Project measure / variable:   Donahue2   femur_thickness_R2

ID, description, units MPD:17218   femur_thickness_R2   cortical thickness of right femur, µCT   [mm]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure computed tomography
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  STRAIN COMPARISON PLOT
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Donahue2 - cortical thickness of right femur, µCT



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means0.245   mm 0.255   mm
Median of the strain means0.236   mm 0.238   mm
SD of the strain means± 0.0472 ± 0.0507
Coefficient of variation (CV)0.192 0.199
Min–max range of strain means0.203   –   0.365   mm 0.208   –   0.378   mm
Mean sample size per strain9.9   mice 11.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0085 0.0085 54.5925 < 0.0001
strain 9 0.4331 0.0481 309.2124 < 0.0001
sex:strain 9 0.0061 0.0007 4.3789 < 0.0001
Residuals 190 0.0296 0.0002


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.24 0.0076   10 0.0024 0.0317 0.224, 0.252 -0.11
129S1/SvImJ m 0.258 0.021   14 0.00562 0.0815 0.227, 0.296 0.06
BALB/cJ f 0.267 0.00721   10 0.00228 0.0271 0.252, 0.275 0.46
BALB/cJ m 0.283 0.0142   10 0.00449 0.0501 0.266, 0.311 0.55
C3H/HeJ f 0.365 0.0163   9 0.00545 0.0447 0.335, 0.386 2.54
C3H/HeJ m 0.378 0.0099   11 0.00299 0.0262 0.362, 0.392 2.42
C57BL/6J f 0.203 0.00619   10 0.00196 0.0305 0.193, 0.215 -0.89
C57BL/6J m 0.221 0.0114   12 0.00329 0.0516 0.205, 0.24 -0.67
C58/J f 0.225 0.00937   10 0.00296 0.0417 0.206, 0.235 -0.43
C58/J m 0.228 0.00968   10 0.00306 0.0424 0.216, 0.246 -0.53
FVB/NJ f 0.233 0.00458   10 0.00145 0.0197 0.228, 0.24 -0.26
FVB/NJ m 0.219 0.011   9 0.00368 0.0503 0.21, 0.246 -0.71
NZB/BlNJ f 0.259 0.0171   11 0.00515 0.066 0.231, 0.288 0.29
NZB/BlNJ m 0.284 0.0169   13 0.00468 0.0594 0.256, 0.304 0.57
PWK/PhJ f 0.209 0.0117   12 0.00338 0.0562 0.183, 0.225 -0.77
PWK/PhJ m 0.208 0.0153   11 0.00461 0.0736 0.184, 0.237 -0.93
SJL/J f 0.241 0.0128   8 0.00453 0.0532 0.224, 0.269 -0.09
SJL/J m 0.248 0.00631   11 0.0019 0.0254 0.238, 0.257 -0.14
SWR/J f 0.209 0.00889   9 0.00296 0.0425 0.195, 0.22 -0.77
SWR/J m 0.224 0.0104   10 0.00328 0.0464 0.212, 0.243 -0.61


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2396 0.0039 0.2474 0.2318
129S1/SvImJ m 0.258 0.0033 0.2646 0.2514
BALB/cJ f 0.2665 0.0039 0.2743 0.2587
BALB/cJ m 0.2835 0.0039 0.2913 0.2757
C3H/HeJ f 0.3651 0.0042 0.3733 0.3569
C3H/HeJ m 0.3775 0.0038 0.385 0.3701
C57BL/6J f 0.2026 0.0039 0.2104 0.1948
C57BL/6J m 0.221 0.0036 0.2281 0.2139
C58/J f 0.2247 0.0039 0.2325 0.2169
C58/J m 0.2281 0.0039 0.2359 0.2203
FVB/NJ f 0.2331 0.0039 0.2409 0.2253
FVB/NJ m 0.2192 0.0042 0.2274 0.211
NZB/BlNJ f 0.2587 0.0038 0.2661 0.2513
NZB/BlNJ m 0.2839 0.0035 0.2907 0.2771
PWK/PhJ f 0.2086 0.0036 0.2157 0.2015
PWK/PhJ m 0.208 0.0038 0.2154 0.2006
SJL/J f 0.2413 0.0044 0.2499 0.2326
SJL/J m 0.248 0.0038 0.2554 0.2406
SWR/J f 0.2091 0.0042 0.2173 0.2009
SWR/J m 0.2236 0.0039 0.2314 0.2158


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2488 0.0026 0.2539 0.2437
BALB/cJ both 0.275 0.0028 0.2805 0.2695
C3H/HeJ both 0.3713 0.0028 0.3769 0.3658
C57BL/6J both 0.2118 0.0027 0.2171 0.2065
C58/J both 0.2264 0.0028 0.2319 0.2209
FVB/NJ both 0.2262 0.0029 0.2318 0.2205
NZB/BlNJ both 0.2713 0.0026 0.2764 0.2663
PWK/PhJ both 0.2083 0.0026 0.2134 0.2032
SJL/J both 0.2446 0.0029 0.2503 0.2389
SWR/J both 0.2164 0.0029 0.222 0.2107




  GWAS USING LINEAR MIXED MODELS