Project measure / variable:   Crabbe3   ARR2_post_20rpm

ID, description, units MPD:15856   ARR2_post_20rpm   latency to fall, accelerating rotarod, 20 rpm/min (ARR2)   [s]  ethanol  
ethanol study
Data set, strains Crabbe3   inbred   21 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, accelerating rotarod, 20 rpm/min (ARR2) ethanol



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means45.8   s 40.5   s
Median of the strain means44.3   s 41.1   s
SD of the strain means± 17.0 ± 14.9
Coefficient of variation (CV)0.372 0.368
Min–max range of strain means20.5   –   76.2   s 17.0   –   69.5   s
Mean sample size per strain9.4   mice 9.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1341.555 1341.555 2.6257 0.1061
strain 20 83199.7723 4159.9886 8.142 < 0.0001
sex:strain 20 10284.8957 514.2448 1.0065 0.4536
Residuals 344 175759.775 510.9296


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 20.5 14.8   10 4.69 0.724 7.0, 54.5 -1.48
129S1/SvImJ m 19.5 8.91   10 2.82 0.457 7.5, 36.5 -1.41
A/J f 27.6 19.0   8 6.71 0.689 9.0, 67.0 -1.07
A/J m 19.7 15.3   10 4.85 0.778 3.5, 56.0 -1.4
AKR/J f 46.3 14.9   9 4.96 0.321 25.0, 72.0 0.03
AKR/J m 63.9 9.31   8 3.29 0.146 53.0, 79.5 1.57
BALB/cByJ f 62.1 21.2   10 6.69 0.341 28.0, 92.5 0.96
BALB/cByJ m 46.4 20.4   10 6.44 0.439 6.5, 77.5 0.39
BTBR T+ Itpr3tf/J f 22.6 17.3   12 5.0 0.765 6.0, 52.5 -1.36
BTBR T+ Itpr3tf/J m 17.0 11.4   6 4.64 0.669 8.0, 36.0 -1.58
C3H/HeJ f 30.1 15.3   10 4.83 0.508 17.0, 58.0 -0.92
C3H/HeJ m 21.3 9.03   8 3.19 0.424 12.0, 36.0 -1.29
C57BL/6J f 38.2 13.7   8 4.83 0.357 12.5, 57.0 -0.45
C57BL/6J m 43.8 10.5   10 3.33 0.24 27.5, 57.5 0.22
C57L/J f 32.8 14.8   10 4.69 0.453 9.5, 60.0 -0.76
C57L/J m 29.3 14.6   8 5.17 0.499 11.5, 61.5 -0.75
C58/J f 59.6 38.4   10 12.2 0.645 3.0, 110.0 0.81
C58/J m 43.1 23.0   10 7.28 0.534 8.0, 73.0 0.17
CAST/EiJ f 69.1 33.4   5 14.9 0.483 32.0, 104.0 1.37
CAST/EiJ m 60.8 23.1   8 8.17 0.38 25.0, 85.0 1.36
DBA/2J f 37.8 20.7   10 6.53 0.547 14.5, 74.5 -0.47
DBA/2J m 30.7 15.1   8 5.34 0.492 12.5, 58.0 -0.66
FVB/NJ f 50.4 23.4   10 7.41 0.465 11.0, 81.5 0.27
FVB/NJ m 35.8 19.0   11 5.71 0.53 16.5, 74.0 -0.32
MOLF/EiJ f 76.2 44.3   8 15.6 0.581 26.5, 140.0 1.78
MOLF/EiJ m 41.1 30.1   6 12.3 0.734 4.0, 76.0 0.04
NOD/ShiLtJ f 67.3 27.7   12 7.98 0.411 22.5, 113.0 1.26
NOD/ShiLtJ m 57.7 32.6   12 9.41 0.565 6.0, 98.0 1.15
NZB/BlNJ f 30.6 8.33   6 3.4 0.272 19.5, 43.5 -0.89
NZB/BlNJ m 37.2 19.7   12 5.68 0.53 7.0, 65.5 -0.22
PERA/EiJ f 54.8 37.1   10 11.7 0.678 5.0, 109.0 0.53
PERA/EiJ m 55.4 12.9   12 3.72 0.233 36.5, 73.0 1.0
PL/J f 31.7 20.7   12 5.98 0.653 1.5, 62.0 -0.83
PL/J m 41.9 22.4   8 7.92 0.534 14.0, 81.0 0.09
SJL/J f 34.2 13.8   8 4.88 0.404 9.0, 51.5 -0.68
SJL/J m 37.1 12.7   12 3.67 0.342 18.0, 55.0 -0.23
SM/J f 44.3 23.2   14 6.2 0.523 15.5, 92.5 -0.09
SM/J m 43.0 24.9   10 7.86 0.579 12.5, 71.0 0.17
SPRET/EiJ f 54.5 18.2   3 10.5 0.334 43.5, 75.5 0.51
SPRET/EiJ m 37.0 17.0   2   12.0 0.459 25.0, 49.0 -0.24
SWR/J f 71.0 30.2   10 9.54 0.425 31.0, 119.0 1.48
SWR/J m 69.5 41.4   10 13.1 0.596 18.0, 150.0 1.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 20.5 7.1479 34.5592 6.4408
129S1/SvImJ m 19.5 7.1479 33.5592 5.4408
A/J f 27.5625 7.9916 43.2811 11.8439
A/J m 19.7 7.1479 33.7592 5.6408
AKR/J f 46.3333 7.5346 61.153 31.5137
AKR/J m 63.9375 7.9916 79.6561 48.2189
BALB/cByJ f 62.15 7.1479 76.2092 48.0908
BALB/cByJ m 46.4 7.1479 60.4592 32.3408
BTBR T+ Itpr3tf/J f 22.625 6.5251 35.4592 9.7908
BTBR T+ Itpr3tf/J m 17.0 9.2279 35.1503 0.0
C3H/HeJ f 30.05 7.1479 44.1092 15.9908
C3H/HeJ m 21.3125 7.9916 37.0311 5.5939
C57BL/6J f 38.25 7.9916 53.9686 22.5314
C57BL/6J m 43.75 7.1479 57.8092 29.6908
C57L/J f 32.75 7.1479 46.8092 18.6908
C57L/J m 29.3125 7.9916 45.0311 13.5939
C58/J f 59.6 7.1479 73.6592 45.5408
C58/J m 43.15 7.1479 57.2092 29.0908
CAST/EiJ f 69.1 10.1087 88.9827 49.2173
CAST/EiJ m 60.8125 7.9916 76.5311 45.0939
DBA/2J f 37.8 7.1479 51.8592 23.7408
DBA/2J m 30.6875 7.9916 46.4061 14.9689
FVB/NJ f 50.4 7.1479 64.4592 36.3408
FVB/NJ m 35.7727 6.8153 49.1776 22.3678
MOLF/EiJ f 76.1875 7.9916 91.9061 60.4689
MOLF/EiJ m 41.0833 9.2279 59.2336 22.933
NOD/ShiLtJ f 67.3333 6.5251 80.1675 54.4991
NOD/ShiLtJ m 57.7083 6.5251 70.5425 44.8741
NZB/BlNJ f 30.5833 9.2279 48.7336 12.433
NZB/BlNJ m 37.1667 6.5251 50.0009 24.3325
PERA/EiJ f 54.75 7.1479 68.8092 40.6908
PERA/EiJ m 55.375 6.5251 68.2092 42.5408
PL/J f 31.7083 6.5251 44.5425 18.8741
PL/J m 41.9375 7.9916 57.6561 26.2189
SJL/J f 34.1875 7.9916 49.9061 18.4689
SJL/J m 37.125 6.5251 49.9592 24.2908
SM/J f 44.3214 6.0411 56.2036 32.4393
SM/J m 42.95 7.1479 57.0092 28.8908
SPRET/EiJ f 54.5 13.0503 80.1684 28.8316
SPRET/EiJ m 37.0 15.9833 68.4372 5.5628
SWR/J f 71.05 7.1479 85.1092 56.9908
SWR/J m 69.45 7.1479 83.5092 55.3908


