Project measure / variable:   Metten1   line_doseB_pre

ID, description, units MPD:16502   line_doseB_pre   line crossings, 3.0 g/kg i.p.   [n]  pre-injection  
ethanol study
Data set, strains Metten1   inbred   9 strains     sex: both     age: 8-11wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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Metten1 - line crossings, 3.0 g/kg i.p. pre-injection



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means12.1   n 11.0   n
Median of the strain means11.5   n 12.1   n
SD of the strain means± 8.81 ± 8.11
Coefficient of variation (CV)0.727 0.736
Min–max range of strain means2.50   –   28.0   n 1.67   –   27.0   n
Mean sample size per strain4.7   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.8909 0.8909 0.036 0.8501
strain 8 4117.6426 514.7053 20.808 < 0.0001
sex:strain 8 282.6355 35.3294 1.4283 0.2028
Residuals 62 1533.631 24.736


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129P3/J f 23.0 5.0   3 2.89 0.217 18.0, 28.0 1.24
129P3/J m 14.7 1.15   3 0.667 0.0787 14.0, 16.0 0.45
129S1/SvImJ f 4.0 2.16   4 1.08 0.54 2.0, 7.0 -0.92
129S1/SvImJ m 4.25 3.3   4 1.65 0.777 2.0, 9.0 -0.83
A/J f 2.5 1.0   4 0.5 0.4 2.0, 4.0 -1.09
A/J m 1.67 2.08   3 1.2 1.25 -1.15
BALB/cByJ f 6.17 5.0   6 2.04 0.81 -0.67
BALB/cByJ m 12.1 5.27   7 1.99 0.434 4.0, 19.0 0.13
BTBR T+ Itpr3tf/J f 28.0 10.7   4 5.34 0.381 16.0, 37.0 1.8
BTBR T+ Itpr3tf/J m 27.0 10.5   3 6.08 0.39 17.0, 38.0 1.97
C3H/HeJ f 12.0 6.0   4 3.0 0.5 7.0, 19.0 -0.01
C3H/HeJ m 8.0 6.0   3 3.46 0.75 2.0, 14.0 -0.37
C57BL/6J f 16.1 2.54   7 0.962 0.158 13.0, 19.0 0.45
C57BL/6J m 17.0 4.74   5 2.12 0.279 9.0, 21.0 0.74
DBA/2J f 5.75 3.99   8 1.41 0.694 2.0, 12.0 -0.72
DBA/2J m 2.25 0.5   4 0.25 0.222 2.0, 3.0 -1.08
FVB/NJ f 11.5 3.87   4 1.94 0.337 7.0, 16.0 -0.07
FVB/NJ m 12.2 5.8   4 2.9 0.473 6.0, 20.0 0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129P3/J f 23.0 2.8715 28.74 17.26
129P3/J m 14.6667 2.8715 20.4066 8.9267
129S1/SvImJ f 4.0 2.4868 8.971 0.0
129S1/SvImJ m 4.25 2.4868 9.221 0.0
A/J f 2.5 2.4868 7.471 0.0
A/J m 1.6667 2.8715 7.4066 0.0
BALB/cByJ f 6.1667 2.0304 10.2254 2.1079
BALB/cByJ m 12.1429 1.8798 15.9006 8.3852
BTBR T+ Itpr3tf/J f 28.0 2.4868 32.971 23.029
BTBR T+ Itpr3tf/J m 27.0 2.8715 32.74 21.26
C3H/HeJ f 12.0 2.4868 16.971 7.029
C3H/HeJ m 8.0 2.8715 13.74 2.26
C57BL/6J f 16.1429 1.8798 19.9006 12.3852
C57BL/6J m 17.0 2.2242 21.4462 12.5538
DBA/2J f 5.75 1.7584 9.265 2.235
DBA/2J m 2.25 2.4868 7.221 0.0
FVB/NJ f 11.5 2.4868 16.471 6.529
FVB/NJ m 12.25 2.4868 17.221 7.279


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129P3/J both 18.8333 2.0304 22.8921 14.7746
129S1/SvImJ both 4.125 1.7584 7.64 0.61
A/J both 2.0833 1.8993 5.88 0.0
BALB/cByJ both 9.1548 1.3835 11.9204 6.3892
BTBR T+ Itpr3tf/J both 27.5 1.8993 31.2966 23.7034
C3H/HeJ both 10.0 1.8993 13.7966 6.2034
C57BL/6J both 16.5714 1.4561 19.4821 13.6607
DBA/2J both 4.0 1.5228 7.0441 0.9559
FVB/NJ both 11.875 1.7584 15.39 8.36




  GWAS USING LINEAR MIXED MODELS