Project measure / variable:   Metten1   wobble_doseA_30min


  STRAIN COMPARISON PLOT
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Metten1 - erratic gait, 2.75 g/kg i.p. 30min after



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.501   score 0.428   score
Median of the strain means0.333   score 0.333   score
SD of the strain means± 0.343 ± 0.461
Coefficient of variation (CV)0.685 1.08
Min–max range of strain means0.167   –   1.00   score 0   –   1.33   score
Mean sample size per strain4.4   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0322 0.0322 0.1136 0.7373
strain 8 9.3717 1.1715 4.1255 0.0006
sex:strain 8 0.9455 0.1182 0.4162 0.9069
Residuals 61 17.3214 0.284


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 1.0 1.0   3 0.577 1.0 1.45
129P3/J m 1.33 1.53   3 0.882 1.15 1.96
129S1/SvImJ f 0.25 0.5   4 0.25 2.0 -0.73
129S1/SvImJ m 0.0 0.0   4 0.0 0.0 -0.93
A/J f 0.333 0.577   3 0.333 1.73 -0.49
A/J m 0.25 0.5   4 0.25 2.0 -0.39
BALB/cByJ f 0.167 0.408   6 0.167 2.45 -0.97
BALB/cByJ m 0.333 0.516   6 0.211 1.55 -0.21
BTBR T+ Itpr3tf/J f 0.25 0.5   4 0.25 2.0 -0.73
BTBR T+ Itpr3tf/J m 0.0 0.0   4 0.0 0.0 -0.93
C3H/HeJ f 1.0 0.0   4 0.0 0.0 1.0, 1.0 1.45
C3H/HeJ m 0.75 0.5   4 0.25 0.667 0.7
C57BL/6J f 0.833 0.408   6 0.167 0.49 0.97
C57BL/6J m 0.857 0.378   7 0.143 0.441 0.93
DBA/2J f 0.429 0.535   7 0.202 1.25 -0.21
DBA/2J m 0.0 0.0   3 0.0 0.0 -0.93
FVB/NJ f 0.25 0.5   4 0.25 2.0 -0.73
FVB/NJ m 0.333 0.577   3 0.333 1.73 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 1.0 0.3077 1.6152 0.3848
129P3/J m 1.3333 0.3077 1.9485 0.7181
129S1/SvImJ f 0.25 0.2664 0.7828 -0.2828
129S1/SvImJ m 0.0 0.2664 0.5328 -0.5328
A/J f 0.3333 0.3077 0.9485 -0.2819
A/J m 0.25 0.2664 0.7828 -0.2828
BALB/cByJ f 0.1667 0.2175 0.6017 -0.2683
BALB/cByJ m 0.3333 0.2175 0.7683 -0.1017
BTBR T+ Itpr3tf/J f 0.25 0.2664 0.7828 -0.2828
BTBR T+ Itpr3tf/J m 0.0 0.2664 0.5328 -0.5328
C3H/HeJ f 1.0 0.2664 1.5328 0.4672
C3H/HeJ m 0.75 0.2664 1.2828 0.2172
C57BL/6J f 0.8333 0.2175 1.2683 0.3983
C57BL/6J m 0.8571 0.2014 1.2599 0.4544
DBA/2J f 0.4286 0.2014 0.8313 0.0258
DBA/2J m 0.0 0.3077 0.6152 -0.6152
FVB/NJ f 0.25 0.2664 0.7828 -0.2828
FVB/NJ m 0.3333 0.3077 0.9485 -0.2819


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 1.1667 0.2175 1.6017 0.7317
129S1/SvImJ both 0.125 0.1884 0.5017 -0.2517
A/J both 0.2917 0.2035 0.6986 -0.1152
BALB/cByJ both 0.25 0.1538 0.5576 -0.0576
BTBR T+ Itpr3tf/J both 0.125 0.1884 0.5017 -0.2517
C3H/HeJ both 0.875 0.1884 1.2517 0.4983
C57BL/6J both 0.8452 0.1482 1.1416 0.5488
DBA/2J both 0.2143 0.1839 0.5819 -0.1534
FVB/NJ both 0.2917 0.2035 0.6986 -0.1152




GWAS analysis not available: At least 12 strains are required