Project measure / variable:   Crabbe3   FS_6rpm_EtOH_3

ID, description, units MPD:15817   FS_6rpm_EtOH_3   latency to fall, fixed speed 6 rpm rotarod   [s]  dose: 3 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 6 rpm rotarod dose: 3 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means63.8   s 57.0   s
Median of the strain means53.2   s 53.2   s
SD of the strain means± 23.3 ± 25.7
Coefficient of variation (CV)0.366 0.452
Min–max range of strain means46.4   –   120   s 30.3   –   117   s
Mean sample size per strain3.7   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1005.4857 1005.4857 0.9169 0.3434
strain 8 11439.7948 1429.9744 1.3039 0.266
sex:strain 8 17711.6678 2213.9585 2.0188 0.0657
Residuals 45 49349.9117 1096.6647


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 49.2 22.4   4 11.2 0.456 31.8, 82.0 -0.63
129S1/SvImJ m 42.1 5.73   4 2.86 0.136 35.2, 48.9 -0.58
A/J f 63.4 39.6   3 22.9 0.625 37.0, 109.0 -0.02
A/J m 38.9 2.83   2   2.0 0.0727 36.9, 40.9 -0.7
B6D2F1/J f 46.4 14.7   4 7.36 0.317 28.3, 60.8 -0.75
B6D2F1/J m 73.9 39.8   4 19.9 0.538 43.9, 129.0 0.66
BALB/cByJ f 69.5 11.1   3 6.43 0.16 57.5, 79.5 0.24
BALB/cByJ m 56.1 12.1   4 6.03 0.215 44.5, 69.4 -0.04
BTBR T+ Itpr3tf/J f 53.2 14.6   3 8.42 0.274 37.6, 66.5 -0.46
BTBR T+ Itpr3tf/J m 117.0 89.1   2   63.0 0.761 54.0, 180.0 2.33
C3H/HeJ f 46.8 7.07   4 3.53 0.151 36.7, 53.2 -0.73
C3H/HeJ m 56.3 8.95   4 4.47 0.159 43.2, 62.0 -0.03
C57BL/6J f 74.2 70.5   4 35.3 0.95 37.1, 180.0 0.44
C57BL/6J m 45.3 13.9   4 6.94 0.307 32.1, 62.0 -0.45
DBA/2J f 51.9 14.7   4 7.36 0.284 35.5, 66.8 -0.51
DBA/2J m 30.3 6.65   2   4.7 0.219 25.6, 35.0 -1.04
FVB/NJ f 120.0 64.9   4 32.5 0.542 49.5, 180.0 2.41
FVB/NJ m 53.2 17.4   4 8.69 0.326 32.1, 74.4 -0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 49.2 16.558 82.5495 15.8505
129S1/SvImJ m 42.125 16.558 75.4745 8.7755
A/J f 63.4333 19.1195 101.942 24.9247
A/J m 38.9 23.4165 86.0632 0.0
B6D2F1/J f 46.4 16.558 79.7495 13.0505
B6D2F1/J m 73.925 16.558 107.2745 40.5755
BALB/cByJ f 69.5 19.1195 108.0086 30.9914
BALB/cByJ m 56.05 16.558 89.3995 22.7005
BTBR T+ Itpr3tf/J f 53.2 19.1195 91.7086 14.6914
BTBR T+ Itpr3tf/J m 117.0 23.4165 164.1632 69.8368
C3H/HeJ f 46.775 16.558 80.1245 13.4255
C3H/HeJ m 56.35 16.558 89.6995 23.0005
C57BL/6J f 74.25 16.558 107.5995 40.9005
C57BL/6J m 45.275 16.558 78.6245 11.9255
DBA/2J f 51.925 16.558 85.2745 18.5755
DBA/2J m 30.3 23.4165 77.4632 0.0
FVB/NJ f 119.925 16.558 153.2745 86.5755
FVB/NJ m 53.25 16.558 86.5995 19.9005


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 45.6625 11.7082 69.2441 22.0809
A/J both 51.1667 15.1153 81.6104 20.7229
B6D2F1/J both 60.1625 11.7082 83.7441 36.5809
BALB/cByJ both 62.775 12.6464 88.2461 37.3039
BTBR T+ Itpr3tf/J both 85.1 15.1153 115.5437 54.6563
C3H/HeJ both 51.5625 11.7082 75.1441 27.9809
C57BL/6J both 59.7625 11.7082 83.3441 36.1809
DBA/2J both 41.1125 14.3396 69.994 12.231
FVB/NJ both 86.5875 11.7082 110.1691 63.0059




  GWAS USING LINEAR MIXED MODELS