Project measure / variable:   Crabbe3   FS_6rpm_EtOH_2

ID, description, units MPD:15816   FS_6rpm_EtOH_2   latency to fall, fixed speed 6 rpm rotarod   [s]  dose: 2 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 6 rpm rotarod dose: 2 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains7 strains
Mean of the strain means100   s 83.0   s
Median of the strain means107   s 72.6   s
SD of the strain means± 26.4 ± 36.1
Coefficient of variation (CV)0.263 0.435
Min–max range of strain means62.6   –   130   s 44.1   –   138   s
Mean sample size per strain3.4   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1438.5244 1438.5244 0.7067 0.4061
strain 6 43579.0403 7263.1734 3.5684 0.0071
sex:strain 6 2893.1556 482.1926 0.2369 0.9615
Residuals 36 73275.1725 2035.4215


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 75.8 71.4   4 35.7 0.942 18.1, 180.0 -0.93
129S1/SvImJ m 44.1 16.8   4 8.4 0.381 30.6, 67.6 -1.08
B6D2F1/J f 103.0 58.7   4 29.4 0.568 47.8, 180.0 0.1
B6D2F1/J m 95.2 57.1   4 28.5 0.599 60.4, 180.0 0.34
BALB/cByJ f 126.0 40.6   4 20.3 0.323 81.6, 180.0 0.97
BALB/cByJ m 121.0 60.9   4 30.5 0.503 42.2, 180.0 1.05
BTBR T+ Itpr3tf/J f 111.0 59.9   3 34.6 0.54 71.6, 180.0 0.4
C3H/HeJ f 130.0 70.6   2   49.9 0.542 80.2, 180.0 1.12
C3H/HeJ m 138.0 49.9   4 25.0 0.363 68.7, 180.0 1.52
C57BL/6J f 62.6 9.18   4 4.59 0.147 53.7, 72.3 -1.43
C57BL/6J m 55.1 10.2   4 5.12 0.186 46.3, 69.9 -0.77
DBA/2J f 122.0 81.4   2   57.5 0.665 64.9, 180.0 0.82
DBA/2J m 72.6 14.7   2   10.4 0.203 62.2, 83.0 -0.29
FVB/NJ f 73.1 15.4   4 7.72 0.211 54.0, 91.8 -1.03
FVB/NJ m 54.8 11.0   4 5.5 0.201 42.0, 66.9 -0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 75.775 22.5578 121.5244 30.0256
129S1/SvImJ m 44.1 22.5578 89.8494 0.0
B6D2F1/J f 103.375 22.5578 149.1244 57.6256
B6D2F1/J m 95.2 22.5578 140.9494 49.4506
BALB/cByJ f 125.65 22.5578 171.3994 79.9006
BALB/cByJ m 121.05 22.5578 166.7994 75.3006
C3H/HeJ f 130.1 31.9016 194.7994 65.4006
C3H/HeJ m 137.675 22.5578 183.4244 91.9256
C57BL/6J f 62.6 22.5578 108.3494 16.8506
C57BL/6J m 55.125 22.5578 100.8744 9.3756
DBA/2J f 122.45 31.9016 187.1494 57.7506
DBA/2J m 72.6 31.9016 137.2994 7.9006
FVB/NJ f 73.15 22.5578 118.8994 27.4006
FVB/NJ m 54.825 22.5578 100.5744 9.0756


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 59.9375 15.9508 92.2872 27.5878
B6D2F1/J both 99.2875 15.9508 131.6372 66.9378
BALB/cByJ both 123.35 15.9508 155.6997 91.0003
C3H/HeJ both 133.8875 19.5356 173.5076 94.2674
C57BL/6J both 58.8625 15.9508 91.2122 26.5128
DBA/2J both 97.525 22.5578 143.2744 51.7756
FVB/NJ both 63.9875 15.9508 96.3372 31.6378




  GWAS USING LINEAR MIXED MODELS