Project measure / variable:   Donahue2   femur_out

ID, description, units MPD:17220   femur_out   periosteal (outer) circumference, femoral mid-diaphysis   [mm]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure computed tomography
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  STRAIN COMPARISON PLOT
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Donahue2 - periosteal (outer) circumference, femoral mid-diaphysis



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means4.60   mm 4.90   mm
Median of the strain means4.67   mm 5.02   mm
SD of the strain means± 0.295 ± 0.443
Coefficient of variation (CV)0.0641 0.0904
Min–max range of strain means4.00   –   4.96   mm 3.94   –   5.63   mm
Mean sample size per strain9.8   mice 10.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5.6067 5.6067 254.6217 < 0.0001
strain 9 25.1418 2.7935 126.8662 < 0.0001
sex:strain 9 1.8576 0.2064 9.3735 < 0.0001
Residuals 187 4.1177 0.022


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4.61 0.165   10 0.052 0.0357 4.33, 4.8 0.04
129S1/SvImJ m 4.74 0.168   13 0.0466 0.0355 4.45, 5.02 -0.37
BALB/cJ f 4.76 0.121   10 0.0381 0.0254 4.54, 4.9 0.55
BALB/cJ m 5.04 0.181   10 0.0572 0.0359 4.71, 5.3 0.31
C3H/HeJ f 4.55 0.0834   9 0.0278 0.0183 4.39, 4.66 -0.16
C3H/HeJ m 5.05 0.0987   11 0.0298 0.0195 4.93, 5.25 0.33
C57BL/6J f 4.96 0.118   9 0.0393 0.0238 4.81, 5.16 1.23
C57BL/6J m 5.63 0.274   12 0.0791 0.0487 5.13, 6.06 1.64
C58/J f 4.72 0.153   9 0.0509 0.0324 4.46, 4.95 0.42
C58/J m 4.97 0.211   10 0.0668 0.0425 4.71, 5.36 0.15
FVB/NJ f 4.83 0.156   11 0.0471 0.0323 4.6, 5.11 0.79
FVB/NJ m 5.13 0.0578   9 0.0193 0.0113 5.04, 5.22 0.51
NZB/BlNJ f 4.62 0.0854   11 0.0258 0.0185 4.47, 4.83 0.08
NZB/BlNJ m 5.0 0.136   13 0.0376 0.0272 4.77, 5.2 0.22
PWK/PhJ f 4.0 0.0928   12 0.0268 0.0232 3.85, 4.15 -2.03
PWK/PhJ m 3.94 0.198   10 0.0628 0.0504 3.63, 4.14 -2.17
SJL/J f 4.74 0.101   8 0.0358 0.0213 4.59, 4.92 0.49
SJL/J m 5.03 0.14   11 0.0422 0.0279 4.79, 5.24 0.29
SWR/J f 4.18 0.093   9 0.031 0.0223 4.04, 4.32 -1.42
SWR/J m 4.5 0.0938   10 0.0297 0.0208 4.35, 4.68 -0.91


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4.608 0.0469 4.7006 4.5154
129S1/SvImJ m 4.7369 0.0412 4.8181 4.6557
BALB/cJ f 4.756 0.0469 4.8486 4.6634
BALB/cJ m 5.039 0.0469 5.1316 4.9464
C3H/HeJ f 4.5544 0.0495 4.652 4.4569
C3H/HeJ m 5.05 0.0447 5.1383 4.9617
C57BL/6J f 4.9556 0.0495 5.0531 4.858
C57BL/6J m 5.6275 0.0428 5.712 5.543
C58/J f 4.7211 0.0495 4.8187 4.6235
C58/J m 4.975 0.0469 5.0676 4.8824
FVB/NJ f 4.8345 0.0447 4.9228 4.7463
FVB/NJ m 5.1311 0.0495 5.2287 5.0335
NZB/BlNJ f 4.62 0.0447 4.7083 4.5317
NZB/BlNJ m 4.9969 0.0412 5.0781 4.9157
PWK/PhJ f 4.0033 0.0428 4.0878 3.9188
PWK/PhJ m 3.935 0.0469 4.0276 3.8424
SJL/J f 4.7437 0.0525 4.8472 4.6403
SJL/J m 5.0291 0.0447 5.1174 4.9408
SWR/J f 4.1767 0.0495 4.2742 4.0791
SWR/J m 4.505 0.0469 4.5976 4.4124


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4.6725 0.0312 4.734 4.6109
BALB/cJ both 4.8975 0.0332 4.963 4.832
C3H/HeJ both 4.8022 0.0333 4.868 4.7364
C57BL/6J both 5.2915 0.0327 5.3561 5.227
C58/J both 4.8481 0.0341 4.9153 4.7808
FVB/NJ both 4.9828 0.0333 5.0486 4.917
NZB/BlNJ both 4.8085 0.0304 4.8684 4.7485
PWK/PhJ both 3.9692 0.0318 4.0318 3.9065
SJL/J both 4.8864 0.0345 4.9544 4.8184
SWR/J both 4.3408 0.0341 4.4081 4.2736




  GWAS USING LINEAR MIXED MODELS