Project measure / variable:   Crabbe3   FS_10rpm_EtOH_3

ID, description, units MPD:15822   FS_10rpm_EtOH_3   latency to fall, fixed speed 10 rpm rotarod   [s]  dose: 3 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 10 rpm rotarod dose: 3 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means57.0   s 55.6   s
Median of the strain means57.3   s 54.1   s
SD of the strain means± 13.5 ± 15.1
Coefficient of variation (CV)0.237 0.272
Min–max range of strain means39.0   –   79.7   s 41.4   –   89.0   s
Mean sample size per strain2.6   mice 2.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 78.9123 78.9123 0.0778 0.7835
strain 4 2461.4536 615.3634 0.6068 0.6629
sex:strain 4 1973.381 493.3452 0.4865 0.7455
Residuals 18 18254.0217 1014.1123


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 67.5 48.4   4 24.2 0.717 42.6, 140.0 0.78
129S1/SvImJ m 52.7 23.6   4 11.8 0.448 29.8, 84.5 -0.19
A/J f 54.8 0.0   1   0.0 0.0 54.8, 54.8 -0.16
A/J m 60.5 0.0   1   0.0 0.0 60.5, 60.5 0.32
B6D2F1/J m 45.6 11.5   2   8.1 0.251 37.5, 53.7 -0.66
BALB/cByJ f 59.8 5.23   2   3.7 0.0875 56.1, 63.5 0.21
BALB/cByJ m 89.0 58.1   2   41.0 0.653 47.9, 130.0 2.2
BTBR T+ Itpr3tf/J f 39.0 3.01   3 1.74 0.0771 37.1, 42.5 -1.33
BTBR T+ Itpr3tf/J m 57.1 0.0   1   0.0 0.0 57.1, 57.1 0.1
C3H/HeJ f 46.4 14.4   2   10.2 0.31 36.2, 56.5 -0.78
C3H/HeJ m 55.5 4.6   2   3.25 0.0829 52.2, 58.7 -0.01
C57BL/6J f 44.6 14.0   3 8.1 0.315 34.5, 60.6 -0.92
C57BL/6J m 43.2 27.4   3 15.8 0.635 19.8, 73.4 -0.82
DBA/2J f 79.7 34.4   2   24.3 0.432 55.3, 104.0 1.68
FVB/NJ f 64.0 35.8   4 17.9 0.559 29.2, 114.0 0.52
FVB/NJ m 41.4 14.0   2   9.9 0.338 31.5, 51.3 -0.94


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 67.45 15.9226 100.9021 33.9979
129S1/SvImJ m 52.65 15.9226 86.1021 19.1979
BALB/cByJ f 59.8 22.5179 107.1084 12.4916
BALB/cByJ m 88.95 22.5179 136.2584 41.6416
C3H/HeJ f 46.35 22.5179 93.6584 0.0
C3H/HeJ m 55.45 22.5179 102.7584 8.1416
C57BL/6J f 44.5667 18.3858 83.1938 5.9395
C57BL/6J m 43.2 18.3858 81.8271 4.5729
FVB/NJ f 64.0 15.9226 97.4521 30.5479
FVB/NJ m 41.4 22.5179 88.7084 0.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 60.05 11.259 83.7042 36.3958
BALB/cByJ both 74.375 15.9226 107.8271 40.9229
C3H/HeJ both 50.9 15.9226 84.3521 17.4479
C57BL/6J both 43.8833 13.0007 71.1968 16.5698
FVB/NJ both 52.7 13.7893 81.6703 23.7297




GWAS analysis not available: At least 12 strains are required