Project measure / variable:   Metten1   wobble_doseA_10min


  STRAIN COMPARISON PLOT
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Metten1 - erratic gait, 2.75 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.517   score 0.329   score
Median of the strain means0.429   score 0.250   score
SD of the strain means± 0.507 ± 0.391
Coefficient of variation (CV)0.979 1.19
Min–max range of strain means0   –   1.50   score 0   –   1.00   score
Mean sample size per strain4.7   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4137 0.4137 1.4615 0.2312
strain 8 12.9562 1.6195 5.7213 < 0.0001
sex:strain 8 0.7967 0.0996 0.3518 0.9415
Residuals 63 17.8333 0.2831


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 0.0 0.0   3 0.0 0.0 -1.02
129P3/J m 0.0 0.0   3 0.0 0.0 -0.84
129S1/SvImJ f 0.5 0.577   4 0.289 1.15 -0.03
129S1/SvImJ m 0.25 0.5   4 0.25 2.0 -0.2
A/J f 0.0 0.0   4 0.0 0.0 -1.02
A/J m 0.25 0.5   4 0.25 2.0 -0.2
BALB/cByJ f 0.143 0.378   7 0.143 2.65 -0.74
BALB/cByJ m 0.0 0.0   6 0.0 0.0 -0.84
BTBR T+ Itpr3tf/J f 0.25 0.5   4 0.25 2.0 -0.53
BTBR T+ Itpr3tf/J m 0.0 0.0   3 0.0 0.0 -0.84
C3H/HeJ f 1.0 1.41   4 0.707 1.41 0.95
C3H/HeJ m 0.75 0.5   4 0.25 0.667 1.08
C57BL/6J f 0.833 0.408   6 0.167 0.49 0.62
C57BL/6J m 0.714 0.488   7 0.184 0.683 0.98
DBA/2J f 0.429 0.787   7 0.297 1.84 -0.17
DBA/2J m 0.0 0.0   3 0.0 0.0 -0.84
FVB/NJ f 1.5 0.577   4 0.289 0.385 1.0, 2.0 1.94
FVB/NJ m 1.0 0.0   4 0.0 0.0 1.0, 1.0 1.72


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 0.0 0.3072 0.6138 -0.6138
129P3/J m 0.0 0.3072 0.6138 -0.6138
129S1/SvImJ f 0.5 0.266 1.0316 -0.0316
129S1/SvImJ m 0.25 0.266 0.7816 -0.2816
A/J f 0.0 0.266 0.5316 -0.5316
A/J m 0.25 0.266 0.7816 -0.2816
BALB/cByJ f 0.1429 0.2011 0.5447 -0.259
BALB/cByJ m 0.0 0.2172 0.4341 -0.4341
BTBR T+ Itpr3tf/J f 0.25 0.266 0.7816 -0.2816
BTBR T+ Itpr3tf/J m 0.0 0.3072 0.6138 -0.6138
C3H/HeJ f 1.0 0.266 1.5316 0.4684
C3H/HeJ m 0.75 0.266 1.2816 0.2184
C57BL/6J f 0.8333 0.2172 1.2674 0.3993
C57BL/6J m 0.7143 0.2011 1.1161 0.3124
DBA/2J f 0.4286 0.2011 0.8304 0.0267
DBA/2J m 0.0 0.3072 0.6138 -0.6138
FVB/NJ f 1.5 0.266 2.0316 0.9684
FVB/NJ m 1.0 0.266 1.5316 0.4684


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 0.0 0.2172 0.4341 -0.4341
129S1/SvImJ both 0.375 0.1881 0.7509 -0.0009
A/J both 0.125 0.1881 0.5009 -0.2509
BALB/cByJ both 0.0714 0.148 0.3672 -0.2243
BTBR T+ Itpr3tf/J both 0.125 0.2032 0.531 -0.281
C3H/HeJ both 0.875 0.1881 1.2509 0.4991
C57BL/6J both 0.7738 0.148 1.0696 0.4781
DBA/2J both 0.2143 0.1836 0.5811 -0.1526
FVB/NJ both 1.25 0.1881 1.6259 0.8741




GWAS analysis not available: At least 12 strains are required