Project measure / variable:   Crabbe3   ARR1_pre_30rpm

ID, description, units MPD:15845   ARR1_pre_30rpm   latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1)   [s]  baseline  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means26.2   s 22.9   s
Median of the strain means21.0   s 21.8   s
SD of the strain means± 12.7 ± 8.33
Coefficient of variation (CV)0.483 0.364
Min–max range of strain means13.9   –   52.3   s 13.2   –   37.7   s
Mean sample size per strain6.6   mice 6.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 352.5634 352.5634 3.9757 0.0493
strain 7 8002.2477 1143.1782 12.8911 < 0.0001
sex:strain 7 773.4533 110.4933 1.246 0.2869
Residuals 87 7715.1394 88.6798


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.2 7.65   7 2.89 0.329 13.3, 35.1 -0.24
129S1/SvImJ m 28.5 9.63   7 3.64 0.338 8.7, 38.2 0.67
A/J f 20.6 7.74   7 2.92 0.376 8.2, 32.3 -0.44
A/J m 17.0 10.2   7 3.85 0.6 6.5, 38.5 -0.71
BALB/cByJ f 21.4 8.82   7 3.33 0.412 10.9, 35.2 -0.38
BALB/cByJ m 21.7 8.66   5 3.87 0.399 15.3, 36.8 -0.14
BTBR T+ Itpr3tf/J f 52.3 16.6   5 7.41 0.317 31.8, 71.7 2.06
BTBR T+ Itpr3tf/J m 37.7 23.5   3 13.5 0.623 19.3, 64.1 1.78
C3H/HeJ f 20.6 6.66   7 2.52 0.323 12.1, 27.8 -0.44
C3H/HeJ m 21.9 7.54   7 2.85 0.343 10.3, 31.6 -0.12
C57BL/6J f 38.4 11.4   7 4.33 0.298 22.5, 52.0 0.96
C57BL/6J m 28.7 11.4   7 4.33 0.398 12.5, 44.8 0.7
DBA/2J f 13.9 3.22   6 1.31 0.231 8.7, 17.8 -0.97
DBA/2J m 13.2 3.34   7 1.26 0.252 7.4, 18.2 -1.16
FVB/NJ f 19.3 7.16   7 2.71 0.371 12.4, 29.0 -0.55
FVB/NJ m 14.5 6.52   7 2.46 0.45 8.8, 26.0 -1.01


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.2143 3.5593 30.2888 16.1398
129S1/SvImJ m 28.4714 3.5593 35.5459 21.397
A/J f 20.5714 3.5593 27.6459 13.497
A/J m 16.9714 3.5593 24.0459 9.897
BALB/cByJ f 21.3857 3.5593 28.4602 14.3112
BALB/cByJ m 21.7 4.2114 30.0706 13.3294
BTBR T+ Itpr3tf/J f 52.32 4.2114 60.6906 43.9494
BTBR T+ Itpr3tf/J m 37.6667 5.4369 48.4731 26.8602
C3H/HeJ f 20.6429 3.5593 27.7173 13.5684
C3H/HeJ m 21.9429 3.5593 29.0173 14.8684
C57BL/6J f 38.4 3.5593 45.4745 31.3255
C57BL/6J m 28.7286 3.5593 35.803 21.6541
DBA/2J f 13.9333 3.8445 21.5746 6.292
DBA/2J m 13.2286 3.5593 20.303 6.1541
FVB/NJ f 19.3143 3.5593 26.3888 12.2398
FVB/NJ m 14.5 3.5593 21.5745 7.4255


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 25.8429 2.5168 30.8453 20.8404
A/J both 18.7714 2.5168 23.7738 13.769
BALB/cByJ both 21.5429 2.757 27.0227 16.063
BTBR T+ Itpr3tf/J both 44.9933 3.4386 51.8279 38.1587
C3H/HeJ both 21.2929 2.5168 26.2953 16.2904
C57BL/6J both 33.5643 2.5168 38.5667 28.5619
DBA/2J both 13.581 2.6196 18.7876 8.3743
FVB/NJ both 16.9071 2.5168 21.9096 11.9047




  GWAS USING LINEAR MIXED MODELS