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 20.0 5.0544 29.9413 10.0587
A/J both 23.6313 5.361 34.1756 13.0869
AKR/J both 55.1354 5.4917 65.937 44.3338
BALB/cByJ both 54.275 5.0544 64.2163 44.3337
BTBR T+ Itpr3tf/J both 19.8125 5.6509 30.9272 8.6978
C3H/HeJ both 25.6812 5.361 36.2256 15.1369
C57BL/6J both 41.0 5.361 51.5444 30.4556
C57L/J both 31.0313 5.361 41.5756 20.4869
C58/J both 51.375 5.0544 61.3163 41.4337
CAST/EiJ both 64.9563 6.4431 77.629 52.2835
DBA/2J both 34.2437 5.361 44.7881 23.6994
FVB/NJ both 43.0864 4.9381 52.7991 33.3736
MOLF/EiJ both 58.6354 6.1037 70.6407 46.6301
NOD/ShiLtJ both 62.5208 4.614 71.596 53.4457
NZB/BlNJ both 33.875 5.6509 44.9897 22.7603
PERA/EiJ both 55.0625 4.8392 64.5806 45.5444
PL/J both 36.8229 5.1586 46.9692 26.6766
SJL/J both 35.6563 5.1586 45.8026 25.5099
SM/J both 43.6357 4.6794 52.8396 34.4318
SPRET/EiJ both 45.75 10.3172 66.0426 25.4574
SWR/J both 70.25 5.0544 80.1913 60.3087




  GWAS USING LINEAR MIXED MODELS