Project measure / variable:   Crabbe3   ARR1_post_20rpm

ID, description, units MPD:15841   ARR1_post_20rpm   latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1)   [s]  ethanol  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) ethanol



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means30.1   s 26.8   s
Median of the strain means28.8   s 24.4   s
SD of the strain means± 12.6 ± 13.7
Coefficient of variation (CV)0.418 0.512
Min–max range of strain means11.1   –   51.4   s 8.20   –   50.4   s
Mean sample size per strain5.9   mice 5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 197.9881 197.9881 0.6711 0.4154
strain 7 8672.0019 1238.8574 4.1993 0.0006
sex:strain 7 3091.208 441.6011 1.4969 0.1824
Residuals 71 20946.0712 295.0151


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 11.1 9.17   6 3.75 0.826 6.7, 29.8 -1.51
129S1/SvImJ m 28.4 22.7   6 9.26 0.797 7.0, 64.9 0.12
A/J f 26.5 16.8   6 6.87 0.636 9.8, 47.0 -0.29
A/J m 20.4 12.3   6 5.02 0.604 4.9, 39.5 -0.47
BALB/cByJ f 39.6 15.7   6 6.42 0.398 12.0, 58.2 0.76
BALB/cByJ m 50.4 13.3   4 6.67 0.265 39.6, 69.8 1.72
BTBR T+ Itpr3tf/J f 37.4 36.8   5 16.5 0.986 5.5, 89.5 0.58
BTBR T+ Itpr3tf/J m 8.2 0.99   2   0.7 0.121 7.5, 8.9 -1.35
C3H/HeJ f 22.2 13.2   6 5.38 0.593 4.7, 41.1 -0.63
C3H/HeJ m 14.6 7.95   6 3.24 0.544 4.1, 26.7 -0.89
C57BL/6J f 51.4 21.2   6 8.64 0.411 19.5, 83.0 1.69
C57BL/6J m 38.1 9.95   4 4.98 0.261 30.1, 51.5 0.82
DBA/2J f 21.5 16.5   6 6.75 0.769 10.3, 49.5 -0.68
DBA/2J m 20.2 16.9   6 6.89 0.836 1.8, 42.0 -0.48
FVB/NJ f 31.0 12.4   6 5.07 0.4 9.6, 41.8 0.07
FVB/NJ m 34.0 16.1   6 6.59 0.475 8.5, 56.7 0.53


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 11.1 7.0121 25.0817 0.0
129S1/SvImJ m 28.45 7.0121 42.4317 14.4683
A/J f 26.4667 7.0121 40.4483 12.485
A/J m 20.3667 7.0121 34.3483 6.385
BALB/cByJ f 39.5833 7.0121 53.565 25.6017
BALB/cByJ m 50.35 8.588 67.474 33.226
BTBR T+ Itpr3tf/J f 37.36 7.6813 52.6762 22.0438
BTBR T+ Itpr3tf/J m 8.2 12.1453 32.417 0.0
C3H/HeJ f 22.2 7.0121 36.1817 8.2183
C3H/HeJ m 14.6 7.0121 28.5817 0.6183
C57BL/6J f 51.45 7.0121 65.4317 37.4683
C57BL/6J m 38.125 8.588 55.249 21.001
DBA/2J f 21.4833 7.0121 35.465 7.5017
DBA/2J m 20.2 7.0121 34.1817 6.2183
FVB/NJ f 31.05 7.0121 45.0317 17.0683
FVB/NJ m 34.0333 7.0121 48.015 20.0517


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.775 4.9583 29.6615 9.8885
A/J both 23.4167 4.9583 33.3032 13.5301
BALB/cByJ both 44.9667 5.5435 56.0202 33.9132
BTBR T+ Itpr3tf/J both 22.78 7.1852 37.107 8.453
C3H/HeJ both 18.4 4.9583 28.2865 8.5135
C57BL/6J both 44.7875 5.5435 55.841 33.734
DBA/2J both 20.8417 4.9583 30.7282 10.9551
FVB/NJ both 32.5417 4.9583 42.4282 22.6551




  GWAS USING LINEAR MIXED MODELS