Project measure / variable:   Crabbe3   FS_3rpm_EtOH_3

ID, description, units MPD:15812   FS_3rpm_EtOH_3   latency to fall, fixed speed 3 rpm rotarod   [s]  dose: 3 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 3 rpm rotarod dose: 3 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means90.7   s 73.7   s
Median of the strain means84.4   s 56.1   s
SD of the strain means± 21.8 ± 31.7
Coefficient of variation (CV)0.241 0.430
Min–max range of strain means61.9   –   138   s 36.0   –   112   s
Mean sample size per strain3.9   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3345.0368 3345.0368 1.3733 0.247
strain 8 26915.5951 3364.4494 1.3813 0.2288
sex:strain 8 17770.4418 2221.3052 0.912 0.5148
Residuals 48 116913.8525 2435.7053


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 82.3 65.3   4 32.7 0.793 42.1, 180.0 -0.39
129S1/SvImJ m 49.5 18.0   3 10.4 0.364 31.8, 67.8 -0.76
A/J f 61.9 15.4   4 7.69 0.248 44.1, 77.5 -1.32
A/J m 46.4 5.18   3 2.99 0.112 40.5, 50.3 -0.86
B6D2F1/J f 104.0 55.9   4 28.0 0.537 61.0, 180.0 0.61
B6D2F1/J m 56.1 11.0   4 5.52 0.197 40.4, 64.9 -0.56
BALB/cByJ f 72.0 13.5   4 6.75 0.188 56.8, 84.0 -0.86
BALB/cByJ m 112.0 78.3   4 39.2 0.698 39.0, 180.0 1.21
BTBR T+ Itpr3tf/J f 84.4 2.2   3 1.27 0.0261 82.3, 86.7 -0.29
BTBR T+ Itpr3tf/J m 49.8 15.2   2   10.8 0.306 39.0, 60.5 -0.75
C3H/HeJ f 138.0 68.0   4 34.0 0.493 37.6, 180.0 2.16
C3H/HeJ m 96.9 56.0   4 28.0 0.578 60.2, 180.0 0.73
C57BL/6J f 98.9 54.6   4 27.3 0.552 64.3, 180.0 0.37
C57BL/6J m 108.0 48.8   4 24.4 0.452 72.7, 180.0 1.08
DBA/2J f 91.1 59.8   4 29.9 0.657 54.2, 180.0 0.02
DBA/2J m 36.0 18.5   4 9.27 0.514 11.8, 56.8 -1.19
FVB/NJ f 83.9 83.3   3 48.1 0.992 31.7, 180.0 -0.31
FVB/NJ m 109.0 54.0   4 27.0 0.495 63.1, 180.0 1.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 82.35 24.6764 131.9653 32.7347
129S1/SvImJ m 49.5 28.4939 106.7908 0.0
A/J f 61.925 24.6764 111.5403 12.3097
A/J m 46.3667 28.4939 103.6575 0.0
B6D2F1/J f 104.25 24.6764 153.8653 54.6347
B6D2F1/J m 56.1 24.6764 105.7153 6.4847
BALB/cByJ f 71.975 24.6764 121.5903 22.3597
BALB/cByJ m 112.275 24.6764 161.8903 62.6597
BTBR T+ Itpr3tf/J f 84.4333 28.4939 141.7241 27.1425
BTBR T+ Itpr3tf/J m 49.75 34.8977 119.9166 0.0
C3H/HeJ f 137.9 24.6764 187.5153 88.2847
C3H/HeJ m 96.85 24.6764 146.4653 47.2347
C57BL/6J f 98.875 24.6764 148.4903 49.2597
C57BL/6J m 107.95 24.6764 157.5653 58.3347
DBA/2J f 91.075 24.6764 140.6903 41.4597
DBA/2J m 36.05 24.6764 85.6653 0.0
FVB/NJ f 83.9333 28.4939 141.2241 26.6425
FVB/NJ m 109.1 24.6764 158.7153 59.4847


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 65.925 18.8469 103.8193 28.0307
A/J both 54.1458 18.8469 92.0401 16.2515
B6D2F1/J both 80.175 17.4489 115.2583 45.0917
BALB/cByJ both 92.125 17.4489 127.2083 57.0417
BTBR T+ Itpr3tf/J both 67.0917 22.5264 112.384 21.7993
C3H/HeJ both 117.375 17.4489 152.4583 82.2917
C57BL/6J both 103.4125 17.4489 138.4958 68.3292
DBA/2J both 63.5625 17.4489 98.6458 28.4792
FVB/NJ both 96.5167 18.8469 134.411 58.6224




  GWAS USING LINEAR MIXED MODELS