Project measure / variable:   Crabbe3   ARR1_pre_20rpm

ID, description, units MPD:15840   ARR1_pre_20rpm   latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1)   [s]  baseline  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to-fall, accelerating rotarod, test day 1 20 rpm/min (ARR1) baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means30.8   s 28.8   s
Median of the strain means26.1   s 26.6   s
SD of the strain means± 13.7 ± 10.7
Coefficient of variation (CV)0.445 0.373
Min–max range of strain means17.7   –   52.9   s 17.4   –   50.6   s
Mean sample size per strain6.6   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 173.8847 173.8847 1.3351 0.251
strain 7 11437.9485 1633.9926 12.546 < 0.0001
sex:strain 7 764.9375 109.2768 0.839 0.558
Residuals 88 11461.1592 130.2404


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 31.8 10.9   7 4.14 0.345 14.9, 50.1 0.08
129S1/SvImJ m 32.3 13.2   7 4.99 0.408 6.2, 45.2 0.33
A/J f 22.9 5.8   7 2.19 0.253 10.8, 28.9 -0.57
A/J m 22.3 9.3   7 3.52 0.418 11.3, 39.4 -0.6
BALB/cByJ f 29.3 10.9   7 4.13 0.372 16.0, 41.8 -0.11
BALB/cByJ m 28.2 14.2   5 6.34 0.503 17.9, 53.2 -0.05
BTBR T+ Itpr3tf/J f 52.9 23.2   5 10.4 0.438 15.1, 70.7 1.62
BTBR T+ Itpr3tf/J m 50.6 17.8   4 8.91 0.352 27.6, 68.6 2.03
C3H/HeJ f 20.7 12.6   6 5.13 0.607 9.0, 39.3 -0.73
C3H/HeJ m 25.0 10.1   7 3.83 0.406 16.6, 41.6 -0.35
C57BL/6J f 50.2 12.5   7 4.71 0.248 36.4, 68.3 1.42
C57BL/6J m 35.1 11.4   7 4.32 0.325 25.1, 58.5 0.59
DBA/2J f 17.7 6.17   7 2.33 0.349 8.9, 27.0 -0.95
DBA/2J m 17.4 7.86   7 2.97 0.45 12.3, 34.7 -1.06
FVB/NJ f 20.5 4.97   7 1.88 0.243 9.7, 24.1 -0.75
FVB/NJ m 19.2 8.98   7 3.39 0.468 10.8, 32.7 -0.89


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 31.7714 4.3134 40.3435 23.1994
129S1/SvImJ m 32.3429 4.3134 40.9149 23.7708
A/J f 22.9143 4.3134 31.4863 14.3422
A/J m 22.2857 4.3134 30.8578 13.7137
BALB/cByJ f 29.3143 4.3134 37.8863 20.7422
BALB/cByJ m 28.18 5.1037 38.3226 18.0374
BTBR T+ Itpr3tf/J f 52.9 5.1037 63.0426 42.7574
BTBR T+ Itpr3tf/J m 50.6 5.7061 61.9398 39.2602
C3H/HeJ f 20.7167 4.659 29.9755 11.4578
C3H/HeJ m 24.9571 4.3134 33.5292 16.3851
C57BL/6J f 50.1714 4.3134 58.7435 41.5994
C57BL/6J m 35.1429 4.3134 43.7149 26.5708
DBA/2J f 17.6571 4.3134 26.2292 9.0851
DBA/2J m 17.4429 4.3134 26.0149 8.8708
FVB/NJ f 20.4714 4.3134 29.0435 11.8994
FVB/NJ m 19.1857 4.3134 27.7578 10.6137


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 32.0571 3.0501 38.1185 25.9958
A/J both 22.6 3.0501 28.6614 16.5386
BALB/cByJ both 28.7471 3.3412 35.387 22.1073
BTBR T+ Itpr3tf/J both 51.75 3.8278 59.3569 44.1431
C3H/HeJ both 22.8369 3.1746 29.1458 16.528
C57BL/6J both 42.6571 3.0501 48.7185 36.5958
DBA/2J both 17.55 3.0501 23.6114 11.4886
FVB/NJ both 19.8286 3.0501 25.8899 13.7672




  GWAS USING LINEAR MIXED MODELS