Project measure / variable:   Crabbe5   err_EtOH_D3

ID, description, units MPD:19606   err_EtOH_D3   motor incoordination, errors over distance traveled, 1.6mm rod, 6mm space   [n/cm]  day3 ethanol  
ethanol study
Data set, strains Crabbe5   inbred   8 strains     sex: both     age: 7-14wks
Procedure parallel rod floor test
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe5 - motor incoordination, errors over distance traveled, 1.6mm rod, 6mm space day3 ethanol



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains8 strains
Mean of the strain means27.9   n/cm 27.7   n/cm
Median of the strain means26.8   n/cm 22.8   n/cm
SD of the strain means± 9.51 ± 9.59
Coefficient of variation (CV)0.341 0.346
Min–max range of strain means16.9   –   41.4   n/cm 18.1   –   39.6   n/cm
Mean sample size per strain5.6   mice 5.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.8868 9.8868 0.0436 0.8352
strain 6 4276.6291 712.7715 3.1453 0.0091
sex:strain 6 2313.2884 385.5481 1.7013 0.1351
Residuals 64 14503.4286 226.6161


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 39.9 12.7   6 5.2 0.32 26.9, 59.3 1.26
129S1/SvImJ m 38.7 37.4   6 15.3 0.967 10.8, 112.0 1.14
A/J f 28.3 8.25   6 3.37 0.291 16.8, 42.5 0.04
A/J m 39.6 13.6   6 5.54 0.343 23.4, 58.1 1.24
BALB/cByJ f 21.6 4.02   3 2.32 0.186 17.8, 25.8 -0.66
BALB/cByJ m 18.1 6.73   6 2.75 0.372 11.0, 27.0 -1.0
BTBR T+ Itpr3tf/J f 20.5 6.55   6 2.67 0.319 14.7, 32.6 -0.78
BTBR T+ Itpr3tf/J m 24.0 6.93   5 3.1 0.289 15.9, 34.4 -0.39
C3H/HeJ f 26.8 6.7   6 2.74 0.25 19.3, 33.5 -0.12
C3H/HeJ m 39.1 21.2   6 8.65 0.542 14.0, 71.9 1.19
C57BL/6J f 41.4 18.4   6 7.51 0.444 13.7, 64.2 1.42
C57BL/6J m 19.9 8.0   6 3.27 0.403 6.77, 27.8 -0.82
DBA/2J f 16.9 5.33   6 2.18 0.316 11.5, 23.6 -1.16
DBA/2J m 20.8 6.9   4 3.45 0.332 13.9, 30.2 -0.72
FVB/NJ m 21.6 9.24   6 3.77 0.427 12.6, 36.8 -0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 39.8667 6.1457 52.1441 27.5893
129S1/SvImJ m 38.6667 6.1457 50.9441 26.3893
A/J f 28.3333 6.1457 40.6107 16.0559
A/J m 39.6167 6.1457 51.8941 27.3393
BALB/cByJ f 21.5667 8.6913 38.9295 4.2038
BALB/cByJ m 18.0667 6.1457 30.3441 5.7893
BTBR T+ Itpr3tf/J f 20.5167 6.1457 32.7941 8.2393
BTBR T+ Itpr3tf/J m 24.02 6.7323 37.4692 10.5708
C3H/HeJ f 26.8167 6.1457 39.0941 14.5393
C3H/HeJ m 39.1167 6.1457 51.3941 26.8393
C57BL/6J f 41.3833 6.1457 53.6607 29.1059
C57BL/6J m 19.8617 6.1457 32.1391 7.5843
DBA/2J f 16.8667 6.1457 29.1441 4.5893
DBA/2J m 20.775 7.5269 35.8117 5.7383


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 39.2667 4.3456 47.9481 30.5852
A/J both 33.975 4.3456 42.6564 25.2936
BALB/cByJ both 19.8167 5.3223 30.4492 9.1841
BTBR T+ Itpr3tf/J both 22.2683 4.5578 31.3735 13.1632
C3H/HeJ both 32.9667 4.3456 41.6481 24.2852
C57BL/6J both 30.6225 4.3456 39.3039 21.9411
DBA/2J both 18.8208 4.8586 28.527 9.1147




  GWAS USING LINEAR MIXED MODELS