Project measure / variable:   Cheverud1   CHOL_hifat

ID, description, units MPD:17892   CHOL_hifat   total cholesterol (serum CHOL)   [mg/dL]  high-fat diet  
high-fat diet study
Data set, strains Cheverud1   LGXSM w/par   17 strains     sex: both     age: 20-30wks
Procedure lipid profile
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  STRAIN COMPARISON PLOT
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Cheverud1 - total cholesterol (serum CHOL) high-fat diet



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested13 strains17 strains
Mean of the strain means177   mg/dL 187   mg/dL
Median of the strain means163   mg/dL 183   mg/dL
SD of the strain means± 62.6 ± 40.0
Coefficient of variation (CV)0.353 0.214
Min–max range of strain means95.1   –   328   mg/dL 146   –   294   mg/dL
Mean sample size per strain8.1   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 29.6758 29.6758 0.0119 0.9132
strain 12 573455.5492 47787.9624 19.1882 < 0.0001
sex:strain 12 77809.4314 6484.1193 2.6036 0.0031
Residuals 192 478173.8819 2490.489


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
LGXSM10 f 163.0 47.8   9 15.9 0.293 105.0, 245.0 -0.23
LGXSM10 m 149.0 27.1   10 8.59 0.182 106.0, 206.0 -0.94
LGXSM15 f 171.0 37.4   9 12.5 0.219 130.0, 246.0 -0.1
LGXSM15 m 156.0 43.2   11 13.0 0.277 81.8, 232.0 -0.76
LGXSM18 f 113.0 37.2   9 12.4 0.328 44.8, 159.0 -1.02
LGXSM18 m 146.0 30.5   8 10.8 0.208 115.0, 200.0 -1.01
LGXSM19 f 155.0 25.9   9 8.63 0.167 110.0, 191.0 -0.35
LGXSM19 m 163.0 20.1   8 7.1 0.123 141.0, 196.0 -0.59
LGXSM20 f 146.0 27.0   5 12.1 0.185 103.0, 177.0 -0.5
LGXSM20 m 183.0 44.0   6 18.0 0.241 112.0, 234.0 -0.09
LGXSM22 f 328.0 66.9   13 18.6 0.204 168.0, 400.0 2.41
LGXSM22 m 294.0 76.1   12 22.0 0.259 194.0, 436.0 2.69
LGXSM23 f 239.0 78.6   8 27.8 0.329 161.0, 391.0 0.99
LGXSM23 m 169.0 52.4   10 16.6 0.31 88.6, 237.0 -0.44
LGXSM31 m 202.0 89.1   4 44.5 0.441 70.3, 261.0 0.39
LGXSM33 f 130.0 41.6   10 13.2 0.32 83.4, 188.0 -0.75
LGXSM33 m 196.0 94.5   13 26.2 0.483 77.6, 379.0 0.24
LGXSM38 f 144.0 41.4   7 15.7 0.288 97.2, 198.0 -0.53
LGXSM38 m 148.0 21.9   7 8.28 0.148 122.0, 190.0 -0.96
LGXSM39 m 160.0 11.3   3 6.51 0.0704 153.0, 173.0 -0.66
LGXSM4 f 243.0 36.8   7 13.9 0.151 191.0, 292.0 1.05
LGXSM4 m 198.0 41.6   6 17.0 0.211 143.0, 249.0 0.29
LGXSM45 f 95.1 13.7   3 7.88 0.144 80.8, 108.0 -1.31
LGXSM45 m 153.0 39.0   3 22.5 0.255 111.0, 188.0 -0.84
LGXSM46 f 189.0 39.9   8 14.1 0.212 133.0, 238.0 0.19
LGXSM46 m 206.0 40.8   10 12.9 0.198 153.0, 266.0 0.49
LGXSM48 m 256.0 64.2   8 22.7 0.251 150.0, 327.0 1.74
LGXSM5 f 186.0 20.4   8 7.2 0.109 152.0, 220.0 0.14
LGXSM5 m 195.0 42.4   9 14.1 0.217 124.0, 248.0 0.21
SM/J m 197.0 21.6   6 8.82 0.11 163.0, 226.0 0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 f 163.0 16.6349 195.8107 130.1893
LGXSM10 m 149.0 15.7813 180.1269 117.8731
LGXSM15 f 170.6667 16.6349 203.4774 137.856
LGXSM15 m 155.9818 15.0469 185.6602 126.3034
LGXSM18 f 113.3222 16.6349 146.1329 80.5115
LGXSM18 m 146.125 17.644 180.926 111.324
LGXSM19 f 155.1111 16.6349 187.9218 122.3004
LGXSM19 m 163.125 17.644 197.926 128.324
LGXSM20 f 146.0 22.3181 190.0202 101.9798
LGXSM20 m 182.8333 20.3735 223.018 142.6486
LGXSM22 f 328.4615 13.8411 355.7617 301.1614
LGXSM22 m 293.5833 14.4063 321.9982 265.1684
LGXSM23 f 239.0 17.644 273.801 204.199
LGXSM23 m 169.16 15.7813 200.2869 138.0331
LGXSM33 f 129.9 15.7813 161.0269 98.7731
LGXSM33 m 195.7385 13.8411 223.0386 168.4383
LGXSM38 f 143.7429 18.8622 180.9467 106.539
LGXSM38 m 148.4286 18.8622 185.6324 111.2248
LGXSM4 f 243.2857 18.8622 280.4895 206.0819
LGXSM4 m 197.5 20.3735 237.6847 157.3153
LGXSM45 f 95.1 28.8125 151.9298 38.2702
LGXSM45 m 153.0 28.8125 209.8298 96.1702
LGXSM46 f 188.75 17.644 223.551 153.949
LGXSM46 m 206.2 15.7813 237.3269 175.0731
LGXSM5 f 186.0 17.644 220.801 151.199
LGXSM5 m 194.7778 16.6349 227.5885 161.9671


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
LGXSM10 both 156.0 11.4648 178.6132 133.3868
LGXSM15 both 163.3242 11.2153 185.4452 141.2033
LGXSM18 both 129.7236 12.1247 153.6383 105.8089
LGXSM19 both 159.1181 12.1247 183.0327 135.2034
LGXSM20 both 164.4167 15.1094 194.2184 134.6149
LGXSM22 both 311.0224 9.989 330.7246 291.3203
LGXSM23 both 204.08 11.836 227.4252 180.7348
LGXSM33 both 162.8192 10.4955 183.5206 142.1179
LGXSM38 both 146.0857 13.3376 172.3928 119.7786
LGXSM4 both 220.3929 13.8822 247.7741 193.0116
LGXSM45 both 124.05 20.3735 164.2347 83.8653
LGXSM46 both 197.475 11.836 220.8202 174.1298
LGXSM5 both 190.3889 12.1247 214.3036 166.4742




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA