Project measure / variable:   Metten1   splay_doseB_10min


  STRAIN COMPARISON PLOT
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Metten1 - hindlimb splay, 3.0 g/kg i.p. 10min after injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means3.38   score 2.73   score
Median of the strain means3.50   score 2.57   score
SD of the strain means± 1.12 ± 1.21
Coefficient of variation (CV)0.331 0.445
Min–max range of strain means1.25   –   5.00   score 1.00   –   5.00   score
Mean sample size per strain4.7   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 8.1742 8.1742 3.5464 0.0642
strain 8 63.3969 7.9246 3.4381 0.0023
sex:strain 8 18.6074 2.3259 1.0091 0.4381
Residuals 65 149.8214 2.3049


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 4.67 0.577   3 0.333 0.124 4.0, 5.0 1.15
129P3/J m 5.0 0.0   3 0.0 0.0 5.0, 5.0 1.87
129S1/SvImJ f 5.0 0.0   4 0.0 0.0 5.0, 5.0 1.44
129S1/SvImJ m 3.33 2.89   3 1.67 0.866 0.49
A/J f 3.0 1.15   4 0.577 0.385 2.0, 4.0 -0.34
A/J m 3.5 1.0   4 0.5 0.286 2.0, 4.0 0.63
BALB/cByJ f 2.67 1.86   6 0.76 0.698 -0.64
BALB/cByJ m 2.57 2.23   7 0.841 0.865 -0.13
BTBR T+ Itpr3tf/J f 3.75 1.89   4 0.946 0.505 1.0, 5.0 0.33
BTBR T+ Itpr3tf/J m 2.5 2.89   4 1.44 1.15 -0.19
C3H/HeJ f 3.75 0.5   4 0.25 0.133 3.0, 4.0 0.33
C3H/HeJ m 1.25 1.26   4 0.629 1.01 -1.22
C57BL/6J f 2.86 0.69   7 0.261 0.242 2.0, 4.0 -0.47
C57BL/6J m 3.17 1.17   6 0.477 0.369 2.0, 5.0 0.36
DBA/2J f 3.5 1.2   8 0.423 0.341 1.0, 5.0 0.1
DBA/2J m 2.25 1.26   4 0.629 0.559 1.0, 4.0 -0.4
FVB/NJ f 1.25 0.5   4 0.25 0.4 1.0, 2.0 -1.91
FVB/NJ m 1.0 2.0   4 1.0 2.0 -1.42


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 4.6667 0.8765 6.4172 2.9161
129P3/J m 5.0 0.8765 6.7506 3.2494
129S1/SvImJ f 5.0 0.7591 6.516 3.484
129S1/SvImJ m 3.3333 0.8765 5.0839 1.5828
A/J f 3.0 0.7591 4.516 1.484
A/J m 3.5 0.7591 5.016 1.984
BALB/cByJ f 2.6667 0.6198 3.9045 1.4288
BALB/cByJ m 2.5714 0.5738 3.7174 1.4254
BTBR T+ Itpr3tf/J f 3.75 0.7591 5.266 2.234
BTBR T+ Itpr3tf/J m 2.5 0.7591 4.016 0.984
C3H/HeJ f 3.75 0.7591 5.266 2.234
C3H/HeJ m 1.25 0.7591 2.766 0.0
C57BL/6J f 2.8571 0.5738 4.0032 1.7111
C57BL/6J m 3.1667 0.6198 4.4045 1.9288
DBA/2J f 3.5 0.5368 4.572 2.428
DBA/2J m 2.25 0.7591 3.766 0.734
FVB/NJ f 1.25 0.7591 2.766 0.0
FVB/NJ m 1.0 0.7591 2.516 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 4.8333 0.6198 6.0712 3.5955
129S1/SvImJ both 4.1667 0.5798 5.3246 3.0088
A/J both 3.25 0.5368 4.322 2.178
BALB/cByJ both 2.619 0.4223 3.4625 1.7756
BTBR T+ Itpr3tf/J both 3.125 0.5368 4.197 2.053
C3H/HeJ both 2.5 0.5368 3.572 1.428
C57BL/6J both 3.0119 0.4223 3.8553 2.1685
DBA/2J both 2.875 0.4649 3.8034 1.9466
FVB/NJ both 1.125 0.5368 2.197 0.053




GWAS analysis not available: At least 12 strains are required