Project measure / variable:   Metten1   wobble_doseB_30min


  STRAIN COMPARISON PLOT
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Metten1 - erratic gait, 3.0 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.357   score 0.386   score
Median of the strain means0.250   score 0.250   score
SD of the strain means± 0.331 ± 0.343
Coefficient of variation (CV)0.927 0.888
Min–max range of strain means0   –   1.00   score 0   –   1.00   score
Mean sample size per strain4.6   mice 3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0064 0.0064 0.0343 0.8538
strain 8 5.7709 0.7214 3.8705 0.001
sex:strain 8 0.6258 0.0782 0.4197 0.9048
Residuals 61 11.369 0.1864


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 0.333 0.577   3 0.333 1.73 -0.07
129P3/J m 0.667 0.577   3 0.333 0.866 0.82
129S1/SvImJ f 0.0 0.0   4 0.0 0.0 -1.08
129S1/SvImJ m 0.0 0.0   4 0.0 0.0 -1.13
A/J f 0.25 0.5   4 0.25 2.0 -0.32
A/J m 0.25 0.5   4 0.25 2.0 -0.4
BALB/cByJ f 0.167 0.408   6 0.167 2.45 -0.57
BALB/cByJ m 0.143 0.378   7 0.143 2.65 -0.71
BTBR T+ Itpr3tf/J f 0.0 0.0   4 0.0 0.0 -1.08
BTBR T+ Itpr3tf/J m 0.25 0.5   4 0.25 2.0 -0.4
C3H/HeJ f 0.5 0.577   4 0.289 1.15 0.43
C3H/HeJ m 0.667 0.577   3 0.333 0.866 0.82
C57BL/6J f 0.714 0.488   7 0.184 0.683 1.08
C57BL/6J m 0.5 0.548   6 0.224 1.1 0.33
DBA/2J f 0.25 0.463   8 0.164 1.85 -0.32
DBA/2J m 0.0 0.0   3 0.0 0.0 -1.13
FVB/NJ f 1.0 0.0   2   0.0 0.0 1.0, 1.0 1.94
FVB/NJ m 1.0 0.0   3 0.0 0.0 1.0, 1.0 1.79


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 0.3333 0.2493 0.8317 -0.1651
129P3/J m 0.6667 0.2493 1.1651 0.1683
129S1/SvImJ f 0.0 0.2159 0.4316 -0.4316
129S1/SvImJ m 0.0 0.2159 0.4316 -0.4316
A/J f 0.25 0.2159 0.6816 -0.1816
A/J m 0.25 0.2159 0.6816 -0.1816
BALB/cByJ f 0.1667 0.1762 0.5191 -0.1858
BALB/cByJ m 0.1429 0.1632 0.4691 -0.1834
BTBR T+ Itpr3tf/J f 0.0 0.2159 0.4316 -0.4316
BTBR T+ Itpr3tf/J m 0.25 0.2159 0.6816 -0.1816
C3H/HeJ f 0.5 0.2159 0.9316 0.0684
C3H/HeJ m 0.6667 0.2493 1.1651 0.1683
C57BL/6J f 0.7143 0.1632 1.0406 0.388
C57BL/6J m 0.5 0.1762 0.8524 0.1476
DBA/2J f 0.25 0.1526 0.5552 -0.0552
DBA/2J m 0.0 0.2493 0.4984 -0.4984
FVB/NJ f 1.0 0.3053 1.6104 0.3896
FVB/NJ m 1.0 0.2493 1.4984 0.5016


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 0.5 0.1762 0.8524 0.1476
129S1/SvImJ both 0.0 0.1526 0.3052 -0.3052
A/J both 0.25 0.1526 0.5552 -0.0552
BALB/cByJ both 0.1548 0.1201 0.3949 -0.0854
BTBR T+ Itpr3tf/J both 0.125 0.1526 0.4302 -0.1802
C3H/HeJ both 0.5833 0.1649 0.913 0.2537
C57BL/6J both 0.6071 0.1201 0.8473 0.367
DBA/2J both 0.125 0.1461 0.4172 -0.1672
FVB/NJ both 1.0 0.1971 1.394 0.606




GWAS analysis not available: At least 12 strains are required