Project measure / variable:   Crabbe3   FS_6rpm_EtOH_1

ID, description, units MPD:15815   FS_6rpm_EtOH_1   latency to fall, fixed speed 6 rpm rotarod   [s]  dose: 1 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 6 rpm rotarod dose: 1 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means123   s 118   s
Median of the strain means121   s 113   s
SD of the strain means± 34.9 ± 40.7
Coefficient of variation (CV)0.284 0.344
Min–max range of strain means60.5   –   180   s 48.0   –   177   s
Mean sample size per strain3.3   mice 3.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1301.4657 1301.4657 0.3518 0.5573
strain 5 14697.5146 2939.5029 0.7946 0.5616
sex:strain 5 7039.8579 1407.9716 0.3806 0.8583
Residuals 32 118376.1733 3699.2554


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 101.0 51.6   4 25.8 0.51 50.6, 155.0 -0.62
129S1/SvImJ m 91.8 0.0   1   0.0 0.0 91.8, 91.8 -0.65
A/J f 60.5 0.0   1   0.0 0.0 60.5, 60.5 -1.78
A/J m 48.0 0.0   1   0.0 0.0 48.0, 48.0 -1.73
B6D2F1/J f 135.0 71.9   3 41.5 0.534 51.7, 180.0 0.36
B6D2F1/J m 106.0 50.5   4 25.2 0.475 65.9, 180.0 -0.3
BALB/cByJ f 119.0 56.1   4 28.1 0.47 57.2, 180.0 -0.1
BALB/cByJ m 177.0 6.0   4 3.0 0.0339 168.0, 180.0 1.44
BTBR T+ Itpr3tf/J f 162.0 30.6   3 17.7 0.188 127.0, 180.0 1.13
BTBR T+ Itpr3tf/J m 171.0 12.7   2   9.0 0.0744 162.0, 180.0 1.3
C3H/HeJ f 121.0 76.3   4 38.1 0.629 19.8, 180.0 -0.05
C3H/HeJ m 137.0 71.0   4 35.5 0.517 32.0, 180.0 0.46
C57BL/6J f 103.0 89.8   4 44.9 0.874 12.7, 180.0 -0.56
C57BL/6J m 113.0 51.7   4 25.9 0.458 64.9, 180.0 -0.13
DBA/2J f 180.0 0.0   1   0.0 0.0 180.0, 180.0 1.65
DBA/2J m 91.2 77.4   3 44.7 0.849 38.2, 180.0 -0.66
FVB/NJ f 122.0 65.5   4 32.8 0.538 35.9, 180.0 -0.02
FVB/NJ m 129.0 60.9   4 30.5 0.473 60.1, 180.0 0.26


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J f 134.5667 35.1153 206.0942 63.0391
B6D2F1/J m 106.25 30.4108 168.1947 44.3053
BALB/cByJ f 119.375 30.4108 181.3197 57.4303
BALB/cByJ m 177.0 30.4108 238.9447 115.0553
BTBR T+ Itpr3tf/J f 162.3333 35.1153 233.8609 90.8058
BTBR T+ Itpr3tf/J m 171.0 43.0073 258.603 83.397
C3H/HeJ f 121.2 30.4108 183.1447 59.2553
C3H/HeJ m 137.25 30.4108 199.1947 75.3053
C57BL/6J f 102.75 30.4108 164.6947 40.8053
C57BL/6J m 112.875 30.4108 174.8197 50.9303
FVB/NJ f 121.725 30.4108 183.6697 59.7803
FVB/NJ m 128.675 30.4108 190.6197 66.7303


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
B6D2F1/J both 120.4083 23.2266 167.7194 73.0973
BALB/cByJ both 148.1875 21.5036 191.989 104.386
BTBR T+ Itpr3tf/J both 166.6667 27.7611 223.2142 110.1192
C3H/HeJ both 129.225 21.5036 173.0265 85.4235
C57BL/6J both 107.8125 21.5036 151.614 64.011
FVB/NJ both 125.2 21.5036 169.0015 81.3985




  GWAS USING LINEAR MIXED MODELS