Project measure / variable:   Crabbe3   FS_3rpm_EtOH_2

ID, description, units MPD:15811   FS_3rpm_EtOH_2   latency to fall, fixed speed 3 rpm rotarod   [s]  dose: 2 g/kg i.p.  
ethanol study
Data set, strains Crabbe3   inbred   9 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - latency to fall, fixed speed 3 rpm rotarod dose: 2 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains8 strains
Mean of the strain means93.6   s 86.5   s
Median of the strain means93.2   s 80.3   s
SD of the strain means± 33.5 ± 20.0
Coefficient of variation (CV)0.358 0.232
Min–max range of strain means42.0   –   158   s 62.9   –   117   s
Mean sample size per strain4.0   mice 4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 67.1909 67.1909 0.0377 0.8469
strain 7 15982.4491 2283.207 1.2809 0.2808
sex:strain 7 8576.8661 1225.2666 0.6874 0.682
Residuals 46 81994.1425 1782.4814


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 67.2 10.6   4 5.32 0.158 57.4, 81.7 -0.79
129S1/SvImJ m 117.0 70.9   4 35.4 0.608 45.4, 180.0 1.52
A/J f 42.0 12.6   2   8.9 0.3 33.1, 50.9 -1.54
A/J m 73.9 52.8   4 26.4 0.715 35.5, 152.0 -0.63
B6D2F1/J f 81.3 31.8   4 15.9 0.391 38.2, 111.0 -0.37
B6D2F1/J m 67.1 15.6   4 7.78 0.232 44.6, 78.7 -0.97
BALB/cByJ f 122.0 42.3   4 21.2 0.346 79.8, 180.0 0.85
BALB/cByJ m 103.0 29.8   4 14.9 0.288 60.8, 128.0 0.83
BTBR T+ Itpr3tf/J f 158.0 43.6   4 21.8 0.276 92.8, 180.0 1.92
C3H/HeJ f 93.2 61.7   4 30.8 0.662 37.2, 180.0 -0.01
C3H/HeJ m 83.6 19.7   4 9.84 0.235 55.5, 99.2 -0.14
C57BL/6J f 107.0 54.9   4 27.4 0.511 56.3, 180.0 0.4
C57BL/6J m 107.0 49.9   4 24.9 0.465 71.4, 180.0 1.03
DBA/2J f 75.6 23.2   4 11.6 0.307 49.9, 98.4 -0.54
DBA/2J m 62.9 25.8   4 12.9 0.41 40.9, 91.0 -1.18
FVB/NJ f 96.5 60.9   4 30.4 0.631 41.5, 180.0 0.09
FVB/NJ m 77.1 28.5   4 14.2 0.37 34.9, 95.6 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 67.225 21.1097 109.7167 24.7333
129S1/SvImJ m 116.55 21.1097 159.0417 74.0583
A/J f 42.0 29.8537 102.0923 0.0
A/J m 73.875 21.1097 116.3667 31.3833
B6D2F1/J f 81.3 21.1097 123.7917 38.8083
B6D2F1/J m 67.125 21.1097 109.6167 24.6333
BALB/cByJ f 122.2 21.1097 164.6917 79.7083
BALB/cByJ m 103.45 21.1097 145.9417 60.9583
C3H/HeJ f 93.2 21.1097 135.6917 50.7083
C3H/HeJ m 83.625 21.1097 126.1167 41.1333
C57BL/6J f 107.35 21.1097 149.8417 64.8583
C57BL/6J m 107.325 21.1097 149.8167 64.8333
DBA/2J f 75.6 21.1097 118.0917 33.1083
DBA/2J m 62.925 21.1097 105.4167 20.4333
FVB/NJ f 96.475 21.1097 138.9667 53.9833
FVB/NJ m 77.1 21.1097 119.5917 34.6083


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 91.8875 14.9268 121.9336 61.8414
A/J both 57.9375 18.2816 94.7364 21.1386
B6D2F1/J both 74.2125 14.9268 104.2586 44.1664
BALB/cByJ both 112.825 14.9268 142.8711 82.7789
C3H/HeJ both 88.4125 14.9268 118.4586 58.3664
C57BL/6J both 107.3375 14.9268 137.3836 77.2914
DBA/2J both 69.2625 14.9268 99.3086 39.2164
FVB/NJ both 86.7875 14.9268 116.8336 56.7414




  GWAS USING LINEAR MIXED MODELS