Project measure / variable:   Crabbe3   ARR1_chg_30rpm

ID, description, units MPD:15847   ARR1_chg_30rpm   latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1)   [s]  difference  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) difference



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means-1.05   s 5.50   s
Median of the strain means0.910   s 8.58   s
SD of the strain means± 11.3 ± 11.0
Coefficient of variation (CV)-10.7 2.00
Min–max range of strain means-19.8   –   13.6   s -12.2   –   18.6   s
Mean sample size per strain4.6   mice 4.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 748.1866 748.1866 2.4361 0.1242
strain 7 5849.8135 835.6876 2.721 0.0168
sex:strain 7 754.9053 107.8436 0.3511 0.9263
Residuals 56 17198.8733 307.1227


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f -15.3 9.49   5 4.24 -0.622 -27.9, -3.6 -1.26
129S1/SvImJ m -2.68 12.0   5 5.39 -4.49 -21.5, 12.1 -0.75
A/J f 2.1 11.4   5 5.12 5.45 -14.6, 16.4 0.28
A/J m 6.86 10.2   5 4.57 1.49 -4.3, 19.7 0.12
BALB/cByJ f 8.02 28.6   5 12.8 3.56 -27.4, 48.2 0.8
BALB/cByJ m 18.6 9.67   3 5.58 0.519 10.7, 29.4 1.2
BTBR T+ Itpr3tf/J f -19.8 27.9   3 16.1 -1.41 -36.0, 12.4 -1.66
BTBR T+ Itpr3tf/J m -12.2 0.0   2   0.0 0.0 -12.2, -12.2 -1.61
C3H/HeJ f -0.28 14.3   5 6.41 -51.2 -17.0, 17.0 0.07
C3H/HeJ m -5.22 14.0   5 6.25 -2.68 -22.9, 10.7 -0.98
C57BL/6J f -1.14 15.3   5 6.83 -13.4 -23.8, 15.9 -0.01
C57BL/6J m 14.3 34.3   5 15.3 2.39 -11.9, 70.8 0.8
DBA/2J f 4.4 7.28   4 3.64 1.65 -4.3, 13.4 0.48
DBA/2J m 10.3 14.5   5 6.48 1.41 -8.9, 21.5 0.44
FVB/NJ f 13.6 14.0   5 6.28 1.03 0.7, 34.9 1.3
FVB/NJ m 14.0 17.9   5 8.02 1.28 -6.4, 34.1 0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f -15.26 7.8374 0.4402 -30.9602
129S1/SvImJ m -2.68 7.8374 13.0202 -18.3802
A/J f 2.1 7.8374 17.8002 -13.6002
A/J m 6.86 7.8374 22.5602 -8.8402
BALB/cByJ f 8.02 7.8374 23.7202 -7.6802
BALB/cByJ m 18.6333 10.118 38.9022 -1.6355
BTBR T+ Itpr3tf/J f -19.8333 10.118 0.4355 -40.1022
BTBR T+ Itpr3tf/J m -12.2 12.392 12.6241 -37.0241
C3H/HeJ f -0.28 7.8374 15.4202 -15.9802
C3H/HeJ m -5.22 7.8374 10.4802 -20.9202
C57BL/6J f -1.14 7.8374 14.5602 -16.8402
C57BL/6J m 14.34 7.8374 30.0402 -1.3602
DBA/2J f 4.4 8.7625 21.9533 -13.1533
DBA/2J m 10.26 7.8374 25.9602 -5.4402
FVB/NJ f 13.6 7.8374 29.3002 -2.1002
FVB/NJ m 14.02 7.8374 29.7202 -1.6802


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both -8.97 5.5419 2.1317 -20.0717
A/J both 4.48 5.5419 15.5817 -6.6217
BALB/cByJ both 13.3267 6.3992 26.1458 0.5075
BTBR T+ Itpr3tf/J both -16.0167 7.999 0.0072 -32.0406
C3H/HeJ both -2.75 5.5419 8.3517 -13.8517
C57BL/6J both 6.6 5.5419 17.7017 -4.5017
DBA/2J both 7.33 5.878 19.1051 -4.4451
FVB/NJ both 13.81 5.5419 24.9117 2.7083




  GWAS USING LINEAR MIXED MODELS