± 37.5 ± 44.3
Coefficient of variation (CV)0.437 0.388
Min–max range of strain means62.3   –   190   mg/dL 76.5   –   236   mg/dL
Mean sample size per strain15.8   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 60151.3952 60151.3952 660.0523 < 0.0001
strain 10 377905.8737 37790.5874 414.6831 < 0.0001
sex:strain 10 8155.5545 815.5554 8.9492 < 0.0001
Residuals 378 34447.6141 91.1313


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6.129P2-Apoetm1Unc/J f 190.0 22.6   10 7.14 0.119 156.0, 219.0 2.77
B6.129P2-Apoetm1Unc/J m 236.0 28.2   10 8.91 0.119 206.0, 286.0 2.75
B6D2F1/J f 67.0 6.68   10 2.11 0.0998 55.0, 76.0 -0.5
B6D2F1/J m 108.0 6.73   10 2.13 0.0622 96.0, 118.0 -0.14
BALB/cByJ f 74.2 6.12   20 1.37 0.0826 60.0, 84.0 -0.31
BALB/cByJ m 101.0 8.66   20 1.94 0.0861 80.0, 114.0 -0.3
BALB/cJ f 69.0 7.6   20 1.7 0.11 53.0, 84.0 -0.45
BALB/cJ m 76.5 7.4   22 1.58 0.0969 63.0, 89.0 -0.85
C3H/HeJ f 104.0 4.6   10 1.45 0.0444 95.0, 109.0 0.48
C3H/HeJ m 126.0 7.35   10 2.32 0.0585 116.0, 142.0 0.27
C57BL/6J f 67.3 7.95   30 1.45 0.118 52.0, 80.0 -0.5
C57BL/6J m 89.9 10.9   54 1.49 0.122 61.0, 119.0 -0.55
CBA/J f 69.9 6.36   21 1.39 0.0909 61.0, 81.0 -0.43
CBA/J m 99.6 8.18   30 1.49 0.0821 81.0, 115.0 -0.33
DBA/2J f 62.3 7.79   21 1.7 0.125 50.0, 81.0 -0.63
DBA/2J m 90.8 8.63   20 1.93 0.0951 77.0, 113.0 -0.53
FVB/NJ f 105.0 7.65   10 2.42 0.0728 94.0, 117.0 0.51
FVB/NJ m 142.0 9.36   12 2.7 0.0659 127.0, 156.0 0.63
NOD.CB17-Prkdcscid/J f 66.4 5.23   10 1.65 0.0788 57.0, 73.0 -0.52
NOD.CB17-Prkdcscid/J m 90.2 5.37   10 1.7 0.0595 80.0, 98.0 -0.54
NOD/ShiLtJ f 70.3 5.07   20 1.13 0.0721 58.0, 82.0 -0.42
NOD/ShiLtJ m 96.5 6.52   20 1.46 0.0676 86.0, 111.0 -0.4


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J f 189.5 3.0188 195.4357 183.5643
B6.129P2-Apoetm1Unc/J m 236.5 3.0188 242.4357 230.5643
B6D2F1/J f 67.0 3.0188 72.9357 61.0643
B6D2F1/J m 108.3 3.0188 114.2357 102.3643
BALB/cByJ f 74.15 2.1346 78.3472 69.9528
BALB/cByJ m 100.6 2.1346 104.7972 96.4028
BALB/cJ f 69.0 2.1346 73.1972 64.8028
BALB/cJ m 76.4545 2.0353 80.4564 72.4527
C3H/HeJ f 103.6 3.0188 109.5357 97.6643
C3H/HeJ m 125.7 3.0188 131.6357 119.7643
C57BL/6J f 67.2667 1.7429 70.6937 63.8397
C57BL/6J m 89.9444 1.2991 92.4988 87.3901
CBA/J f 69.9048 2.0832 74.0008 65.8087
CBA/J m 99.6333 1.7429 103.0603 96.2063
DBA/2J f 62.3333 2.0832 66.4294 58.2373
DBA/2J m 90.75 2.1346 94.9472 86.5528
FVB/NJ f 105.1 3.0188 111.0357 99.1643
FVB/NJ m 141.9167 2.7558 147.3352 136.4981
NOD.CB17-Prkdcscid/J f 66.4 3.0188 72.3357 60.4643
NOD.CB17-Prkdcscid/J m 90.2 3.0188 96.1357 84.2643
NOD/ShiLtJ f 70.35 2.1346 74.5472 66.1528
NOD/ShiLtJ m 96.45 2.1346 100.6472 92.2528


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6.129P2-Apoetm1Unc/J both 213.0 2.1346 217.1972 208.8028
B6D2F1/J both 87.65 2.1346 91.8472 83.4528
BALB/cByJ both 87.375 1.5094 90.3429 84.4071
BALB/cJ both 72.7273 1.4747 75.6269 69.8276
C3H/HeJ both 114.65 2.1346 118.8472 110.4528
C57BL/6J both 78.6056 1.0869 80.7427 76.4684
CBA/J both 84.769 1.3581 87.4393 82.0988
DBA/2J both 76.5417 1.4913 79.474 73.6093
FVB/NJ both 123.5083 2.0437 127.5268 119.4898
NOD.CB17-Prkdcscid/J both 78.3 2.1346 82.4972 74.1028
NOD/ShiLtJ both 83.4 1.5094 86.3679 80.4321




  GWAS USING LINEAR MIXED MODELS