Phenotype measure:   Crabbe1   bal19_doseB

ID, description, units MPD:15415   bal19_doseB   missteps crossing 19.0 mm wide balance beam   [n]  dose 1.2 g/kg i.p.   measure
ethanol study
Data set, strains Crabbe1   inbred   8 strains     sex: both     age: 8-16wks
Procedure balance beam
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe1 - missteps crossing 19.0 mm wide balance beam dose 1.2 g/kg i.p.



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.88   n 2.15   n
Median of the strain means1.06   n 2.23   n
SD of the strain means± 2.48 ± 1.21
Coefficient of variation (CV)1.32 0.565
Min–max range of strain means0   –   7.68   n 0.168   –   3.92   n
Mean sample size per strain4.0   mice 4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 9.563 9.563 3.6857 0.0604
strain 7 108.0481 15.4354 5.949 < 0.0001
sex:strain 7 37.8951 5.4136 2.0864 0.0615
Residuals 52 134.9211 2.5946


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.68 5.68   2   4.01 0.739 3.67, 11.7 2.34
129S1/SvImJ m 3.42 1.71   4 0.854 0.499 1.67, 5.67 1.05
A/J f 2.5 0.577   3 0.333 0.231 2.17, 3.17 0.25
A/J m 3.92 2.22   4 1.11 0.566 1.17, 6.17 1.46
BALB/cByJ f 0.268 0.367   5 0.164 1.37 -0.65
BALB/cByJ m 1.25 1.17   4 0.584 0.932 -0.74
BTBR T+ Itpr3tf/J f 1.83 0.577   4 0.289 0.315 1.33, 2.33 -0.02
BTBR T+ Itpr3tf/J m 2.58 1.71   4 0.854 0.662 0.33, 4.33 0.36
C3H/HeJ f 0.665 0.87   4 0.435 1.31 -0.49
C3H/HeJ m 2.06 2.24   5 1.0 1.09 -0.07
C57BL/6J f 1.33 2.25   4 1.12 1.68 -0.22
C57BL/6J m 1.39 1.29   6 0.527 0.927 -0.62
DBA/2J f 0.0 0.0   5 0.0 0.0 -0.76
DBA/2J m 0.168 0.335   4 0.168 2.0 -1.63
FVB/NJ f 0.8 0.671   5 0.3 0.839 -0.44
FVB/NJ m 2.4 2.01   5 0.9 0.839 0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.685 1.139 9.9706 5.3994
129S1/SvImJ m 3.42 0.8054 5.0361 1.8039
A/J f 2.5033 0.93 4.3695 0.6372
A/J m 3.92 0.8054 5.5361 2.3039
BALB/cByJ f 0.268 0.7204 1.7135 -1.1775
BALB/cByJ m 1.2525 0.8054 2.8686 -0.3636
BTBR T+ Itpr3tf/J f 1.83 0.8054 3.4461 0.2139
BTBR T+ Itpr3tf/J m 2.58 0.8054 4.1961 0.9639
C3H/HeJ f 0.665 0.8054 2.2811 -0.9511
C3H/HeJ m 2.064 0.7204 3.5095 0.6185
C57BL/6J f 1.335 0.8054 2.9511 -0.2811
C57BL/6J m 1.3917 0.6576 2.7112 0.0721
DBA/2J f 0.0 0.7204 1.4455 -1.4455
DBA/2J m 0.1675 0.8054 1.7836 -1.4486
FVB/NJ f 0.8 0.7204 2.2455 -0.6455
FVB/NJ m 2.4 0.7204 3.8455 0.9545


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5.5525 0.6975 6.9521 4.1529
A/J both 3.2117 0.6151 4.446 1.9773
BALB/cByJ both 0.7603 0.5403 1.8444 -0.3239
BTBR T+ Itpr3tf/J both 2.205 0.5695 3.3478 1.0622
C3H/HeJ both 1.3645 0.5403 2.4486 0.2804
C57BL/6J both 1.3633 0.5199 2.4065 0.3201
DBA/2J both 0.0837 0.5403 1.1679 -1.0004
FVB/NJ both 1.6 0.5094 2.6221 0.5779




GWAS analysis not available: At least 12 strains are required